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    Recombinant Anti-Human ICAM1 Antibody (Fc glycosylation) (CAT#: Gly-104LC)

    This product is a mouse monoclonal antibody with glycosylation in Fc region by which the antibody has an increased half-life. Antibody Enlimomab specifically binds human ICAM-1 and can be potentially used in the treatment of acute stroke.

    Specific Inquiry
    • Size:

    • Conjugation:

    • Endotoxin:

    • Purity:

    • Gene Expression
    • Datasheet
    • MSDS
    • COA
    Subcellular Location and Protein Expression
    Figure 1 IF staining of human cell line U-2 OS
    Figure 1 IF staining of human cell line U-2 OS
    (Immunofluorescent staining of human cell line U-2 OS shows localization to plasma membrane & cytosol.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2126/29_G3_2_selected.jpg
    Figure 2 IF staining of human cell line U-251 MG
    Figure 2 IF staining of human cell line U-251 MG
    (Immunofluorescent staining of human cell line U-251 MG shows localization to plasma membrane.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2142/203_G3_1_selected.jpg
    Figure 3 IF staining of human cell line EFO-21
    Figure 3 IF staining of human cell line EFO-21
    (Immunofluorescent staining of human cell line EFO-21 shows localization to plasma membrane & cytosol.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2126/1937_A10_1_blue_red_green.jpg
    Figure 4 IF staining of human cell line GAMG
    Figure 4 IF staining of human cell line GAMG
    (Immunofluorescent staining of human cell line GAMG shows localization to plasma membrane, vesicles, nucleoplasm & centrosome.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2126/2058_A10_4_blue_red_green.jpg
    Normal Tissue
    Figure 5 Cerebral cortex
    Figure 5 Cerebral cortex
    (Endothelial cells
    Staining:Medium
    Intensity: Moderate
    Quantity:>75%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2126/7230_B_9_5.jpg
    Figure 6 Lung
    Figure 6 Lung
    (Alveolar cells
    Staining:High
    Intensity: Strong
    Quantity:>75%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2126/7230_A_3_4.jpg
    Figure 7 Colon
    Figure 7 Colon
    (Endothelial cells
    Staining:High
    Intensity: Strong
    Quantity:>75%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/4877/13410_A_8_3.jpg
    Figure 8 Kidney
    Figure 8 Kidney
    (Cells in glomeruli
    Staining:High
    Intensity: Strong
    Quantity:>75%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/4877/13410_A_8_5.jpg
    Figure 9 Lymph node
    Figure 9 Lymph node
    (Non-germinal center cells
    Staining:Medium
    Intensity: Strong
    Quantity: <25%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/4877/13410_A_9_8.jpg
    RNA Expression
    Figure 10 RNA cell line category: Cell line enhanced (HHSteC, Karpas-707, RPMI-8226)
    Figure 10 RNA cell line category: Cell line enhanced (HHSteC, Karpas-707, RPMI-8226)
    (Cell lines ordered by descending RNA expression order.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000090339-ICAM1

    Glyco-engineering

    • Glycosylation site
    • Fc region
    • Glycosylation Type
    • N-glycosylation
    • Activity
    • Increased half-life

    Specifications

    • Target
    • ICAM-1 (Intercellular Adhesion Molecule 1)
    • Host Species
    • Mouse
    • Type
    • Mouse antibody
    • Specificity
    • Human
    • Clone
    • Enlimomab
    • Applications
    • ELISA

    Target

    • Alternative Names
    • ICAM1; intercellular adhesion molecule 1; BB2; CD54; P3.58; ICAM-1; cell surface glycoprotein P3.58; major group rhinovirus receptor; intercellular adhesion molecule 1 (CD54), human rhinovirus receptor
    • Related Disease
    • Acute stroke

    Related Resources

    • Related Diseases
    • Related Signaling Pathways

    Downloads

    Download resources about recombinant antibody development and antibody engineering to boost your research.

    See other products for "ICAM1"

    Select a product category from the dropdown menu below to view related products.
    Please select product type
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    CAT Product Name Application Type
    NAB-1937-VHH Recombinant Anti-human ICAM1 VHH Single Domain Antibody FA, FC, ICC, ELISA Llama VHH
    TAB-126CT Llama Anti-ICAM1 Recombinant Antibody (TAB-126CT) ELISA, IF Llama VHH
    HPAB-0349-YC-VHH Recombinant Llama Anti-ICAM1 Single Domain Antibody (HPAB-0349-YC-VHH) ELISA Llama VHH

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    For Research Use Only. Not For Clinical Use.

    For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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