Recombinant Human Anti-human SIGLEC6 Antibody
CAT#: MHH-906
Recombinant Human Antibody recognizes and binds to Human SIGLEC6, expressed in HEK 293 cells. Expressed as the combination of a heavy chain (HC) containing VH from anti-SIGLEC6 mAb and CH1-3 region of human IgG1 and a light chain (LC) encoding VL from anti-SIGLEC6 mAb and CL of human kappa light chain. Exists as a disulfide linked dimer of the HC and LC hetero-dimer under non-reducing condition.
Gene Expression
Subcellular Location and Protein Expression
Figure 1 IF staining of human cell line HEL
Immunofluorescent staining of human cell line HEL shows localization to cytosol.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/8945/1847_E5_61_selected.jpg
Normal Tissue
Figure 2 Colon
Mucosal lymphoid cells
Staining: Medium
Intensity: Strong
Quantity: <25%
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/18198/148852_A_7_3.jpg
Normal Tissue
Figure 3 Kidney
Cells in tubules
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/18198/148852_A_9_5.jpg
Normal Tissue
Figure 4 Placenta
Syncytiotrophoblasts - cell body
Staining: High
Intensity: Strong
Quantity:>75%
Syncytiotrophoblasts - microvilli
Staining: Low
Intensity: Weak
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/18198/148852_A_2_7.jpg
RNA Expression
Figure 5 RNA cell line category: Cell line enriched (HMC-1)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000105492-SIGLEC6/subcellular
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Specifications
- Immunogen
- Human sialic acid binding Ig-like lectin 6
- Host Species
- Human
- Derivation
- Human
- Type
- IgG
- Specificity
- Tested positive against native Human sialic acid binding Ig-like lectin 6
- Species Reactivity
- Human
- Applications
- Formats of immunological tests: Radioimmunoassay; Immunoprecipitation; Functional Study
Product Property
- Purity
- Purity>95% by SDS-PAGE
- Storage
- 4°C, -20°C if preferred
Target
- Alternative Names
- SIGLEC6; sialic acid binding Ig-like lectin 6; CD327; CD33L; OBBP1; CD33L1; CD33L2; CDW327; sialic acid-binding Ig-like lectin 6; CD33 antigen-like 1; obesity-binding protein 1
- Gene ID
- 946
REVIEWS AND Q&AS
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Customer Review
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User-Friendly
It was straightforward to integrate this antibody into our protocols. The instructions were clear, and the overall user experience was hassle-free. It's accessible even for those relatively new to such research.
Dependable and Consistent
We've used this antibody across multiple projects, and its dependability is unmatched. Consistently does the job and has become a go-to for our SIGLEC6-related research activities.
High Purity for Clear Results
The>95% purity level ensures clear and concise results in our analyses. It's an effective and reliable antibody that has enhanced the accuracy of our experimental data.
Q&As
-
What is the target of this antibody?
A: This antibody specifically targets SIGLEC6, also known as CD327, a member of the sialic acid-binding immunoglobulin-like lectins family. It plays a role in cell signaling and immune response modulation.
-
What is the purity level of this antibody?
A: The antibody has a purity greater than 95%, ensuring its effectiveness and reliability in various assays.
-
How should I store this antibody?
A: This antibody should be stored at -20°C for long-term preservation. For short-term needs, storing it at 4°C is sufficient. Avoid repeated freeze-thaw cycles to maintain its integrity.
View the frequently asked questions answered by Creative Biolabs Support.
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Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "SIGLEC6"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-906 | Recombinant Anti-human SIGLEC6 Antibody | WB, FC, FuncS | IgG |
| HPAB-0076CQ | Mouse Anti-SIGLEC6 Recombinant Antibody (clone Mab239-90) | ELISA, FuncS, Inhib | Mouse IgG1, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-906-F(E) | Recombinant Anti-human SIGLEC6 Antibody Fab Fragment | FC, WB, FuncS | Fab |
| MHH-906-F(E) | Recombinant Human Anti-human SIGLEC6 Antibody Fab Fragment | ELISA, WB, Dot, FuncS | Fab |
| HPAB-0076CQ-F(E) | Mouse Anti-SIGLEC6 Recombinant Antibody (clone Mab239-90); Fab Fragment | ELISA, FuncS, Inhib | Mouse Fab, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-906-S(P) | Recombinant Anti-human SIGLEC6 Antibody scFv Fragment | WB, IF, FuncS | scFv |
| MHH-906-S(P) | Recombinant Human Anti-human SIGLEC6 Antibody scFv Fragment | WB, ELISA, IHC, FuncS | scFv |
| HPAB-0076CQ-S(P) | Mouse Anti-SIGLEC6 Recombinant Antibody (clone Mab239-90); scFv Fragment | ELISA, FuncS, Inhib | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-FY186 | Human Anti-SIGLEC6 (clone 239-90) scFv-Fc Chimera | IA | Human IgG1, scFv-Fc |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC645 | Recombinant Anti-SIGLEC6 Vesicular Antibody, EV Displayed (VS-0425-YC645) | ELISA, FC, Inhib, Cell-uptake |
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