Afuco™ Anti-IGHE ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-007) (CAT#: AFC-TAB-007)

Add to basket Submit an inquiry form Compare

• Gene Expression
• Datasheet
• MSDS
• COA

RNA Expression

Figure 1 RNA cell line category: Cell line enriched (U-266/70)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000211891-IGHE

Figure 1 RNA cell line category: Cell line enriched (U-266/70)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000211891-IGHE

 Datasheet

Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number

Specifications

Product Property

Target

Related Resources

Product Notes

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "Omalizumab"

Anti-Human IGHE Recombinant Antibody (Omalizumab)

Recombinant monoclonal antibody to Human IgE. Omalizumab is a recombinant DNA-derived humanized IgG1k monoclonal antibody that specifically binds to free human immunoglobulin E (IgE) in the blood and interstitial fluid and to membrane-bound form of IgE (mIgE) on the surface of mIgE-expressing B lymphocytes. Unlike an ordinary anti-IgE antibody, omalizumab does not bind to IgE that is already bound by the high affinity IgE receptor (FcεRI) on the surface of mast cells, basophils, and antigen-presenting dendritic cells. IgE is commonly involved in type I hypersensitivity, which manifests the most prevalent allergic diseases. It has been estimated that as high as 20 to 40% of the populations who live a western lifestyle in economically advanced countries are affected by allergy and seek medical help. In the U.S., 8% of adults and 10% of children have asthma. While allergy occurs more frequently in individuals with higher serum IgE levels, such a correlation is only statistical and not absolute. Some allergic individuals have very low serum IgE, and some people with very high IgE have no allergic problems.

DrugMonitor™ Anti-Omalizumab Antibody (VS-1224-YC841)

Omalizumab is a monoclonal antibody targeting immunoglobulin E (IgE), and it is prescribed for asthma, chronic idiopathic urticaria, chronic rhinosinusitis with nasal polyps, and IgE-mediated food allergies. The DrugMonitor™ Anti-Omalizumab Antibody (VS-1224-YC841) is an anti-drug antibody (ADA) against Omalizumab. This drug-based antibody is raised in mice immunized with the Omalizumab. The anti-Omalizumab antibody may be used in ELISA, pharmacokinetics (PK), and pharmacodynamics (PD) analyses, or serves as a reference standard in ADA assays. It also is an excellent tool for therapeutic drug monitoring, allowing to evaluate the drug efficacy and determine the drug concentration of the Omalizumab in samples.

See other products for "IGHE"

Customer Reviews and Q&As

Popular products with customers

For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.