APC-A*02:01/Human RNF43 (ALWPWLLMAT) MHC Tetramer (CAT#: MHC-CN1186)

Specific Inquiry
  • Size:
  • Gene Expression
  • Datasheet
  • MSDS
  • COA
Normal Tissue
RNA Expression

Specifications

  • Allele
  • A*02:01
  • Class
  • Class I
  • MHC Species
  • Human
  • Antigen
  • RNF43
  • Antigen Species
  • Human
  • Peptide
  • ALWPWLLMAT
  • Conjugate
  • APC
  • Application
  • FCM, IHC

Target

  • Antigen Introduction
  • The protein encoded by this gene is a RING-type E3 ubiquitin ligase and is predicted to contain a transmembrane domain, a protease-associated domain, an ectodomain, and a cytoplasmic RING domain. This protein is thought to negatively regulate Wnt signaling, and expression of this gene results in an increase in ubiquitination of frizzled receptors, an alteration in their subcellular distribution, resulting in reduced surface levels of these receptors. Mutations in this gene have been reported in multiple tumor cells, including colorectal and endometrial cancers. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Mar 2015]
  • Alternative Names
  • Ring Finger Protein 43; RING-Type E3 Ubiquitin Transferase RNF43; RING Finger Protein 43; E3 Ubiquitin-Protein Ligase RNF43; EC 2.3.2.27; RNF124; SSPCS; URCC;

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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