Afuco™ Anti-Human PTH ADCC Recombinant Antibody (ABX-PTH), ADCC Enhanced (CAT#: AFC-690CL)
Anti-PTH ADCC Enhanced Antibody (ABX-PTH) is an ADCC enhanced antibody produced by our Afuco™ platform. The fully human monoclonal antibody that targets and neutralizes the action of parathyroid hormone (PTH). ABX-PTH is being developed for the treatment of secondary hyperparathyroidism (SHPT) which is frequently observed in patients with chronic kidney disease. Preclinical studies demonstrate ABX-PTH to be highly potent in in vivo models of SHPT.
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Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
We require custom production
Normal Tissue
RNA Expression
Figure 1 Parathyroid gland
(Glandular cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/48540/165696_A_2_8.jpg
(Glandular cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/48540/165696_A_2_8.jpg
Figure 2 RNA cell line categoryi : Not detected
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000152266-PTH/subcellular
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000152266-PTH/subcellular
Specifications
- Host Species
- Human
- Derivation
- Human
- Type
- ADCC enhanced antibody
- Species Reactivity
- Human
- Related Disease
- Secondary Hyperparathyroidism
Product Property
- Purity
- >98% by SDS-PAGE and HPLC analysis
- Storage
- Store the antibody (in aliquots) at -20°C. Avoid repeated freezing and thawing of samples.
Target
- Alternative Names
- PTH; parathyroid hormone; PTH1; parathyrin; prepro-PTH; parathormone; parathyroid hormone 1; preproparathyroid hormone
- Gene ID
- 5741
- UniProt ID
- P01270
Related Resources
Rheumatoid Arthritis
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Human Antibody Products
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Single Domain Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-718CL | Human Anti-PTH Recombinant Antibody (TAB-718CL) | ELISA | Human IgG |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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