PE-H-2Kd/Human JAK1 (SYFPEITHI) MHC Tetramer

CAT#: MHC-LC206

This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of JAK1-derived peptide of SYFPEITHI sequence covering 367-375 and H-2Kd molecule. The pMHC tetramer recognizes mouse CD8 T cells, and can be used in the analysis of individual antigen-specific T cells.

Gene Expression
Figure 1 IHC staining of human tonsil Figure 2 Cerebral cortex Figure 3 Colon Figure 4 Liver Figure 5 Kidney Figure 6 Testis Figure 7 Lymph node Figure 8 RNA cell line category: Cell line enhanced (ASC diff)

Specifications

  • Allele
  • H-2Kd
  • Class
  • Class I
  • MHC Species
  • Mouse
  • Antigen
  • JAK1
  • Antigen Species
  • Human
  • Peptide
  • SYFPEITHI
  • Range
  • 367-375
  • Conjugate
  • PE
  • Application
  • FCM

Target

  • Antigen Introduction
  • This gene encodes a membrane protein that is a member of a class of protein-tyrosine kinases (PTK) characterized by the presence of a second phosphotransferase-related domain immediately N-terminal to the PTK domain. The encoded kinase phosphorylates STAT proteins (signal transducers and activators of transcription) and plays a key role in interferon-alpha/beta and interferon-gamma signal transduction. Alternative splicing results in multiple transcript variants.
  • Alternative Names
  • JAK1; Janus kinase 1; JTK3; JAK1A; JAK1B
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