Afuco™ Anti-Human PTH ADCC Recombinant Antibody (ABX-PTH), ADCC Enhanced (CAT#: AFC-690CL)
Anti-PTH ADCC Enhanced Antibody (ABX-PTH) is an ADCC enhanced antibody produced by our Afuco™ platform. The fully human monoclonal antibody that targets and neutralizes the action of parathyroid hormone (PTH). ABX-PTH is being developed for the treatment of secondary hyperparathyroidism (SHPT) which is frequently observed in patients with chronic kidney disease. Preclinical studies demonstrate ABX-PTH to be highly potent in in vivo models of SHPT.
Specific Inquiry
Normal Tissue
RNA Expression
Figure 1 Parathyroid gland
(Glandular cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/48540/165696_A_2_8.jpg
(Glandular cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/48540/165696_A_2_8.jpg
Figure 2 RNA cell line categoryi : Not detected
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000152266-PTH/subcellular
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000152266-PTH/subcellular
Specifications
- Host Species
- Human
- Derivation
- Human
- Type
- ADCC enhanced antibody
- Species Reactivity
- Human
- Related Disease
- Secondary Hyperparathyroidism
Product Property
- Purity
- >98% by SDS-PAGE and HPLC analysis
- Storage
- Store the antibody (in aliquots) at -20°C. Avoid repeated freezing and thawing of samples.
Target
- Alternative Names
- PTH; parathyroid hormone; PTH1; parathyrin; prepro-PTH; parathormone; parathyroid hormone 1; preproparathyroid hormone
- Gene ID
- 5741
- UniProt ID
- P01270
Related Resources
Rheumatoid Arthritis
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "PTH"
Human Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-718CL | Human Anti-PTH Recombinant Antibody (TAB-718CL) | ELISA | Human IgG |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-2923 | Hi-Affi™ Recombinant Rabbit Anti-PTH Monoclonal Antibody (DS2923AB) | IHC | IgG |
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0319-CN | Human Anti-PTH Recombinant Antibody (HPAB-0319-CN) | ELISA, IF, Neut | Human IgG2, κ |
| MOB-0169F | Mouse Anti-PTH Recombinant Antibody (MOB-0169F) | IHC-P, IF | Mouse IgG |
| MOB-0170F | Mouse Anti-PTH Recombinant Antibody (MOB-0170F) | IHC-P, IF | Mouse IgG |
| VS3-FY1218 | Recombinant Mouse Anti-PTH Antibody (clone 8C5H9) | ELISA, FC, IHC, ICC | Mouse IgG2b |
| VS3-FY1219 | Recombinant Mouse Anti-PTH Antibody (clone 10A7-9G5-10A10) | IHC-P | Mouse IgG1 |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0319-CN-S(P) | Human Anti-PTH Recombinant Antibody; scFv Fragment (HPAB-0319-CN-S(P)) | ELISA, IF, Neut | Human scFv |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0319-CN-F(E) | Human Anti-PTH Recombinant Antibody; Fab Fragment (HPAB-0319-CN-F(E)) | ELISA, IF, Neut | Human Fab |
Single-domain Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| FAMAB-0322YC-VHH | Recombinant Llama Anti-PTH Single Domain Antibody (PTH50) | ELISA | Llama VHH |
| FAMAB-0323YC-VHH | Recombinant Llama Anti-PTH Single Domain Antibody (PTH22) | ELISA | Llama VHH |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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