Anti-Human SEMA4A Recombinant Antibody Fab Fragment (126-28-1) (CAT#: TAB-424CT-F(E))
Recombinant monoclonal antibody specifically binds to SEMA4A. It can inhibit T cell proliferation and Th2 differentiation induced by IL-4, anti-CD3, anti-CD28 and recombinant sema4A.
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Normal Tissue
RNA Expression
Figure 1 IHC staining of human tonsil
(Immunohistochemical staining of human tonsil shows strong membranous positivity in a subset of non-germinal center cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/69136/152135_A_4_8_selected.jpg
(Immunohistochemical staining of human tonsil shows strong membranous positivity in a subset of non-germinal center cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/69136/152135_A_4_8_selected.jpg
Figure 2 Cerebral cortex
(Neuropil Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/69136/152135_B_8_5.jpg
(Neuropil Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/69136/152135_B_8_5.jpg
Figure 3 Kidney
(Cells in tubules Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/69136/152135_A_8_5.jpg
(Cells in tubules Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/69136/152135_A_8_5.jpg
Figure 4 Testis
(Leydig cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/69136/152135_A_4_6.jpg
(Leydig cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/69136/152135_A_4_6.jpg
Figure 5 Lymph node
(Non-germinal center cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/69136/152135_A_8_8.jpg
(Non-germinal center cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/69136/152135_A_8_8.jpg
Figure 6 Tonsil
(Germinal center cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/69136/152135_A_4_8.jpg
(Germinal center cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/69136/152135_A_4_8.jpg
Figure 7 RNA cell line category: Cell line enhanced (Karpas-707, U-698)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000196189-SEMA4A
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000196189-SEMA4A
Specifications
- Host Species
- Mouse
- Specificity
- Human
- Species Reactivity
- Human
- Clone
- 126-28-1
- Applications
- Used for immunoassay techniques such as: Enzyme-linked Immunosorbent Assay; Flow Cytometry; Immunohistochemistry; Blocking
- Related Disease
- Human autoimmune disease, allergic disease, inflammatory disease, graft versus host disease and graft rejection.
Target
- Alternative Names
- SEMA4A; sema domain; immunoglobulin domain (Ig); transmembrane domain (TM) and short cytoplasmic domain; (semaphorin) 4A; RP35; SEMB; SEMAB; CORD10; semaphorin-4A; sema B; semaphorin-B; anti-SEMA4A
- Gene ID
- 64218
- UniProt ID
- Q9H3S1
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Humanized Antibody Products
Mouse Antibody Products
Neutralizing Antibody Products
Antibody Magnetic Beads
Extracellular Vesicle (EV) Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-422CT | Anti-Human SEMA4A Recombinant Antibody (HuLB51) | WB, ELISA, FC | Humanized antibody |
| TAB-422CT-S(P) | Anti-Human SEMA4A Recombinant Antibody scFv Fragment (HuLB51) | WB, ELISA, FC | Humanized antibody |
| TAB-423CT-S(P) | Anti-Human SEMA4A Recombinant Antibody scFv Fragment (HuLB70) | WB, ELISA, FC | Humanized antibody |
| TAB-422CT-F(E) | Anti-Human SEMA4A Recombinant Antibody Fab Fragment (HuLB51) | WB, ELISA, FC | Humanized antibody |
| TAB-423CT-F(E) | Anti-Human SEMA4A Recombinant Antibody Fab Fragment (HuLB70) | WB, ELISA, FC | Humanized antibody |
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