Recombinant Anti-SELP Biparatopic Antibody, Tandem scFv (CAT#: VS-0525-YC226)

• Host Animal 1
• Human

• Host Animal 2
• Human

• Specificity
• Human SELP

• Species Reactivity
• Human

• Type
• Tandem scFv

• Valency
• 1 + 1

• Epitope 1
• A distant epitope to the PSGL-1 binding site on P-selectin.

• Epitope 2
• An epitope on the PSGL-1 binding region on P-selectin

• Purity
• >90%

• Purification
• Affinity purified

• Applications
• ELISA, FC, IP, IF

• Concentration
• Lot specific

• Buffer
• PBS, pH 7.4

• Preservative
• No preservatives

• Storage
• Store at 4°C for short term. Aliquot and store at -20°C for long term. Avoid freeze-thaw cycles.

• Long Name
• Selectin P

• Introduction
• This gene encodes a 140 kDa protein that is stored in the alpha-granules of platelets and Weibel-Palade bodies of endothelial cells. This protein redistributes to the plasma membrane during platelet activation and degranulation and mediates the interaction of activated endothelial cells or platelets with leukocytes. The membrane protein is a calcium-dependent receptor that binds to sialylated forms of Lewis blood group carbohydrate antigens on neutrophils and monocytes. Alternative splice variants may occur but are not well documented.

• Alternative Names
• Selectin P; CD62

• Gene ID
• 6403

• UniProt ID
• P16109

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