Human Anti-TREM2 Recombinant Antibody (TAB-169CQ)
CAT#: TAB-169CQ
This product is a recombinant human antibody that recognizes TREM2. The antibody was purified by affinity chromatography.
Tested Data
Gene Expression
WB
Figure 1 Anti-Human TREM2 Recombinant Antibody (TAB-169CQ) in WB
Lane 1: Non-Reducing Antigen (0.5ug)
Lane 2: Reducing Antigen (0.5ug)
ELISA
Figure 2 Anti-Human TREM2 Recombinant Antibody (TAB-169CQ) in ELISA
ELISA analysis of TAB-169CQ was performed by coating with Recombinant Human TREM2 Protein.
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Normal Tissue
Figure 1 IHC staining of human gallbladder
Immunohistochemical staining of human gallbladder shows strong membranous positivity in glandular cells.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/10917/26581_A_6_4_selected.jpg
Normal Tissue
Figure 2 Cerebral cortex
Glial cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Neuronal cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/10917/26581_B_8_5.jpg
Normal Tissue
Figure 3 Kidney
Cells in tubules Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/10917/26581_A_7_5.jpg
Normal Tissue
Figure 4 Testis
Cells in seminiferous ducts Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/10917/26581_A_6_6.jpg
RNA Expression
Figure 5 RNA cell line category: Group enriched (hTCEpi, THP-1)
Cell lines ordered by descending RNA expression order
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000095970-TREM2
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Specifications
- Immunogen
- The extracellular domain of TREM2
- Host Species
- Human
- Type
- Human IgG
- Antibody Isotype
- IgG
- Specificity
- Human
- Species Reactivity
- Human, Mouse
- Applications
- ELISA, FC, WB, FuncS
- Related Disease
- Alzheimer's disease
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
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Great For Myeloid Cells
We used this human antibody to study TREM2 expression on myeloid cells via Flow Cytometry. It binds specifically to the extracellular domain of the receptor. The results were consistent, helping us characterize immune responses in our neuroinflammation models.
High Purity Recombinant
The quality of this recombinant antibody is evident. We verified it by SDS-PAGE (>95% purity) and used it in Western Blots. It is a reliable reagent for investigating the signaling complex involving the TYRO protein tyrosine kinase binding protein.
Q&As
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What part of the TREM2 protein does this antibody recognize?
A: This recombinant human antibody recognizes the extracellular domain of TREM2 (Triggering receptor expressed on myeloid cells 2). It is purified by affinity chromatography and is suitable for detecting this membrane protein involved in immune responses and chronic inflammation.
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What applications is this antibody recommended for?
A: We recommend this antibody for ELISA, Flow Cytometry (FC), Western Blot (WB), and Functional Assays (FuncS). It is a valuable tool for researching the role of TREM2 in conditions such as Alzheimer's disease and polycystic lipomembranous osteodysplasia.
View the frequently asked questions answered by Creative Biolabs Support.
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Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "TREM2"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-168CQ | Human Anti-TREM2 Recombinant Antibody (TAB-168CQ) | ELISA, FC, WB, FuncS | Human IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-168CQ-S(P) | Human Anti-TREM2 Recombinant Antibody; scFv Fragment (TAB-168CQ-S(P)) | ELISA, FC, WB, FuncS | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-169CQ-S(P) | Human Anti-TREM2 Recombinant Antibody; scFv Fragment (TAB-169CQ-S(P)) | ELISA, FC, WB, FuncS | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-168CQ-F(E) | Human Anti-TREM2 Recombinant Antibody; Fab Fragment (TAB-168CQ-F(E)) | ELISA, FC, WB, FuncS | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-169CQ-F(E) | Human Anti-TREM2 Recombinant Antibody; Fab Fragment (TAB-169CQ-F(E)) | ELISA, FC, WB, FuncS | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0152-CN | Human Anti-TREM2 Recombinant Antibody (clone Pil.02.002) | ELISA, FC | Human IgG1, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0153-CN | Human Anti-TREM2 Recombinant Antibody (clone Pil.02.005) | ELISA, FC | Human IgG1, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0154-CN | Mouse Anti-TREM2 Recombinant Antibody (HPAB-0154-CN) | WB, ELISA, FC, IHC, IF, IP | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0155-CN | Mouse Anti-TREM2 Recombinant Antibody (HPAB-0155-CN) | WB, ELISA, FC, IHC, IF, IP | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0156-CN | Mouse Anti-TREM2 Recombinant Antibody (HPAB-0156-CN) | WB, ELISA, FC, IHC, IF, IP | Mouse IgG2b |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0152-CN-S(P) | Human Anti-TREM2 Recombinant Antibody (clone Pil.02.002); scFv Fragment | ELISA, FC | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0153-CN-S(P) | Human Anti-TREM2 Recombinant Antibody (clone Pil.02.005); scFv Fragment | ELISA, FC | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0154-CN-S(P) | Mouse Anti-TREM2 Recombinant Antibody; scFv Fragment (HPAB-0154-CN-S(P)) | WB, ELISA, FC, IHC, IF, IP | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0155-CN-S(P) | Mouse Anti-TREM2 Recombinant Antibody; scFv Fragment (HPAB-0155-CN-S(P)) | WB, ELISA, FC, IHC, IF, IP | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0156-CN-S(P) | Mouse Anti-TREM2 Recombinant Antibody; scFv Fragment (HPAB-0156-CN-S(P)) | WB, ELISA, FC, IHC, IF, IP | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0152-CN-F(E) | Human Anti-TREM2 Recombinant Antibody (clone Pil.02.002); Fab Fragment | ELISA, FC | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0153-CN-F(E) | Human Anti-TREM2 Recombinant Antibody (clone Pil.02.005); Fab Fragment | ELISA, FC | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0154-CN-F(E) | Mouse Anti-TREM2 Recombinant Antibody; Fab Fragment (HPAB-0154-CN-F(E)) | WB, ELISA, FC, IHC, IF, IP | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0155-CN-F(E) | Mouse Anti-TREM2 Recombinant Antibody; Fab Fragment (HPAB-0155-CN-F(E)) | WB, ELISA, FC, IHC, IF, IP | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0156-CN-F(E) | Mouse Anti-TREM2 Recombinant Antibody; Fab Fragment (HPAB-0156-CN-F(E)) | WB, ELISA, FC, IHC, IF, IP | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0724-XY58 | Mouse Anti-TREM2 Agonistic Antibody (clone al002c) | Agonistic assays, DB, ICC, IP, SPR, IF | Mouse IgG1, kappa |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0424-XY262 | AbPlus™ Anti-TREM2 Magnetic Beads (VS-0424-XY262) | IP, Protein Purification |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY2348 | Anti-TREM2 Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC228 | Recombinant Anti-TREM2 Vesicular Antibody, EV Displayed (VS-0425-YC228) | ELISA, FC, Cell-uptake |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY7507 | Anti-Rat TREM2 Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY7508 | Anti-Mouse TREM2 Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY7506 | Anti-Human TREM2 Immunohistochemistry Kit | IHC |
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