Cystine knot scaffold protein anti-Human IgE (CAT#: SCK-L259)
The Cystine knot that bound IgE was isolated from the library using Phage display techonology. After affinity maturation, Cystine knot variants were identified having affinities (0.1-1 nM) for IgE as determined by biosensor technology. It's potential to be used in diagnostic, research and therapeutic applications.
Specific Inquiry
RNA Expression
Figure 1 RNA cell line category: Cell line enriched (U-266/70)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000211891-IGHE
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000211891-IGHE
Figure 1 RNA cell line category: Cell line enriched (U-266/70)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000211891-IGHE
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000211891-IGHE
Specifications
- Scaffold Name
- Cystine knot
- Origin
- Native antigenic IgE receptor-contacting loops
- Core Structure
- β-stands
- Target
- IgE
- Species Reactivity
- Human
- Expression Host
- E. coli
- Affinity Constant
- 0.1-1 nM
- Applications
- ELISA; IHC; Microscopy; FC; WB; FuncS
Target
- Alternative Names
- IgE; IGHE; immunoglobulin heavy constant epsilon; immunoglobulin E
- Gene ID
- 3497
- UniProt ID
- P01854
Downloads
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See other products for "IGHE"
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1075z | Mouse Anti-IGHE Recombinant Antibody (clone 20G9) | WB, IP | Mouse IgG2a |
| HPAB-0168-LSX | Mouse Anti-IGHE Recombinant Antibody (clone MaE10) | ELISA, FC | Mouse IgG1 |
| HPAB-0169-LSX | Mouse Anti-IGHE Recombinant Antibody (clone MAE11) | ELISA, FC, SPR | Mouse IgG2 |
| HPAB-0028-YJ | Human Anti-IGHE Recombinant Antibody (clone E26) | ELISA | Humanized IgG1, κ |
| VS3-WK1515 | Mouse Anti-IGHE Recombinant Antibody (VS3-WK1515) | WB, ELISA | Mouse IgG |
Single-domain Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NABL-092 | Recombinant Anti-human IGHE VHH Single Domain Antibody | WB, ELISA, IHC, FC, FuncS | Llama VHH |
Humanized Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-755 | Anti-IGHE Recombinant Antibody (Ligelizumab) | Neut, ELISA, IF, IP, FuncS, FC, ICC | IgG1 - kappa |
| TAB-007 | Anti-Human IGHE Recombinant Antibody (Omalizumab) | WB, ELISA, IP, FC, FuncS, Neut, IF | IgG1 - kappa |
Immunotoxin
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AGTO-L061R | anti-IGHE immunotoxin (Fab)-RTA | Cytotoxicity assay, Functional assay |
Human Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-256CQ | Human Anti-IGHE Recombinant Antibody (TAB-256CQ) | Agonist | Human IgG2, κ |
| TAB-257CQ | Human Anti-IGHE Recombinant Antibody (TAB-257CQ) | Agonist | Human IgG2, κ |
| TAB-258CQ | Human Anti-IGHE Recombinant Antibody (TAB-258CQ) | Agonist | Human IgG2, κ |
| TAB-256CQ-F(E) | Human Anti-IGHE Recombinant Antibody; Fab Fragment (TAB-256CQ-F(E)) | ELISA, FC, WB | Human Fab |
| TAB-257CQ-F(E) | Human Anti-IGHE Recombinant Antibody; Fab Fragment (TAB-257CQ-F(E)) | ELISA, FC, WB | Human Fab |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0168-LSX-S(P) | Mouse Anti-IGHE Recombinant Antibody (clone MaE10); scFv Fragment | ELISA, FC | Mouse scFv |
| HPAB-0169-LSX-S(P) | Mouse Anti-IGHE Recombinant Antibody (clone MAE11); scFv Fragment | ELISA, FC | Mouse scFv |
| HPAB-0170-LSX-S(P) | Human Anti-IGHE Recombinant Antibody (clone 235-5.2); scFv Fragment | ELISA, FC | Humanized scFv |
| HPAB-0171-LSX-S(P) | Human Anti-IGHE Recombinant Antibody; scFv Fragment (HPAB-0171-LSX-S(P)) | ELISA, RIA | Human scFv |
| HPAB-0028-YJ-S(P) | Human Anti-IGHE Recombinant Antibody (clone E26); scFv Fragment | ELISA | Humanized scFv |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0170-LSX-F(E) | Human Anti-IGHE Recombinant Antibody (clone 235-5.2); Fab Fragment | ELISA, FC | Humanized Fab |
| HPAB-0171-LSX-F(E) | Human Anti-IGHE Recombinant Antibody; Fab Fragment (HPAB-0171-LSX-F(E)) | ELISA, RIA | Human Fab |
| HPAB-0172-LSX-F(E) | Human Anti-IGHE Recombinant Antibody; Fab Fragment (HPAB-0172-LSX-F(E)) | ELISA, RIA | Human Fab |
| HPAB-0173-LSX-F(E) | Human Anti-IGHE Recombinant Antibody; Fab Fragment (HPAB-0173-LSX-F(E)) | ELISA, RIA | Human Fab |
| HPAB-0028-YJ-F(E) | Human Anti-IGHE Recombinant Antibody (clone E26); Fab Fragment | ELISA | Humanized Fab |
ADCC Enhanced Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AFC-TAB-007 | Afuco™ Anti-IGHE ADCC Recombinant Antibody (Omalizumab), ADCC Enhanced | ELISA, IP, FC, FuncS, Neut | ADCC enhanced antibody |
| AFC-TAB-255 | Afuco™ Anti-IGHE ADCC Recombinant Antibody (Quilizumab), ADCC Enhanced | IP, IF, FuncS, FC, Neut | ADCC enhanced antibody |
| AFC-TAB-755 | Afuco™ Anti-IGHE ADCC Recombinant Antibody (Ligelizumab), ADCC Enhanced | Neut, ELISA, IF, IP, FuncS, FC | ADCC enhanced antibody |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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