Recombinant Anti-IL7R Vesicular Antibody, EV Displayed (VS-0425-YC100)
CAT#: VS-0425-YC100
The Recombinant Anti-IL7R Vesicular Antibody, EV Displayed (VS-0425-YC100) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to IL7R-expressed cells or tissues. The IL7R is a receptor for interleukin 7, crucial for lymphocyte development and linked to severe immunodeficiencies.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line REH
Immunofluorescent staining of human cell line REH shows localization to plasma membrane.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/67550/1779_G6_3_selected.jpg
Subcellular Location
Figure 2 IF staining of human cell line U-251 MG
Immunofluorescent staining of human cell line U-251 MG shows localization to plasma membrane & centriolar satellites.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/10215/209_B7_2_selected.jpg
Subcellular Location
Figure 3 IF staining of human cell line A-431
Immunofluorescent staining of human cell line A-431 shows localization to plasma membrane.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/10215/210_B7_2_blue_red_green.jpg
Subcellular Location
Figure 4 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to Centriolar satellite.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/10215/211_B7_2_blue_red_green.jpg
RNA Expression
Figure 5 RNA cell line category: Cell line enhanced (BJ, BJ hTERT+ SV40 Large T+, fHDF/TERT166, HBF TERT88, REH)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000168685-IL7R
❮
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Recombinant Antibody
- Application
- ELISA, FC, Inhib, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- IL7R
- Host Animal
- Human
- Antibody Isotype
- IgG
- Species Reactivity
- Human
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- z domain
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Binding Affinity
- Kd = 0.85 µg/mL
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- Interleukin 7 receptor
- Molecular Function
- Receptor
- Cellular Localization
- Plasma membrane
- Introduction
- The protein encoded by this gene is a receptor for interleukin 7 (IL7). The function of this receptor requires the interleukin 2 receptor, gamma chain (IL2RG), which is a common gamma chain shared by the receptors of various cytokines, including interleukins 2, 4, 7, 9, and 15. This protein has been shown to play a critical role in V(D)J recombination during lymphocyte development. Defects in this gene may be associated with severe combined immunodeficiency (SCID). Alternatively spliced transcript variants have been found.
- Alternative Names
- CD127, IL7RA, lnc-IL7R
- Gene ID
- 3575
- UniProt ID
- P16871
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Datasheet
MSDS
COA
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-437CL | Human Anti-IL7R Recombinant Antibody (TAB-437CL) | ELISA | Human IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-698LC | Rat Anti-IL7R Recombinant Antibody (TAB-698LC) | ELISA, FC, Inhib, ADCC, FuncS | Rat IgG |
| TAB-698LC-S(P) | Rat Anti-IL7R Recombinant Antibody; scFv Fragment (TAB-698LC-S(P)) | ELISA, FC | Rat scFv |
| TAB-698LC-F(E) | Rat Anti-IL7R Recombinant Antibody; Fab Fragment (TAB-698LC-F(E)) | ELISA, FC | Rat Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-699LC | Human Anti-IL7R Recombinant Antibody (TAB-699LC) | ELISA, FC, Inhib, ADCC | Chimeric (Rat/Human) IgG1 |
| TAB-699LC-S(P) | Human Anti-IL7R Recombinant Antibody; scFv Fragment (TAB-699LC-S(P)) | ELISA, FC | Human scFv |
| TAB-700LC-S(P) | Human Anti-IL7R Recombinant Antibody; scFv Fragment (TAB-700LC-S(P)) | ELISA, FC | Human scFv |
| TAB-699LC-F(E) | Human Anti-IL7R Recombinant Antibody; Fab Fragment (TAB-699LC-F(E)) | ELISA, FC | Chimeric (Rat/Human) Fab |
| TAB-700LC-F(E) | Human Anti-IL7R Recombinant Antibody; Fab Fragment (TAB-700LC-F(E)) | ELISA, FC | Chimeric (Rat/Human) Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| Gly-130LC | Recombinant Anti-Human IL7R Antibody (Fc glycosylation) | ELISA | Rat antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| Gly-131LC | Recombinant Anti-Human IL7R Antibody (Non-glycosylated) | ELISA | Chimeric antibody (rat/mouse) |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1511CQ | Mouse Anti-IL7R Recombinant Antibody (clone R34-34) | Neut, Flow, IP | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1512CQ | Rat Anti-Il7r Recombinant Antibody (NEUT-1512CQ) | Block, FC | Rat IgG2 |
| NEUT-1513CQ | Rat Anti-Il7r Recombinant Antibody (clone A7R34) | Block, FC | Rat IgG2a |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1816 | Rabbit Anti-IL7R Recombinant Antibody (clone DS1816AB) | WB, FC | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0315-YC-S(P) | Rat Anti-IL7R Recombinant Antibody; scFv Fragment (HPAB-0315-YC-S(P)) | FuncS | Rat scFv |
| HPAB-0426-CN-S(P) | Rat Anti-IL7R Recombinant Antibody; scFv Fragment (HPAB-0426-CN-S(P)) | ELISA, FC, Block | Rat scFv |
| HPAB-0427-CN-S(P) | Rat Anti-IL7R Recombinant Antibody; scFv Fragment (HPAB-0427-CN-S(P)) | ELISA, FC, Block | Rat scFv |
| HPAB-3175LY-S(P) | Mouse Anti-IL7R Recombinant Antibody; scFv Fragment (HPAB-3175LY-S(P)) | IHC, IP, FC, IF, ELISA, WB | Mouse scfv |
| HPAB-3176LY-S(P) | Mouse Anti-IL7R Recombinant Antibody; scFv Fragment (HPAB-3176LY-S(P)) | IHC, IP, FC, IF, ELISA, WB | Mouse scfv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0315-YC-F(E) | Rat Anti-IL7R Recombinant Antibody; Fab Fragment (HPAB-0315-YC-F(E)) | FuncS | Rat Fab |
| HPAB-0426-CN-F(E) | Rat Anti-IL7R Recombinant Antibody; Fab Fragment (HPAB-0426-CN-F(E)) | ELISA, FC, Block | Rat Fab |
| HPAB-0427-CN-F(E) | Rat Anti-IL7R Recombinant Antibody; Fab Fragment (HPAB-0427-CN-F(E)) | ELISA, FC, Block | Rat Fab |
| HPAB-0428-CN-F(E) | Rat Anti-IL7R Recombinant Antibody; Fab Fragment (HPAB-0428-CN-F(E)) | ELISA, FC, Block | Rat Fab |
| HPAB-0429-CN-F(E) | Human Anti-IL7R Recombinant Antibody; Fab Fragment (HPAB-0429-CN-F(E)) | ELISA, FC, Block | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0426-CN | Rat Anti-IL7R Recombinant Antibody (HPAB-0426-CN) | ELISA, FC, Block | Rat IgG2a |
| HPAB-0427-CN | Rat Anti-IL7R Recombinant Antibody (HPAB-0427-CN) | ELISA, FC, Block | Rat IgG2a |
| HPAB-0429-CN | Human Anti-IL7R Recombinant Antibody (HPAB-0429-CN) | ELISA, FC, Block | Human IgG1 |
| HPAB-3175LY | Mouse Anti-IL7R Recombinant Antibody (HPAB-3175LY) | IHC, IP, FC, IF, ELISA, WB | Mouse IgG1 |
| HPAB-3176LY | Mouse Anti-IL7R Recombinant Antibody (HPAB-3176LY) | FC | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-FY43 | Mouse Anti-IL7R (clone 1A11) scFv-Fc Chimera | ELISA | Mouse IgG1, scFv-Fc |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY3543 | Anti-Mouse IL7R Immunohistochemistry Kit | IHC |
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