Recombinant Human Anti-human C3 Antibody (CAT#: MHH-142)
Recombinant Human Antibody shows specific binding activity against Human C3, expressed in HEK 293 cells. Expressed as the combination of a heavy chain (HC) containing VH from anti-C3 mAb and CH1-3 region of human IgG1 and a light chain (LC) encoding VL from anti-C3 mAb and CL of human kappa light chain. Exists as a disulfide linked dimer of the HC and LC hetero-dimer under non-reducing condition.
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Normal Tissue
RNA Expression
Figure 1 Kidney
(Cells in glomeruli
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Proximal tubules (cell body)
Staining: Medium
Intensity: Moderate
Quantity:>75%
Proximal tubules (microvilli)
Staining: Medium
Intensity: Moderate)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/3563/10702_A_9_5.jpg
(Cells in glomeruli
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Proximal tubules (cell body)
Staining: Medium
Intensity: Moderate
Quantity:>75%
Proximal tubules (microvilli)
Staining: Medium
Intensity: Moderate)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/3563/10702_A_9_5.jpg
Figure 2 RNA cell line category: Group enriched (BJ hTERT+, EFO-21, Hep G2, HSkMC, SiHa)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000125730-C3
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000125730-C3
Specifications
- Immunogen
- Human complement component 3
- Host Species
- Human
- Derivation
- Human
- Type
- IgG
- Specificity
- Tested positive against native Human complement component 3
- Species Reactivity
- Human
- Applications
- Antibody assay: Enzyme-linked Immunosorbent Assay; Western blot; Immunoprecipitation; Functional Study
Product Property
- Purity
- >95% (SDS-PAGE)
- Storage
- Store at -20°C for long-term storage. Store at 4°C for up to one month. Avoid freeze/thaw cycles.
Target
- Alternative Names
- C3; complement component 3; ASP; C3a; C3b; AHUS5; ARMD9; CPAMD1; HEL-S-62p; complement C3; prepro-C3; C3a anaphylatoxin; complement component C3; complement component C3a; complement component C3b; acylation-stimulating protein cleavage product; epididymi
- Gene ID
- 718
- UniProt ID
- P01024
Related Resources
Systemic Lupus Erythematosus
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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IHC Kit and Antibody Products: Precision Tools for Immunohistochemistry
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHH-142-F(E) | Recombinant Human Anti-human C3 Antibody Fab Fragment | ELISA, WB, IP, FuncS | Fab |
| HPAB-0062-FY-F(E) | Human Anti-C3 Recombinant Antibody (clone MOR09611); Fab Fragment | ELISA | Human Fab |
| HPAB-0939LY-F(E) | Human Anti-C3 Recombinant Antibody (clone SS3-4); Fab Fragment | ELISA | Humanized Fab |
| HPAB-M0014-YC-F(E) | Mouse Anti-C3 Recombinant Antibody (clone cC3-4); Fab Fragment | ELISA, Neut | Mouse Fab |
| HPAB-M0015-YC-F(E) | Human Anti-C3 Recombinant Antibody (clone hC34); Fab Fragment | ELISA, Neut | Humanized Fab |
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