Afuco™ Anti-Human PTH ADCC Recombinant Antibody (ABX-PTH), ADCC Enhanced
CAT#: AFC-690CL
Anti-PTH ADCC Enhanced Antibody (ABX-PTH) is an ADCC enhanced antibody produced by our Afuco™ platform. The fully human monoclonal antibody that targets and neutralizes the action of parathyroid hormone (PTH). ABX-PTH is being developed for the treatment of secondary hyperparathyroidism (SHPT) which is frequently observed in patients with chronic kidney disease. Preclinical studies demonstrate ABX-PTH to be highly potent in in vivo models of SHPT.
Gene Expression
Normal Tissue
Figure 1 Parathyroid gland
Glandular cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/48540/165696_A_2_8.jpg
RNA Expression
Figure 2 RNA cell line categoryi : Not detected
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000152266-PTH/subcellular
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Specifications
- Host Species
- Human
- Derivation
- Human
- Type
- ADCC enhanced antibody
- Species Reactivity
- Human
- Related Disease
- Secondary Hyperparathyroidism
Product Property
- Purity
- >98% by SDS-PAGE and HPLC analysis
- Storage
- Store the antibody (in aliquots) at -20°C. Avoid repeated freezing and thawing of samples.
Target
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Related Diseases
Rheumatoid Arthritis
Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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See other products for "PTH"
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-718CL | Human Anti-PTH Recombinant Antibody (TAB-718CL) | ELISA | Human IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-2923 | Hi-Affi™ Recombinant Rabbit Anti-PTH Monoclonal Antibody (DS2923AB) | IHC | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0319-CN-S(P) | Human Anti-PTH Recombinant Antibody; scFv Fragment (HPAB-0319-CN-S(P)) | ELISA, IF, Neut | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0319-CN-F(E) | Human Anti-PTH Recombinant Antibody; Fab Fragment (HPAB-0319-CN-F(E)) | ELISA, IF, Neut | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| FAMAB-0322YC-VHH | Recombinant Llama Anti-PTH Single Domain Antibody (FAMAB-0322YC-VHH) | ELISA | Llama VHH |
| FAMAB-0323YC-VHH | Recombinant Llama Anti-PTH Single Domain Antibody (FAMAB-0323YC-VHH) | ELISA | Llama VHH |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-0169F | Mouse Anti-PTH Recombinant Antibody (MOB-0169F) | IHC-P, IF | Mouse IgG |
| MOB-0170F | Mouse Anti-PTH Recombinant Antibody (MOB-0170F) | IHC-P, IF | Mouse IgG |
| ZG-0200U | Mouse Anti-PTH Recombinant Antibody (clone 4D1H11) | ELISA | Mouse IgG1 |
| VS3-FY1218 | Recombinant Mouse Anti-PTH Antibody (clone 8C5H9) | ELISA, FC, IHC, ICC | Mouse IgG2b |
| VS3-FY1219 | Recombinant Mouse Anti-PTH Antibody (clone 10A7-9G5-10A10) | IHC-P | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY5838 | Anti-PTH Immunohistochemistry Kit | IHC | |
| VS-0525-XY5839 | Anti-Mouse PTH Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0625-YC271 | Recombinant Anti-PTH Eliminating Antibody, pH-Sensitive (VS-0625-YC271) | Antigen-Sweeping In Vivo. | Human IgG2 kappa |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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