PE-DQB1*03:02/Human TPO (IDVWLGGLAENFLP) MHC Tetramer (CAT#: MHC-LC4548)
This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of human TPO of peptide IDVWLGGLAENFLP covering 632-645 and DQB1*03:02 molecule. The pMHC tetramer recognizes CD4 T cells, and can be used in the analysis of individual antigen-specific T cells.
Specific Inquiry
Normal Tissue
RNA Expression
Figure 1 Thyroid gland
(Glandular cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/7987/21449_B_2_5.jpg
(Glandular cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/7987/21449_B_2_5.jpg
Figure 2 RNA cell line category: Group enriched (Karpas-707, RPMI-8226)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000115705-TPO/subcellular
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000115705-TPO/subcellular
Specifications
- Allele
- DQB1*03:02
- Class
- Class II
- Antigen
- TPO
- Antigen Species
- Human
- Peptide
- IDVWLGGLAENFLP
- Range
- 632-645
- Conjugate
- PE
- Application
- FCM
Target
- Antigen Introduction
- This gene encodes a membrane-bound glycoprotein. The encoded protein acts as an enzyme and plays a central role in thyroid gland function. The protein functions in the iodination of tyrosine residues in thyroglobulin and phenoxy-ester formation between pairs of iodinated tyrosines to generate the thyroid hormones, thyroxine and triiodothyronine. Mutations in this gene are associated with several disorders of thyroid hormonogenesis, including congenital hypothyroidism, congenital goiter, and thyroid hormone organification defect IIA. Multiple transcript variants encoding distinct isoforms have been identified for this gene, but the full-length nature of some variants has not been determined. [provided by RefSeq, May 2011]
- Alternative Names
- TPO; Thyroid peroxidase; MSA; TPX; TDH2A
- Gene ID
- 7173
- UniProt ID
- P07202
Related Resources
Autoimmune Thyroid Disease
Downloads
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scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-999-S(P) | Recombinant Anti-TPO Antibody scFv Fragment | ELISA, IP, FuncS | scFv |
| MHH-999-S(P) | Recombinant Human Anti-TPO Antibody scFv Fragment | WB, FC, FuncS | scFv |
| PSBW-123 | Human Anti-TPO Recombinant Antibody (clone TR1.9); scFv Fragment | WB, ELISA | Human scFv |
| HPAB-2017-FY-S(P) | Human Anti-TPO Recombinant Antibody (clone FY-019); scFv Fragment | ELISA | Human scFv |
| FAMAB-0364JF-S(P) | Human Anti-TPO Recombinant Antibody (clone RI-34); scFv Fragment | ELISA, FuncS | Human scFv |
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABW-123 | Human Anti-TPO Recombinant Antibody (clone TR1.9) | Inhib | Human IgG |
| FAMAB-0013JF | Human Anti-TPO Recombinant Antibody (clone A12) | WB, ELISA, IHC, Inhib | Human IgG |
| FAMAB-0036JF | Human Anti-TPO Recombinant Antibody (clone TF3.5) | WB, ELISA, FC | Human IgG |
| FAMAB-0042JF | Human Anti-TPO Recombinant Antibody (clone ICA5) | WB, ELISA, FuncS | Human IgG |
| VS3-FY1477 | Recombinant Mouse Anti-TPO Antibody (clone 9G3-6F3-9B7) | IHC-P | Mouse IgG2b |
Neutralizing Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-2215CQ | Mouse Anti-TPO Recombinant Antibody (clone CBL296) | Neut, ELISA | Mouse IgG2b |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-3658 | Rabbit Anti-TPO Recombinant Antibody (clone DS3658AB) | IHC-P, IP, WB | Rabbit IgG |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| FAMAB-0013JF-F(E) | Human Anti-TPO Recombinant Antibody (clone A12); Fab Fragment | WB, ELISA, FuncS | Human Fab |
| FAMAB-0014JF-F(E) | Human Anti-TPO Recombinant Antibody (clone B8); Fab Fragment | WB, ELISA, FuncS | Human Fab |
| FAMAB-0015JF-F(E) | Human Anti-TPO Recombinant Antibody (clone T5); Fab Fragment | WB, ELISA, FuncS | Human Fab |
| FAMAB-0036JF-F(E) | Human Anti-TPO Recombinant Antibody (clone TF3.5); Fab Fragment | WB, ELISA, FuncS | Human Fab |
| FAMAB-0042JF-F(E) | Human Anti-TPO Recombinant Antibody (clone ICA5); Fab Fragment | WB, ELISA, FuncS | Human Fab |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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