PMEL
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Loading...- APC-A*02:01/Human gp100 (YLEPGPVTA) MHC Tetramer (MHC-LC142)
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- Class: Class I
- Antigen: gp100
- Antigen Species: Human
- Peptide: YLEPGPVTA
- Conjugate: APC
- PE-H-2Db/Human gp100 (KVPRNQDWL) MHC Tetramer (MHC-LC201)
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- Class: Class I
- Antigen: Human gp100
- Antigen Species: Human
- Peptide: KVPRNQDWL
- Conjugate: PE
- APC-H-2Db/Human gp100 (KVPRNQDWL) MHC Tetramer (MHC-LC202)
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- Class: Class I
- Antigen: Human gp100
- Antigen Species: Human
- Peptide: KVPRNQDWL
- Conjugate: APC
- PE-A*11:01/Human PMEL (GTATLRLVK) MHC Tetramer (MHC-LC3009)
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- Class: Class I
- Antigen: PMEL
- Antigen Species: Human
- Peptide: GTATLRLVK
- Conjugate: PE
- PE-A*03:01/Human PMEL (HTMEVTVYHR) MHC Tetramer (MHC-LC3011)
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- Class: Class I
- Antigen: PMEL
- Antigen Species: Human
- Peptide: HTMEVTVYHR
- Conjugate: PE
- PE-B*07:02/Human PMEL (LPHSSSHWL) MHC Tetramer (MHC-LC3016)
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- Class: Class I
- Antigen: PMEL
- Antigen Species: Human
- Peptide: LPHSSSHWL
- Conjugate: PE
- A*0201/Human gp100 (IMDQVPFSV) MHC Tetramer (MHC-LC775)
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- Class: Class I
- Antigen: gp100
- Antigen Species: Human
- Peptide: IMDQVPFSV
- PE-A*11:01/Human PMEL (SSSHWLRLPR) MHC Tetramer (MHC-LC3026)
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- Class: Class I
- Antigen: PMEL
- Antigen Species: Human
- Peptide: SSSHWLRLPR
- Conjugate: PE
- A*0201/Human gp100 (VLYRYGSFSV) MHC Tetramer (MHC-LC776)
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- Class: Class I
- Antigen: gp100
- Antigen Species: Human
- Peptide: VLYRYGSFSV
- PE-A*03:01/Human PMEL (VVLASLIYR) MHC Tetramer (MHC-LC3027)
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- Class: Class I
- Antigen: PMEL
- Antigen Species: Human
- Peptide: VVLASLIYR
- Conjugate: PE
- PE-A*02:01/Human PMEL (YLAPGPVTA) MHC Tetramer (MHC-LC929)
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- Class: Class I
- Antigen: gp100
- Antigen Species: Human
- Peptide: YLAPGPVTA
- Conjugate: PE
- PE-A*02:01/Human PMEL (YLEPAPVTA) MHC Tetramer (MHC-LC932)
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- Class: Class I
- Antigen: gp100
- Antigen Species: Human
- Peptide: YLEPAPVTA
- Conjugate: PE
- PE-A*11:01/Human PMEL (VVLASLIYR) MHC Tetramer (MHC-LC3028)
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- Class: Class I
- Antigen: PMEL
- Antigen Species: Human
- Peptide: VVLASLIYR
- Conjugate: PE
- PE-A*02:01/Human PMEL (YLEPGPVTV) MHC Tetramer (MHC-LC935)
-
- Class: Class I
- Antigen: gp100
- Antigen Species: Human
- Peptide: YLEPGPVTV
- Conjugate: PE
- PE-A*03:01/Human PMEL (VVLASLIYRR) MHC Tetramer (MHC-LC3029)
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- Class: Class I
- Antigen: PMEL
- Antigen Species: Human
- Peptide: VVLASLIYRR
- Conjugate: PE
- APC-A*02:01/Human PMEL (AMLGTHTMEV) MHC Tetramer (MHC-LC2904)
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- Class: Class I
- Antigen: PMEL
- Antigen Species: Human
- Peptide: AMLGTHTMEV
- Conjugate: APC
- PE-A*11:01/Human PMEL (VVLASLIYRR) MHC Tetramer (MHC-LC3030)
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- Class: Class I
- Antigen: PMEL
- Antigen Species: Human
- Peptide: VVLASLIYRR
- Conjugate: PE
- A*0201/Human gp100 (ITDQVPFSV) MHC Tetramer (MHC-LC774)
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- Class: Class I
- Antigen: gp100
- Antigen Species: Human
- Peptide: ITDQVPFSV
- H-2Db Mouse gp100 (EGSRNQDWL) MHC Tetramer (MHC-LC211)
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- Class: Class I
- Antigen: Mouse gp100
- Antigen Species: Mouse
- Peptide: EGSRNQDWL
- Conjugate: APC
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- Class: Class II
- Antigen: gp100
- Antigen Species: Human
- Peptide: WNRQLYPEWTEAQRLD
- Conjugate: BV421
- PE-A*02:01/Human PMEL (KTWGQYWQV) MHC Tetramer (MHC-LC2223)
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- Class: Class I
- Antigen: PMEL
- Antigen Species: Human
- Peptide: KTWGQYWQV
- Conjugate: PE
- PE-A*02:01/Human PMEL (KTWGQYWQVL) MHC Tetramer (MHC-LC2224)
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- Class: Class I
- Antigen: PMEL
- Antigen Species: Human
- Peptide: KTWGQYWQVL
- Conjugate: PE
- PE-A*02:01/Human PMEL (LLDGTATLRL) MHC Tetramer (MHC-LC2225)
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- Class: Class I
- Antigen: PMEL
- Antigen Species: Human
- Peptide: LLDGTATLRL
- Conjugate: PE
- PE-A*02:01/Human PMEL (TITDQVPFSV) MHC Tetramer (MHC-LC2227)
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- Class: Class I
- Antigen: PMEL
- Antigen Species: Human
- Peptide: TITDQVPFSV
- Conjugate: PE
- PE-A*02:01/Human PMEL (VLYRYGSFSV) MHC Tetramer (MHC-LC2228)
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- Class: Class I
- Antigen: PMEL
- Antigen Species: Human
- Peptide: VLYRYGSFSV
- Conjugate: PE
- PE-A*02:01/Human PMEL (YLEPGPVTA) MHC Tetramer (MHC-LC2229)
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- Class: Class I
- Antigen: PMEL
- Antigen Species: Human
- Peptide: YLEPGPVTA
- Conjugate: PE
- Mouse Anti-PMEL Antibody (clone G11B), mRNA (TAB-1048CL-mRNA)
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- Species Reactivity: Human
- Mouse Anti-PMEL Antibody (clone J7E), mRNA (TAB-1049CL-mRNA)
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- Species Reactivity: Human
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- Species Reactivity: Human
- Epitope: KTWGQYWQV
- MHC: HLA-A*0201
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- Species Reactivity: Human
- Epitope: KTWGQYWQV
- MHC: HLA-A*0201
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- Class: Class I
- Antigen: gp100-intron 4
- Antigen Species: Human
- Peptide: VYFFLPDHL
- Conjugate: PE
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- Class: Class I
- Antigen: gp100-intron 4
- Antigen Species: Human
- Peptide: VYFFLPDHL
- Conjugate: APC
- H-2Db/Human Mouse gp100 (EGSRNQDWL) MHC Tetramer (MHC-LC210)
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- Class: Class I
- Antigen: Mouse gp100
- Antigen Species: Human
- Peptide: EGSRNQDWL
- Conjugate: PE
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- Class: Class I
- Antigen: gp100
- Antigen Species: Human
- Peptide: YLEPAPVTA
- Conjugate: BV421
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- Class: Class I
- Antigen: gp100
- Antigen Species: Human
- Peptide: YLEPGPVTV
- Conjugate: BV421
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1
- Application: ICC, IF, IHC
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- Species Reactivity: Human
- Type: ADCC enhanced antibody
- H-2Db/Human gp100 (KVPRNQDWL) MHC Tetramer (MHC-LC099)
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- Class: Class I
- Antigen: gp100
- Antigen Species: Human
- Peptide: KVPRNQDWL
- Conjugate: BV421
- APC-A*02:01/Human PMEL (YLAPGPVTA) MHC Tetramer (MHC-LC930)
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- Class: Class I
- Antigen: gp100
- Antigen Species: Human
- Peptide: YLAPGPVTA
- Conjugate: APC
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- Class: Class I
- Antigen: gp100
- Antigen Species: Human
- Peptide: YLAPGPVTA
- Conjugate: BV421
- PE-A*03:01/Human PMEL (ALLAVGATK) MHC Tetramer (MHC-LC2842)
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- Class: Class I
- Antigen: PMEL
- Antigen Species: Human
- Peptide: ALLAVGATK
- Conjugate: PE
- APC-A*02:01/Human PMEL (ITDQVPFSV) MHC Tetramer (MHC-LC2457)
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- Class: Class I
- Antigen: PMEL
- Antigen Species: Human
- Peptide: ITDQVPFSV
- Conjugate: APC
- APC-A*02:01/Human PMEL (YLEPGPVTA) MHC Tetramer (MHC-LC2458)
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- Class: Class I
- Antigen: PMEL
- Antigen Species: Human
- Peptide: YLEPGPVTA
- Conjugate: APC
- PE-B*07:02/Human PMEL (EPGPVTAQV) MHC Tetramer (MHC-LC2467)
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- Class: Class I
- Antigen: PMEL
- Antigen Species: Human
- Peptide: EPGPVTAQV
- Conjugate: PE
- APC-A*02:01/Human PMEL (YLEPAPVTA) MHC Tetramer (MHC-LC933)
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- Class: Class I
- Antigen: gp100
- Antigen Species: Human
- Peptide: YLEPAPVTA
- Conjugate: APC
- PE-A*11:01/Human PMEL (ALLAVGATK) MHC Tetramer (MHC-LC2843)
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- Class: Class I
- Antigen: PMEL
- Antigen Species: Human
- Peptide: ALLAVGATK
- Conjugate: PE
- APC-A*02:01/Human PMEL (YLEPGPVTV) MHC Tetramer (MHC-LC936)
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- Class: Class I
- Antigen: gp100
- Antigen Species: Human
- Peptide: YLEPGPVTV
- Conjugate: APC
- PE-B*51:01/Human PMEL (EPGPVTAQV) MHC Tetramer (MHC-LC2468)
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- Class: Class I
- Antigen: PMEL
- Antigen Species: Human
- Peptide: EPGPVTAQV
- Conjugate: PE
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- Species Reactivity: Human
- Type: Mouse antibody
- Application: IHC
- PE-A*31:01/Human PMEL (ALLAVGATK) MHC Tetramer (MHC-LC2844)
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- Class: Class I
- Antigen: PMEL
- Antigen Species: Human
- Peptide: ALLAVGATK
- Conjugate: PE
- PE-A*68:01/Human PMEL (ALLAVGATK) MHC Tetramer (MHC-LC2845)
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- Class: Class I
- Antigen: PMEL
- Antigen Species: Human
- Peptide: ALLAVGATK
- Conjugate: PE
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- Class: Class II
- Antigen: gp100
- Antigen Species: Human
- Peptide: WNRQLYPEWTEAQRLD
- Conjugate: APC
- PE-A*03:01/Human PMEL (ALNFPGSQK) MHC Tetramer (MHC-LC2846)
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- Class: Class I
- Antigen: PMEL
- Antigen Species: Human
- Peptide: ALNFPGSQK
- Conjugate: PE
- PE-B*07:02/Human PMEL (TPAEVSIVV) MHC Tetramer (MHC-LC2544)
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- Class: Class I
- Antigen: PMEL
- Antigen Species: Human
- Peptide: TPAEVSIVV
- Conjugate: PE
- PE-B*35:01/Human PMEL (TPAEVSIVV) MHC Tetramer (MHC-LC2545)
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- Class: Class I
- Antigen: PMEL
- Antigen Species: Human
- Peptide: TPAEVSIVV
- Conjugate: PE
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- Class: Class II
- Antigen: PMEL
- Antigen Species: Human
- Peptide: EGDAFELTVSCQGGLPK
- Conjugate: PE
- PE-B*51:01/Human PMEL (TPAEVSIVV) MHC Tetramer (MHC-LC2546)
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- Class: Class I
- Antigen: PMEL
- Antigen Species: Human
- Peptide: TPAEVSIVV
- Conjugate: PE
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- Class: Class II
- Antigen: PMEL
- Antigen Species: Human
- Peptide: EGDAFELTVSCQGGLPK
- Conjugate: PE
- PE-B*54:01/Human PMEL (TPAEVSIVV) MHC Tetramer (MHC-LC2547)
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- Class: Class I
- Antigen: PMEL
- Antigen Species: Human
- Peptide: TPAEVSIVV
- Conjugate: PE
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- Class: Class II
- Antigen: PMEL
- Antigen Species: Human
- Peptide: EKVPVSEVMGTTLAEMSTPEAT
- Conjugate: PE
- PE-B*07:02/Human PMEL (VPLAHSSSA) MHC Tetramer (MHC-LC2560)
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- Class: Class I
- Antigen: PMEL
- Antigen Species: Human
- Peptide: VPLAHSSSA
- Conjugate: PE
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- Class: Class II
- Antigen: PMEL
- Antigen Species: Human
- Peptide: EKVPVSEVMGTTLAEMSTPEAT
- Conjugate: PE
- PE-B*51:01/Human PMEL (VPLAHSSSA) MHC Tetramer (MHC-LC2561)
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- Class: Class I
- Antigen: PMEL
- Antigen Species: Human
- Peptide: VPLAHSSSA
- Conjugate: PE
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- Class: Class II
- Antigen: PMEL
- Antigen Species: Human
- Peptide: IYRRRLMKQDFSVPQLPHS
- Conjugate: PE
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- Class: Class II
- Antigen: PMEL
- Antigen Species: Human
- Peptide: IYRRRLMKQDFSVPQLPHS
- Conjugate: PE
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- Class: Class II
- Antigen: PMEL
- Antigen Species: Human
- Peptide: KRCLLHLAVIGALLAVGATKV
- Conjugate: PE
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- Class: Class II
- Antigen: PMEL
- Antigen Species: Human
- Peptide: LCQPVLPSPACQLVLHQILKGG
- Conjugate: PE
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- Class: Class II
- Antigen: PMEL
- Antigen Species: Human
- Peptide: MTPAEVSIVVLSGTTAAQVTTT
- Conjugate: PE
-
- Class: Class II
- Antigen: PMEL
- Antigen Species: Human
- Peptide: MTPAEVSIVVLSGTTAAQVTTT
- Conjugate: PE
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- Class: Class II
- Antigen: PMEL
- Antigen Species: Human
- Peptide: PGPVTAQVVLQAAIPLTSCGSS
- Conjugate: PE
-
- Class: Class II
- Antigen: PMEL
- Antigen Species: Human
- Peptide: PGPVTAQVVLQAAIPLTSCGSS
- Conjugate: PE
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- Class: Class I
- Antigen: gp100 (mutant)
- Antigen Species: Human
- Peptide: IMDQVPFSV
- Conjugate: PE
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- Class: Class I
- Antigen: gp100 (mutant)
- Antigen Species: Human
- Peptide: IMDQVPFSV
- Conjugate: APC
- PE-A*02:01/Human gp100 (ITDQVPFSV) MHC Tetramer (MHC-LC102)
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- Class: Class I
- Antigen: gp100
- Antigen Species: Human
- Peptide: ITDQVPFSV
- Conjugate: PE
- APC-A*02:01/Human gp100 (ITDQVPFSV) MHC Tetramer (MHC-LC103)
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- Class: Class I
- Antigen: gp100
- Antigen Species: Human
- Peptide: ITDQVPFSV
- Conjugate: APC
- PE-A*02:01/Human gp100 (KTWGQYWQV) MHC Tetramer (MHC-LC104)
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- Class: Class I
- Antigen: gp100
- Antigen Species: Human
- Peptide: KTWGQYWQV
- Conjugate: PE
- APC-A*02:01/Human gp100 (KTWGQYWQV) MHC Tetramer (MHC-LC105)
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- Class: Class I
- Antigen: gp100
- Antigen Species: Human
- Peptide: KTWGQYWQV
- Conjugate: APC
- PE-A*02:01/Human gp100 (YLEPGPVTA) MHC Tetramer (MHC-LC141)
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- Class: Class I
- Antigen: gp100
- Antigen Species: Human
- Peptide: YLEPGPVTA
- Conjugate: PE
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- Species Reactivity: Human
- Type: Antibody
- Anti-PMEL immunotoxin (Fab)-PE (AGTO-G051E)
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- Species Reactivity: Human
- Application: Cytotoxicity assay, Function study
- Anti-Human PMEL Recombinant Antibody (A3F) (TAB-1047CL)
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- Application: WB
- Anti-Human PMEL Recombinant Antibody Fab Fragment (A3F) (TAB-1047CL-F(E))
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- Application: IHC, WB, FC
- Anti-Human PMEL Recombinant Antibody scFv Fragment (A3F) (TAB-1047CL-S(P))
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- Application: IHC, WB, FC
- Anti-Human PMEL Recombinant Antibody scFv Fragment (G11B) (TAB-1048CL-S(P))
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- Application: IHC, WB, FC
- Anti-Human PMEL Recombinant Antibody (G11B) (TAB-1048CL)
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- Application: WB, FC, IHC
- Anti-Human PMEL Recombinant Antibody (J7E) (TAB-1049CL)
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- Application: WB
- Anti-Human PMEL Recombinant Antibody Fab Fragment (G11B) (TAB-1048CL-F(E))
-
- Application: IHC, WB, FC
- Anti-Human PMEL Recombinant Antibody Fab Fragment (J7E) (TAB-1049CL-F(E))
-
- Application: IHC, WB, FC
- Mouse Anti-PMEL Recombinant Antibody (TAB-1050CL) (TAB-1050CL)
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- Species Reactivity: Cynomolgus monkey, rat, and mouse
- Type: Mouse IgG
- Application: FC, FuncS
- Mouse Anti-PMEL Recombinant Antibody (TAB-1051CL) (TAB-1051CL)
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: FC
- Mouse Anti-PMEL Recombinant Antibody (TAB-1052CL) (TAB-1052CL)
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: FC
- Mouse Anti-PMEL Recombinant Antibody; Fab Fragment (TAB-1051CL-F(E)) (TAB-1051CL-F(E))
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- Species Reactivity: Human
- Type: Mouse Fab
- Application: FC
- Mouse Anti-PMEL Recombinant Antibody; Fab Fragment (TAB-1052CL-F(E)) (TAB-1052CL-F(E))
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- Species Reactivity: Human
- Type: Mouse Fab
- Application: FC
- Mouse Anti-PMEL Recombinant Antibody; Fab Fragment (TAB-1050CL-F(E)) (TAB-1050CL-F(E))
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- Species Reactivity: Cynomolgus monkey, rat, and mouse
- Type: Mouse Fab
- Application: FC
- Anti-Human PMEL Recombinant Antibody scFv Fragment (J7E) (TAB-1049CL-S(P))
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- Application: IHC, WB, FC
- Mouse Anti-PMEL Recombinant Antibody; scFv Fragment (TAB-1050CL-S(P)) (TAB-1050CL-S(P))
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- Species Reactivity: Cynomolgus monkey, rat, and mouse
- Type: Mouse scFv
- Application: FC
- Mouse Anti-PMEL Recombinant Antibody; scFv Fragment (TAB-1051CL-S(P)) (TAB-1051CL-S(P))
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: FC
- Mouse Anti-PMEL Recombinant Antibody; scFv Fragment (TAB-1052CL-S(P)) (TAB-1052CL-S(P))
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: FC
- Anti-PMEL17 (31D1.6.7)-mc-vc-MMAE ADC (ADC-150LCT)
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- Target: PMEL17
- Linker: mc-VC (maleimidocaproyl-valine-citrulline)
- Drug: MMAE (Monomethyl auristatin E)
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- Derivation: Phage display library screening
- Type: IgG
- Application: IHC-P
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For Research Use Only. Not For Clinical Use.
Background
This gene encodes a melanocyte-specific type I transmembrane glycoprotein. The encoded protein is enriched in melanosomes, which are the melanin-producing organelles in melanocytes, and plays an essential role in the structural organization of premelanosomes. This protein is involved in generating internal matrix fibers that define the transition from Stage I to Stage II melanosomes. This protein undergoes a complex pattern of prosttranslational processing and modification that is essential to the proper functioning of the protein. A secreted form of this protein that is released by proteolytic ectodomain shedding may be used as a melanoma-specific serum marker.

