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Anti-IL7R Recombinant Antibody Products

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Anti-IL7R Products

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For Research Use Only. Not For Clinical Use.


Creative Biolabs is dedicated to providing high-quality anti-IL7R antibodies to support biomedical research. Recognizing the critical role of precise antibodies in scientific progress, we uphold strict quality and reliability standards. Our commitment to excellence ensures researchers have access to dependable tools, empowering them to make significant advancements in their studies.

IL7R: A Key Transmembrane Protein in Immune System Regulation

Interleukin-7 receptor (IL7R) is a key transmembrane protein involved in immune system regulation. It is primarily expressed on T cells, B cell precursors, and other immune cells, playing a crucial role in lymphocyte development, survival, and homeostasis. IL7R consists of two subunits: IL7Rα (CD127) and the common gamma chain (γc), which together mediate signaling upon binding to its ligand, interleukin-7 (IL-7). This interaction activates the JAK-STAT and PI3K-AKT pathways, promoting cell proliferation, differentiation, and survival. IL7R is essential for proper immune function, and its dysregulation is associated with various diseases, including severe combined immunodeficiency (SCID), autoimmune disorders, and certain cancers such as leukemia. Due to its critical role in immune cell regulation, IL7R has become an important target for therapeutic research, with ongoing studies exploring its potential in immunotherapy and autoimmune disease treatment.

Alternative Names

ILRA; CD127; IL7RA; CDW127; IMD104; sIL-7R; lnc-IL7R; IL7Ralpha; IL-7Ralpha; IL-7R-alpha

Background

The protein encoded by this gene is a receptor for interleukin 7 (IL7). The function of this receptor requires the interleukin 2 receptor, gamma chain (IL2RG), which is a common gamma chain shared by the receptors of various cytokines, including interleukins 2, 4, 7, 9, and 15. This protein has been shown to play a critical role in V(D)J recombination during lymphocyte development. Defects in this gene may be associated with severe combined immunodeficiency (SCID). Alternatively spliced transcript variants have been found.

Anti-IL7R rAb Products

We are committed to providing high-quality anti-IL7R recombinant antibodies to enhance research in target-based drug development. Our aim is to drive scientific progress by delivering reliable and top-performing products that support researchers in their discovery efforts.

Cat. No. Product Name Target Species Host Species Applications
TAB-437CL Human Anti-IL7R Recombinant Antibody Human Human ELISA
TAB-699LC Human Anti-IL7R Recombinant Antibody Human Human ELISA; FC; Inhib; ADCC
HPAB-0426-CN Rat Anti-IL7R Recombinant Antibody Human; Cynomolgus; Baboon Rat ELISA; FC; Block
HPAB-1471-FY Mouse Anti-IL7R Recombinant Antibody (clone 6C5) Human Mouse ELISA; FC; Inhib
HPAB-0315-YC Rat Anti-IL7R Recombinant Antibody Human Rat FuncS

Creative Quality Control

Our team is committed to delivering superior antibody products, carefully developed using cutting-edge technologies and stringent quality control measures. We prioritize excellence to ensure reliability and precision in every product. By providing high-performance antibodies, we aim to support scientific progress and facilitate the development of more effective therapies targeting IL7R, ultimately contributing to advancements in biomedical research and drug discovery.

SDS-PAGE analysis of TAB-437CL. (Creative Biolabs Original)Fig.1 SDS-PAGE analysis of anti-IL7R antibody
(Cat# TAB-437CL, Creative Biolabs).

SEC-HPLC analysis of TAB-437CL. (Creative Biolabs Original)Fig.2 SEC-HPLC analysis of anti-IL7R antibody
(Cat# TAB-437CL, Creative Biolabs).

Customer Reviews

Excellent
Gi**rt
Human Anti-IL7R Recombinant Antibody (Cat#:TAB-437CL)
The Human Anti-IL7R Recombinant Antibody specifically targets Interleukin-7 Receptor and is suitable for applications like ELISA. It supports research on T-cell development, immune disorders, and related diseases. Recombinant production ensures consistent and reliable results across experiments.
7/May/2023
Excellent
Ch**les
Human Anti-IL7R Recombinant Antibody (Cat#:TAB-699LC)
The Human Anti-IL7R Recombinant Antibody is suitable for detecting IL7R in immune cells, with applications in flow cytometry and ELISA. It supports studies on T-cell development, autoimmune diseases, and blood cancers. Recombinant production ensures consistent and reproducible results for research and clinical use.
20/Sep/2024

rAb Production

With extensive experience in expression vector optimization, transfected cell line selection, and antibody purification, we provide end-to-end services, covering everything from gene synthesis to antibody production. Our expertise ensures efficient workflows and high-yield antibody generation, supporting researchers in biomedical and pharmaceutical studies. By integrating advanced screening techniques and purification strategies, we deliver consistent, high-quality solutions tailored to diverse research needs. Whether for therapeutic development or fundamental studies, our services enhance reliability and efficiency at every stage, helping scientists achieve reproducible and meaningful results.

Featured Anti-IL7R Recombinant Antibody Production PlatformsMilligram-scale anti-IL7R recombinant antibody production. (Creative Biolabs Original)
Fig.3 Milligram-scale recombinant antibody production.

Gram-scale anti-IL7R recombinant antibody production. (Creative Biolabs Original)Fig.4 Gram-scale recombinant antibody production.

rAb Modalities

Creative Biolabs specializes in delivering a wide range of recombinant antibody formats customized for different research applications, from basic science to drug discovery. Our antibodies are carefully developed to ensure exceptional quality, reliability, and performance, meeting the unique requirements of researchers. With a focus on versatile and innovative solutions, we strive to accelerate scientific advancements and biomedical breakthroughs. By continuously refining our technologies and expanding our offerings, we provide researchers with the tools they need to drive progress in therapeutic development and cutting-edge research.

Full Length Anti-IL7R Recombinant Antibody Production and Modalities. (Creative Biolabs Original) Fig.5 Full Length Anti-IL7R Recombinant Antibody Production and Modalities.

Drug Information Targeting IL7R

Table 1. Therapeutic approaches targeting IL7R in clinical development.

Research phase Company Classification Indications Details
Phase II Bristol-Myers Squibb Human Monoclonal Antibodies Alopecia areata; Atopic dermatitis It is a fully human antagonistic antibody against IL-7Ralpha.
Phase II INSERM
OSE Immunotherapeutics
Humanized Monoclonal Antibodies Acute lymphocytic leukemia; Autoimmune disease; Inflammatory disorders This is a monoclonal antibody targeting the alpha subunit of the interleukin-7 receptor.
Phase I/II Medikine Cancer Immunotherapy
Fc Fusion Proteins
Polypeptides, from 41 AA
Cancer It is a Fc fusion protein comprising two agonistic synthetic peptides specific for interleukin-7 receptor (IL-7R), fused to human IgG2 Fc domain.

For more information about our anti-IL7R recombinant antibody products or any inquiries, feel free to reach out us. Our expert team is dedicated to offering personalized support and professional guidance to meet your research needs. We are committed to ensuring a smooth experience, providing reliable solutions to help you achieve meaningful scientific results. Your success matters to us, and we are always ready to assist.

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