FITC-A*03:01/Human PMEL (ALLAVGATK) MHC Tetramer

CAT#: MHC-CN1143

Gene Expression
Figure 1 IF staining of human cell line SK-MEL-30 Figure 2 Kidney Figure 3 Testis Figure 4 Skin Figure 5 RNA cell line category: Cell line enriched (SK-MEL-30)

Specifications

  • Allele
  • A*03:01
  • Class
  • Class I
  • MHC Species
  • Human
  • Antigen
  • PMEL
  • Antigen Species
  • Human
  • Peptide
  • ALLAVGATK
  • Conjugate
  • FITC

Target

  • Antigen Introduction
  • This gene encodes a melanocyte-specific type I transmembrane glycoprotein. The encoded protein is enriched in melanosomes, which are the melanin-producing organelles in melanocytes, and plays an essential role in the structural organization of premelanosomes. This protein is involved in generating internal matrix fibers that define the transition from Stage I to Stage II melanosomes. This protein undergoes a complex pattern of prosttranslational processing and modification that is essential to the proper functioning of the protein. A secreted form of this protein that is released by proteolytic ectodomain shedding may be used as a melanoma-specific serum marker. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2011]
  • Alternative Names
  • PMEL; Melanocyte protein Pmel 17 precursor; P1; SI; SIL; ME20; P100; SILV
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Protocol & Troubleshooting

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