Recombinant Anti-Human IL7R Antibody (Non-glycosylated)
CAT#: Gly-131LC
This product is a non-glycosylated chimeric (rat/mouse) monoclonal antibody. The glyco-engineered antibody has increased efficacy as well as decreased side effect, it specficfically binds to human IL-7R and can be potentially used in the treatment of Type 1 diabetes.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line REH
Immunofluorescent staining of human cell line REH shows localization to plasma membrane.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/67550/1779_G6_3_selected.jpg
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Glyco-engineering
- Activity
- Increased efficacy and/or decreased side effects
Specifications
- Target
- IL-7R (Interleukin 6 receptor)
- Host Species
- Human
- Type
- Chimeric antibody (rat/mouse)
- Specificity
- Human
- Clone
- agly-28G9
- Expression Host
- 293F
- Applications
- ELISA
Target
- Alternative Names
- IL7R; interleukin 7 receptor; ILRA; CD127; IL7RA; CDW127; IL-7R-alpha; interleukin-7 receptor subunit alpha; IL-7RA; CD127 antigen; IL-7R subunit alpha; IL-7 receptor subunit alpha; interleukin 7 receptor alpha chain; interleukin 7 receptor isoform H5-6
- Related Disease
- Type 1 diabetes
- Gene ID
- 3575
- UniProt ID
- P16871
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COA
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| TAB-698LC-F(E) | Rat Anti-IL7R Recombinant Antibody; Fab Fragment (TAB-698LC-F(E)) | ELISA, FC | Rat Fab |
| CAT | Product Name | Application | Type |
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| TAB-700LC-S(P) | Human Anti-IL7R Recombinant Antibody; scFv Fragment (TAB-700LC-S(P)) | ELISA, FC | Human scFv |
| TAB-699LC-F(E) | Human Anti-IL7R Recombinant Antibody; Fab Fragment (TAB-699LC-F(E)) | ELISA, FC | Chimeric (Rat/Human) Fab |
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| CAT | Product Name | Application | Type |
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| CAT | Product Name | Application | Type |
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| CAT | Product Name | Application | Type |
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| HPAB-0426-CN-F(E) | Rat Anti-IL7R Recombinant Antibody; Fab Fragment (HPAB-0426-CN-F(E)) | ELISA, FC, Block | Rat Fab |
| HPAB-0427-CN-F(E) | Rat Anti-IL7R Recombinant Antibody; Fab Fragment (HPAB-0427-CN-F(E)) | ELISA, FC, Block | Rat Fab |
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| HPAB-0429-CN-F(E) | Human Anti-IL7R Recombinant Antibody; Fab Fragment (HPAB-0429-CN-F(E)) | ELISA, FC, Block | Human Fab |
| CAT | Product Name | Application | Type |
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