Afuco™ Anti-Human RYK ADCC Recombinant Antibody, ADCC Enhanced
CAT#: AFC-523CL
Anti-RYK ADCC Enhanced Antibody is an ADCC enhanced antibody produced by our Afuco™ platform. The antibodies that bind RYK, in particular human RYK are useful in treatment of cancer, inflammation and other chronic diseases and nerve injury, including peripheral nerve injury and spinal cord injury.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to the Golgi apparatus.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/75430/1614_E12_2_selected.jpg
Normal Tissue
Figure 2 IHC staining of human hippocampus
Immunohistochemical staining of human hippocampus shows strong nuclear positivity in glial cells.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/45503/ihc_selected.jpg
Normal Tissue
Figure 3 Cerebral cortex
Endothelial cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Glial cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/34117/71467_B_8_5.jpg
Normal Tissue
Figure 4 Colon
Endothelial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Peripheral nerve/ganglion Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/34117/71467_A_9_3.jpg
Normal Tissue
Figure 5 Kidney
Cells in glomeruli Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous Cells in tubules Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/34117/71467_A_8_5.jpg
Normal Tissue
Figure 6 Testis
Cells in seminiferous ducts Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/34117/71467_A_5_6.jpg
Normal Tissue
Figure 7 Endometrium
Cells in endometrial stroma Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/34117/71467_B_1_3.jpg
Normal Tissue
Figure 8 Lymph node
Non-germinal center cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/34117/71467_A_8_8.jpg
RNA Expression
Figure 9 RNA cell line category: Low cell line specificity
Cell lines ordered by descending RNA expression order
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000163785-RYK
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Specifications
- Host Species
- Human
- Derivation
- Human
- Type
- ADCC enhanced antibody
- Species Reactivity
- Human
- Related Disease
- Cancer
Product Property
- Purity
- >95% as determined by analysis by RP-HPLC
- Storage
- Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- RYK; receptor-like tyrosine kinase; JTK5; RYK1; JTK5A; D3S3195; tyrosine-protein kinase RYK; hydroxyaryl-protein kinase; JTK5A protein tyrosine kinase
- Gene ID
- 6259
- UniProt ID
- A0A087WUK1
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Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "RYK"
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-375CT | Anti-Human RYK Recombinant Antibody (RWD1) | WB, IHC, ELISA | Human antibody |
| TAB-375CT-S(P) | Anti-Human RYK Recombinant Antibody scFv Fragment (RWD1) | WB, ELISA, BL. IHC, IP, FC | Human antibody |
| TAB-375CT-F(E) | Anti-Human RYK Recombinant Antibody Fab Fragment (RWD1) | WB, ELISA, BL. IHC, IP, FC | Human antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2415CT | Recombinant Mouse anti-Human RYK Monoclonal antibody (FQS4388) | WB | |
| HPAB-M0628-YC | Mouse Anti-RYK Recombinant Antibody (HPAB-M0628-YC) | Inhib | Mouse IgG |
| HPAB-M0629-YC | Mouse Anti-RYK Recombinant Antibody (HPAB-M0629-YC) | Inhib | Mouse IgG |
| VS3-CJ887 | Mouse Anti-RYK Recombinant Antibody (VS3-CJ887) | WB, FC | Mouse IgG1, κ |
| VS3-FY2867 | Mouse Anti-RYK Recombinant Antibody (VS3-FY2867) | WB, FC | Mouse IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-3148 | Hi-Affi™ Recombinant Rabbit Anti-RYK Monoclonal Antibody (DS3148AB) | WB, IHC, ICC | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-M0628-YC-S(P) | Mouse Anti-RYK Recombinant Antibody; scFv Fragment (HPAB-M0628-YC-S(P)) | Inhib | Mouse scFv |
| HPAB-M0629-YC-S(P) | Mouse Anti-RYK Recombinant Antibody; scFv Fragment (HPAB-M0629-YC-S(P)) | Inhib | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-M0628-YC-F(E) | Mouse Anti-RYK Recombinant Antibody; Fab Fragment (HPAB-M0628-YC-F(E)) | Inhib | Mouse Fab |
| HPAB-M0629-YC-F(E) | Mouse Anti-RYK Recombinant Antibody; Fab Fragment (HPAB-M0629-YC-F(E)) | Inhib | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC472 | Recombinant Anti-RYK Vesicular Antibody, EV Displayed (VS-0425-YC472) | ELISA, FC, Inhib, Cell-uptake |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY6289 | Anti-RYK Immunohistochemistry Kit | IHC |
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