Human Anti-ICAM1 (clone 1A6) scFv-Fc Chimera
CAT#: VS-0125-FY45
Anti-ICAM-1 scFv-Fc is a recombinant fusion protein designed to target and bind to intercellular adhesion molecule 1 (ICAM-1). The single-chain variable fragment (scFv) component provides high specificity and affinity for ICAM-1, which is a cell adhesion molecule involved in various cellular processes such as immune response, inflammation, and leukocyte migration. The Fc region derived from human IgG enhances the stability and solubility of the scFv, allowing it to retain the functional properties associated with antibodies.
Gene Expression
Subcellular Location and Protein Expression
Figure 1 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to plasma membrane & cytosol.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2126/29_G3_2_selected.jpg
Subcellular Location and Protein Expression
Figure 2 IF staining of human cell line U-251 MG
Immunofluorescent staining of human cell line U-251 MG shows localization to plasma membrane.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2142/203_G3_1_selected.jpg
Subcellular Location and Protein Expression
Figure 3 IF staining of human cell line EFO-21
Immunofluorescent staining of human cell line EFO-21 shows localization to plasma membrane & cytosol.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2126/1937_A10_1_blue_red_green.jpg
Subcellular Location and Protein Expression
Figure 4 IF staining of human cell line GAMG
Immunofluorescent staining of human cell line GAMG shows localization to plasma membrane, vesicles, nucleoplasm & centrosome.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2126/2058_A10_4_blue_red_green.jpg
Normal Tissue
Figure 5 Cerebral cortex
Endothelial cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2126/7230_B_9_5.jpg
Normal Tissue
Figure 6 Lung
Alveolar cells
Staining:High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2126/7230_A_3_4.jpg
Normal Tissue
Figure 7 Colon
Endothelial cells
Staining:High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/4877/13410_A_8_3.jpg
Normal Tissue
Figure 8 Kidney
Cells in glomeruli
Staining:High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/4877/13410_A_8_5.jpg
Normal Tissue
Figure 9 Lymph node
Non-germinal center cells
Staining:Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/4877/13410_A_9_8.jpg
RNA Expression
Figure 10 RNA cell line category: Cell line enhanced (HHSteC, Karpas-707, RPMI-8226)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000090339-ICAM1
❮
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Specifications
- Host Species
- Human
- Type
- Human IgG1, scFv-Fc
- Species Reactivity
- Human
- Clone
- 1A6
- Applications
- Antibody-dependent cellular cytotoxicity
- Related Disease
- Cancer
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Stabilizer
- No Stabilizers
- Sterility
- 0.2 μM filtered
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Ice packs
Target
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Related Diseases
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Related Signaling Pathways
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Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Secondary Antibody
- CAT
- Product Name
Isotype Control
- CAT
- Product Name
See other products for "Clone 1A6"
- CAT
- Product Name
See other products for "ICAM1"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NAB-1937-VHH | Recombinant Anti-human ICAM1 VHH Single Domain Antibody | FA, FC, ICC, ELISA | Llama VHH |
| TAB-126CT | Llama Anti-ICAM1 Recombinant Antibody (TAB-126CT) | ELISA, IF | Llama VHH |
| HPAB-0349-YC-VHH | Recombinant Llama Anti-ICAM1 Single Domain Antibody (HPAB-0349-YC-VHH) | ELISA | Llama VHH |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-241 | Anti-Human ICAM-1 Recombinant Antibody Fab Fragment (TAB-241) | WB, IF, IP, Neut, FuncS, ELISA, FC | Fab' - G2a |
| TAB-H26 | Anti-Human ICAM1 Recombinant Antibody (TAB-H26) | Neut, ELISA, IF, IP, FuncS, FC, WB | IgG2a |
| TAB-124CT | Anti-Human ICAM-1 Recombinant Antibody (m1A6) | ELISA | |
| TAB-124CT-S(P) | Anti-Human ICAM-1 Recombinant Antibody scFv Fragment (m1A6) | ELISA | |
| TAB-124CT-F(E) | Anti-Human ICAM-1 Recombinant Antibody Fab Fragment (m1A6) | ELISA |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AGTO-L023R | anti-ICAM1 immunotoxin UV3 (IgG)-RTA | Cytotoxicity assay, Functional assay |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-376CL | Human Anti-ICAM1 Recombinant Antibody (TAB-376CL) | IHC, FuncS | Human IgG1 |
| TAB-121CT | Anti-Human ICAM-1 Recombinant Antibody (MD-2) | ELISA, FC | Human antibody |
| TAB-121CT-F(E) | Anti-Human ICAM-1 Recombinant Antibody Fab Fragment (MD-2) | ELISA, FC | Human antibody |
| TAB-122CT-F(E) | Anti-Human ICAM-1 Recombinant Antibody Fab Fragment (R6-5-D6) | ELISA, FC | Human antibody |
| TAB-125CT-F(E) | Anti-Human ICAM-1 Recombinant Antibody Fab Fragment (ICM 10064) | Inhibit, ELISA, WB | Human antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PFBZ-079 | Mouse Anti-ICAM1 Recombinant Antibody (clone CA7); Fab Fragment | FC | Mouse Fab |
| HPAB-662-FY-F(E) | Human Anti-ICAM1 Recombinant Antibody Fab Fragment (HPAB-662-FY-F(E)) | Inhib | Human Fab |
| HPAB-S0062-YC-F(E) | Human Anti-ICAM1 Recombinant Antibody (clone HumB); Fab Fragment | ELISA, FuncS | Humanized Fab |
| HPAB-S0063-YC-F(E) | Human Anti-ICAM1 Recombinant Antibody (clone HumC); Fab Fragment | ELISA, FuncS | Humanized Fab |
| HPAB-S0064-YC-F(E) | Human Anti-ICAM1 Recombinant Antibody (clone HumD); Fab Fragment | ELISA, FuncS | Humanized Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-123CT | Anti-Human ICAM-1 Recombinant Antibody (h1A6) | ELISA | Humanized antibody |
| TAB-123CT-S(P) | Anti-Human ICAM-1 Recombinant Antibody scFv Fragment (h1A6) | ELISA | Humanized antibody |
| TAB-123CT-F(E) | Anti-Human ICAM-1 Recombinant Antibody Fab Fragment (h1A6) | ELISA | Humanized antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| Gly-104LC | Recombinant Anti-Human ICAM1 Antibody (Fc glycosylation) | ELISA | Mouse antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-923CQ | Mouse Anti-ICAM1 Recombinant Antibody (clone CBL236) | Neut, IF, FC, WB, IHC | Mouse IgG1 |
| NEUT-925CQ | Mouse Anti-ICAM1 Recombinant Antibody (NEUT-925CQ) | FC, FuncS, IHC, Neut, WB | Mouse IgG1, κ |
| NEUT-926CQ | Mouse Anti-ICAM1 Recombinant Antibody (VMC182) | FC, IF, IHC, ICC, Neut | Mouse IgG2b |
| NEUT-927CQ | Mouse Anti-ICAM1 Recombinant Antibody (NEUT-927CQ) | FC, IF, IHC, Neut, WB, ELISA | Mouse IgG1 |
| NEUT-930CQ | Rat Anti-Icam1 Recombinant Antibody (NEUT-930CQ) | FC, FuncS, IHC-Fr, Neut, IP | Rat IgG2a, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-924CQ | Mouse Anti-ICAM1 Recombinant Antibody (clone HCD54) | FC, IF, Block | Mouse IgG1, κ |
| NEUT-928CQ | Mouse Anti-ICAM1 Recombinant Antibody (VMC183) | Block, FC, IHC, IP | Mouse IgG1 |
| NEUT-929CQ | Mouse Anti-ICAM1 Recombinant Antibody (NEUT-929CQ) | Block, WB, IP, ICC | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1723 | Rabbit Anti-ICAM1 Recombinant Antibody (clone DS1723AB), Biotin | IHC-Fr, IP, WB, ELISA | Rabbit IgG |
| MOR-1724 | Rabbit Anti-Icam1 Recombinant Antibody (clone DS1724AB) | ELISA | Rabbit IgG |
| MOR-4598 | Rabbit Anti-ICAM1 Recombinant Antibody (clone TH111DS) | WB, FC | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| EPAF-1635LC | Mouse Anti-ICAM1 Recombinant Antibody (clone c78.4A) | FC | Mouse IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0043-FY-S(P) | Human Anti-ICAM1 Recombinant Antibody scFv Fragment (HPAB-0043-FY-S(P)) | ELISA | Human scFv |
| HPAB-662-FY-S(P) | Human Anti-ICAM1 Recombinant Antibody scFv Fragment (HPAB-662-FY-S(P)) | Inhib | Human scFv |
| HPAB-1728-FY-F(E) | Human Anti-ICAM1 Recombinant Antibody (clone LAC1555); scFv Fragment | ELISA | Human scFv |
| HPAB-1729-FY-F(E) | Human Anti-ICAM1 Recombinant Antibody (clone LAC3040); scFv Fragment | ELISA | Human scFv |
| HPAB-1730-FY-F(E) | Human Anti-ICAM1 Recombinant Antibody (clone LAC3041); scFv Fragment | ELISA | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-1728-FY | Human Anti-ICAM1 Recombinant Antibody (clone LAC1555) | ELISA | Human IgG4 |
| HPAB-1729-FY | Human Anti-ICAM1 Recombinant Antibody (clone LAC3040) | ELISA | Human IgG4 |
| HPAB-1730-FY | Human Anti-ICAM1 Recombinant Antibody (clone LAC3041) | ELISA | Human IgG4 |
| ZG-0389F | Mouse Anti-ICAM1 Recombinant Antibody (ZG-0389F) | WB | Mouse IgG |
| ZG-0476J | Mouse Anti-ICAM1 Recombinant Antibody (ZG-0476J) | WB, IF | Mouse IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0424-XY141 | AbPlus™ Anti-ICAM1 Magnetic Beads (15.2) | IP, Protein Purification | |
| VS-0724-YC1353 | AbPlus™ Anti-Icam1 Magnetic Beads (VS-0724-YC1353) | IP, Protein Purification |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0225-XY121 | CytoStream™ Mouse Anti-ICAM1 Recombinant Antibody (clone HA58) | FC | Mouse IgG1, kappa |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC540 | Recombinant Anti-ICAM1 Vesicular Antibody, EV Displayed (VS-0425-YC540) | ELISA, FC, Neut, Cell-uptake |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY3367 | Anti-Mouse ICAM1 Immunohistochemistry Kit | IHC | |
| VS-0525-XY3370 | Anti-Rat ICAM1 Immunohistochemistry Kit | IHC |
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