The the TIM-3-specific antibody anti-TIM-3 antibody demonstrate potent and durable anti-tumor activity in syngeneic tumor models and therefore can be used for immunotherapy.
Figure 1 Anti-Human TIM3 Recombinant Antibody Fab fragment (TAB-0366CL-F(E)) in SDS-PAGE
SDS-PAGE analysis of TAB-0366CL-F(E) in non-reduced (lane 1) and reduced (lane 2) conditions. Gel stained for 30 minutes with Coomassie Blue. As a result of different β-mercaptoethanol-reduced proteins (Heavy chain and Light chain) migrate as about 26 kDa and 25 kDa, respectively.
Figure 2 Anti-Human TIM3 Recombinant Antibody Fab fragment (TAB-0366CL-F(E)) in SEC-HPLC
The purity of TAB-0366CL-F(E) was greater than 95% as determined by SEC-HPLC.
Figure 3 Anti-Human TIM3 Recombinant Antibody Fab fragment (TAB-0366CL-F(E)) in ELISA
ELISA analysis of TAB-0366CL-F(E) was performed by coating with Recombinant Human TIM3, His tag. Then blocked with BSA, and incubated with Anti-Human TIM3 Antibody (TAB-0366CL-F(E)). The HRP-conjugated goat anti-human Fab as a secondary antibody. Detection was performed using TMB substrate and stopped with sulfuric acid. The absorbances were read on a spectrophotometer at 450 nm.
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
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CAT | Product Name | Application | Type |
---|---|---|---|
MOB-976 | Recombinant Anti-Tim-3 Antibody | WB, Neut, FuncS | IgG |
MHH-976 | Recombinant Human Anti-Tim-3 Antibody | ELISA, WB, FuncS | IgG |
VS-0723-WK188 | Rabbit Anti-TIM3 Recombinant Antibody (VS-0723-WK188) | ELISA, FC | Rabbit IgG |
VS-0723-WK280 | Rabbit Anti-TIM3 Recombinant Antibody (VS-0723-WK280) | ELISA, FC | Rabbit IgG |
VS-0723-WK289 | Rabbit Anti-TIM3 Recombinant Antibody (VS-0723-WK289) | ELISA, FC | Rabbit IgG |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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