Recombinant Human Anti-human SIGLEC6 Antibody (CAT#: MHH-906)
Recombinant Human Antibody recognizes and binds to Human SIGLEC6, expressed in HEK 293 cells. Expressed as the combination of a heavy chain (HC) containing VH from anti-SIGLEC6 mAb and CH1-3 region of human IgG1 and a light chain (LC) encoding VL from anti-SIGLEC6 mAb and CL of human kappa light chain. Exists as a disulfide linked dimer of the HC and LC hetero-dimer under non-reducing condition.
Specific Inquiry
Subcellular Location and Protein Expression
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line HEL
(Immunofluorescent staining of human cell line HEL shows localization to cytosol.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/8945/1847_E5_61_selected.jpg
(Immunofluorescent staining of human cell line HEL shows localization to cytosol.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/8945/1847_E5_61_selected.jpg
Figure 2 Colon
(Mucosal lymphoid cells
Staining: Medium
Intensity: Strong
Quantity: <25%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/18198/148852_A_7_3.jpg
(Mucosal lymphoid cells
Staining: Medium
Intensity: Strong
Quantity: <25%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/18198/148852_A_7_3.jpg
Figure 3 Kidney
(Cells in tubules
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/18198/148852_A_9_5.jpg
(Cells in tubules
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/18198/148852_A_9_5.jpg
Figure 4 Placenta
(Syncytiotrophoblasts - cell body
Staining: High
Intensity: Strong
Quantity:>75%
Syncytiotrophoblasts - microvilli
Staining: Low
Intensity: Weak)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/18198/148852_A_2_7.jpg
(Syncytiotrophoblasts - cell body
Staining: High
Intensity: Strong
Quantity:>75%
Syncytiotrophoblasts - microvilli
Staining: Low
Intensity: Weak)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/18198/148852_A_2_7.jpg
Figure 5 RNA cell line category: Cell line enriched (HMC-1)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000105492-SIGLEC6/subcellular
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000105492-SIGLEC6/subcellular
Specifications
- Immunogen
- Human sialic acid binding Ig-like lectin 6
- Host Species
- Human
- Derivation
- Human
- Type
- IgG
- Specificity
- Tested positive against native Human sialic acid binding Ig-like lectin 6
- Species Reactivity
- Human
- Applications
- Formats of immunological tests: Radioimmunoassay; Immunoprecipitation; Functional Study
Product Property
- Purity
- Purity>95% by SDS-PAGE
- Storage
- 4°C, -20°C if preferred
Target
- Alternative Names
- SIGLEC6; sialic acid binding Ig-like lectin 6; CD327; CD33L; OBBP1; CD33L1; CD33L2; CDW327; sialic acid-binding Ig-like lectin 6; CD33 antigen-like 1; obesity-binding protein 1
- Gene ID
- 946
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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ScFv-Fc Chimera Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-906 | Recombinant Anti-human SIGLEC6 Antibody | WB, FC, FuncS | IgG |
| HPAB-0076CQ | Mouse Anti-SIGLEC6 Recombinant Antibody (clone Mab239-90) | ELISA, FuncS, Inhib | Mouse IgG1, κ |
Customer Reviews and Q&As
Customer Review
Q&As
User-Friendly
It was straightforward to integrate this antibody into our protocols. The instructions were clear, and the overall user experience was hassle-free. It's accessible even for those relatively new to such research.
Dependable and Consistent
We've used this antibody across multiple projects, and its dependability is unmatched. Consistently does the job and has become a go-to for our SIGLEC6-related research activities.
High Purity for Clear Results
The>95% purity level ensures clear and concise results in our analyses. It's an effective and reliable antibody that has enhanced the accuracy of our experimental data.
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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