Mouse Anti-SELP Recombinant Antibody (clone 5C7.29); scFv Fragment (CAT#: HPAB-0257-YC-S(P))
The selectin family of receptors are so named because of their lectin-like domain and the selective nature of their adhesive functions. There are three known selecting, L-selectin (also known as LECAM-1, Mel-14 or LAM-1 or CD62L), E-selectin (also called ELAM-1 or CD62E) and P-selectin (also known as CD62, CD62P, GMP140 or PADGEM). The monoclonal antibody that binds to both E-selectin and to P-selectin, and inhibit the binding of these proteins to counterreceptors.
Specific Inquiry
Normal Tissue
RNA Expression
Figure 1 Colon
(Endothelial cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2145/5903_A_9_3.jpg
(Endothelial cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2145/5903_A_9_3.jpg
Figure 2 RNA cell line category: Group enriched (EFO-21, HEL)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000174175-SELP
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000174175-SELP
Figure 2 RNA cell line category: Group enriched (EFO-21, HEL)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000174175-SELP
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000174175-SELP
Specifications
- Immunogen
- L1-2E-selectin transfectants and L1-2P-selectin transfectants or lysed L1-2E-selectin cells and L1-2P-selectin cells
- Host Species
- Mouse
- Type
- Mouse scFv
- Specificity
- Human SELP
- Species Reactivity
- Human
- Clone
- 5C7.29
- Applications
- FC, Block
- Related Disease
- Inflammatory
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Flow Cytometry (FC) related Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-246 | Anti-Human selectin P Recombinant Antibody (Inclacumab) | ELISA, FC, IP, FuncS, IF, Neut, ICC | IgG4 - kappa |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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