FITC-A*03:01/Human PMEL (ALLAVGATK) MHC Tetramer
CAT#: MHC-CN1143
Gene Expression
Subcellular Location and Protein Expression
Figure 1 IF staining of human cell line SK-MEL-30
Immunofluorescent staining of human cell line SK-MEL-30 shows localization to endoplasmic reticulum & the Golgi apparatus.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/31649/1898_C6_19_cr5ba8a6f6e250d_selected.jpg
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Specifications
- Allele
- A*03:01
- Class
- Class I
- MHC Species
- Human
- Antigen
- PMEL
- Antigen Species
- Human
- Peptide
- ALLAVGATK
- Conjugate
- FITC
- Application
- FCM, IHC
Target
- Antigen Introduction
- This gene encodes a melanocyte-specific type I transmembrane glycoprotein. The encoded protein is enriched in melanosomes, which are the melanin-producing organelles in melanocytes, and plays an essential role in the structural organization of premelanosomes. This protein is involved in generating internal matrix fibers that define the transition from Stage I to Stage II melanosomes. This protein undergoes a complex pattern of prosttranslational processing and modification that is essential to the proper functioning of the protein. A secreted form of this protein that is released by proteolytic ectodomain shedding may be used as a melanoma-specific serum marker. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2011]
- Alternative Names
- PMEL; Melanocyte protein Pmel 17 precursor; P1; SI; SIL; ME20; P100; SILV
- Gene ID
- 6490
- UniProt ID
- P40967
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Datasheet
MSDS
COA
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Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1280z | Mouse Anti-PMEL Recombinant Antibody (clone 21C9) | ICC, IF, IHC | Mouse IgG1 |
| HPAB-0046-LSX | Mouse Anti-PMEL Recombinant Antibody (HPAB-0046-LSX) | ELISA, WB, FC, IB, IF | Mouse Fab |
| HPAB-0047-LSX | Human Anti-PMEL Recombinant Antibody (HPAB-0047-LSX) | ELISA, WB, FC | Human IgG |
| VS3-CJ934 | Mouse Anti-PMEL Recombinant Antibody (clone PT1593) | IHC-P | Mouse IgG2b, κ |
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| AGTO-G051E | Anti-PMEL immunotoxin (Fab)-PE | Cytotoxicity assay, Function study |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-1047CL-F(E) | Anti-Human PMEL Recombinant Antibody Fab Fragment (A3F) | IHC, WB, FC | |
| TAB-1048CL-F(E) | Anti-Human PMEL Recombinant Antibody Fab Fragment (G11B) | IHC, WB, FC | |
| TAB-1049CL-F(E) | Anti-Human PMEL Recombinant Antibody Fab Fragment (J7E) | IHC, WB, FC | |
| TAB-1050CL-F(E) | Mouse Anti-PMEL Recombinant Antibody; Fab Fragment (TAB-1050CL-F(E)) | FC | Mouse Fab |
| TAB-1051CL-F(E) | Mouse Anti-PMEL Recombinant Antibody; Fab Fragment (TAB-1051CL-F(E)) | FC | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-2761 | Hi-Affi™ Recombinant Rabbit Anti-PMEL Monoclonal Antibody (DS2761AB) | IHC-P | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0046-LSX-S(P) | Mouse Anti-PMEL Recombinant Antibody; scFv Fragment (HPAB-0046-LSX-S(P)) | ELISA, WB, FC | Mouse scFv |
| HPAB-0047-LSX-S(P) | Mouse Anti-PMEL Recombinant Antibody; scFv Fragment (HPAB-0047-LSX-S(P)) | ELISA, WB, FC | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0046-LSX-F(E) | Mouse Anti-PMEL Recombinant Antibody; Fab Fragment (HPAB-0046-LSX-F(E)) | ELISA, WB, FC | Mouse Fab |
| HPAB-0047-LSX-F(E) | Human Anti-PMEL Recombinant Antibody; Fab Fragment (HPAB-0047-LSX-F(E)) | ELISA, WB, FC | Chimeric Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-YF186 | H-2Db/HPV16 E7 (RAHYNIVTF) MHC Monomer | MHC Multimer | |
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| MHC-YF225 | A*02:01/HPV16 E7 (YMLDLQPET) MHC Monomer | MHC Multimer | |
| MHC-YF295 | A*02:01/HPV E7 (YMLDLQPETT) MHC Monomer | MHC Multimer |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC658 | Recombinant Anti-PMEL Vesicular Antibody, EV Displayed (VS-0425-YC658) | ELISA, FC, Cell-uptake |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY5512 | Anti-PMEL Immunohistochemistry Kit | IHC | |
| VS-0525-XY5513 | Anti-Mouse PMEL Immunohistochemistry Kit | IHC | |
| VS-0525-XY5514 | Anti-Rat PMEL Immunohistochemistry Kit | IHC |
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