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PMEL
This gene encodes a melanocyte-specific type I transmembrane glycoprotein. The encoded protein is enriched in melanosomes, which are the melanin-producing organelles in melanocytes, and plays an essential role in the structural organization of premelanosomes. This protein is involved in generating internal matrix fibers that define the transition from Stage I to Stage II melanosomes. This protein undergoes a complex pattern of prosttranslational processing and modification that is essential to the proper functioning of the protein. A secreted form of this protein that is released by proteolytic ectodomain shedding may be used as a melanoma-specific serum marker. Alternate splicing results in multiple transcript variants.
Anti-Human PMEL Therapeutic Antibody scFv Fragment (J7E) (TAB-1049CL-S(P))
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- Application: IHC, WB, FC
Anti-Human PMEL Therapeutic Antibody scFv Fragment (G11B) (TAB-1048CL-S(P))
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- Application: IHC, WB, FC
Anti-Human PMEL Therapeutic Antibody scFv Fragment (A3F) (TAB-1047CL-S(P))
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- Application: IHC, WB, FC
Anti-PMEL immunotoxin (Fab)-PE (AGTO-G051E)
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- Species Reactivity: Human
- Application: Cytotoxicity assay, Function study
Recombinant Anti-Human PMEL VHH Single Domain Antibody (NAB-1938-sdAb)
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- Species Reactivity: Human
- Type: Llama VHH
- Application: WB, ICC, ChiP, FA, ELISA
Anti-Human PMEL Therapeutic Antibody (8G3) (TAB-1051CL)
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- Application: FC
Anti-Human PMEL Therapeutic Antibody (17A9) (TAB-1050CL)
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- Species Reactivity: Cynomolgus monkey, rat, and mouse
- Application: FC
Anti-Human PMEL Therapeutic Antibody (J7E) (TAB-1049CL)
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- Application: IHC, WB, FC
Anti-Human PMEL Therapeutic Antibody (G11B) (TAB-1048CL)
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- Application: IHC, WB, FC
Anti-Human PMEL Therapeutic Antibody (A3F) (TAB-1047CL)
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- Application: IHC, WB, FC
Afuco™ Anti-Human PMEL ADCC Theraputic Antibody, ADCC Enhanced (AFC-700CL)
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- Species Reactivity: Human
- Type: ADCC enhanced antibody
Recombinant Anti-Human PMEL Antibody scFv Fragment (MOB-1280z-S(P))
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- Derivation: Mouse
- Species Reactivity: Human
- Type: scFv
- Application: FC, RIA, Biosensors, FuncS
Recombinant Anti-Human PMEL Antibody Fab Fragment (MOB-1280z-F(E))
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Fab
- Application: ELISA, FacS, FuncS
Recombinant Anti-Human PMEL Antibody (MOB-1280z)
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- Derivation: Mouse
- Species Reactivity: Human
- Type: IgG
- Application: WB, Dot, FuncS
Anti-Human PMEL Therapeutic Antibody scFv Fragment (15F2) (TAB-1052CL-S(P))
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- Application: FC
Anti-Human PMEL Therapeutic Antibody scFv Fragment (8G3) (TAB-1051CL-S(P))
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- Application: FC
Anti-Human PMEL Therapeutic Antibody scFv Fragment (17A9) (TAB-1050CL-S(P))
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- Species Reactivity: Cynomolgus monkey, rat, and mouse
- Application: FC
Anti-Human PMEL Therapeutic Antibody Fab Fragment (17A9) (TAB-1050CL-F(E))
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- Species Reactivity: Cynomolgus monkey, rat, and mouse
- Application: FC
Anti-Human PMEL Therapeutic Antibody Fab Fragment (J7E) (TAB-1049CL-F(E))
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- Application: IHC, WB, FC
Anti-Human PMEL Therapeutic Antibody Fab Fragment (G11B) (TAB-1048CL-F(E))
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- Application: IHC, WB, FC
Anti-Human PMEL Therapeutic Antibody Fab Fragment (A3F) (TAB-1047CL-F(E))
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- Application: IHC, WB, FC
Recombinant Mouse Anti-Human PMEL Antibody (clone IMB46) (MOB-0325MZ)
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- Species Reactivity: Human
- Type: Mouse antibody
- Application: IHC
Anti-Human PMEL Therapeutic Antibody (15F2) (TAB-1052CL)
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- Application: FC
Anti-Human PMEL Therapeutical Antibody (TAB-728CL)
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- Species Reactivity: Human
- Type: Antibody
Anti-Human PMEL Therapeutic Antibody Fab Fragment (15F2) (TAB-1052CL-F(E))
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- Application: FC
Anti-Human PMEL Therapeutic Antibody Fab Fragment (8G3) (TAB-1051CL-F(E))
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- Application: FC
Hi-Affi™ Recombinant Rabbit Anti-PMEL Monoclonal Antibody (DS2761AB) (MOR-2761)
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- Derivation: Phage display library screening
- Type: IgG
- Application: IHC-P
A*0201/Human gp100 (ITDQVPFSV) MHC Tetramer (MHC-LC774)
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- Class: Class I
- Target: gp100
- Specificity: Human
- Peptide: ITDQVPFSV
H-2Db/Human Mouse gp100 (EGSRNQDWL) MHC Tetramer (MHC-LC211)
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- Class: Class I
- Target: Mouse gp100
- Specificity: Human
- Peptide: EGSRNQDWL
- Conjugate: APC
H-2Db/Human Mouse gp100 (EGSRNQDWL) MHC Tetramer (MHC-LC210)
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- Class: Class I
- Target: Mouse gp100
- Specificity: Human
- Peptide: EGSRNQDWL
- Conjugate: PE
H-2Db/Human Human gp100 (KVPRNQDWL) MHC Tetramer (MHC-LC202)
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- Class: Class I
- Target: Human gp100
- Specificity: Human
- Peptide: KVPRNQDWL
- Conjugate: APC
H-2Db/Human Human gp100 (KVPRNQDWL) MHC Tetramer (MHC-LC201)
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- Class: Class I
- Target: Human gp100
- Specificity: Human
- Peptide: KVPRNQDWL
- Conjugate: PE
PE-A*02:01/Human PMEL (YLEPGPVTV) MHC Tetramer (MHC-LC935)
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- Class: Class I
- Target: gp100
- Specificity: Human
- Peptide: YLEPGPVTV
- Conjugate: PE
PE-A*02:01/Human PMEL (YLEPAPVTA) MHC Tetramer (MHC-LC932)
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- Class: Class I
- Target: gp100
- Specificity: Human
- Peptide: YLEPAPVTA
- Conjugate: PE
PE-A*02:01/Human PMEL (YLAPGPVTA) MHC Tetramer (MHC-LC929)
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- Class: Class I
- Target: gp100
- Specificity: Human
- Peptide: YLAPGPVTA
- Conjugate: PE
A*0201/Human gp100 (VLYRYGSFSV) MHC Tetramer (MHC-LC776)
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- Class: Class I
- Target: gp100
- Specificity: Human
- Peptide: VLYRYGSFSV
A*0201/Human gp100 (IMDQVPFSV) MHC Tetramer (MHC-LC775)
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- Class: Class I
- Target: gp100
- Specificity: Human
- Peptide: IMDQVPFSV
A*02:01/Human gp100 (YLEPGPVTA) MHC Tetramer (MHC-LC141)
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- Class: Class I
- Target: gp100
- Specificity: Human
- Peptide: YLEPGPVTA
- Conjugate: PE
A*02:01/Human gp100 (KTWGQYWQV) MHC Tetramer (MHC-LC105)
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- Class: Class I
- Target: gp100
- Specificity: Human
- Peptide: KTWGQYWQV
- Conjugate: APC
A*02:01/Human gp100 (KTWGQYWQV) MHC Tetramer (MHC-LC104)
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- Class: Class I
- Target: gp100
- Specificity: Human
- Peptide: KTWGQYWQV
- Conjugate: PE
A*02:01/Human gp100 (ITDQVPFSV) MHC Tetramer (MHC-LC103)
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- Class: Class I
- Target: gp100
- Specificity: Human
- Peptide: ITDQVPFSV
- Conjugate: APC
A*02:01/Human gp100 (ITDQVPFSV) MHC Tetramer (MHC-LC102)
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- Class: Class I
- Target: gp100
- Specificity: Human
- Peptide: ITDQVPFSV
- Conjugate: PE
A*02:01/Human gp100 (mutant) (IMDQVPFSV) MHC Tetramer (MHC-LC101)
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- Class: Class I
- Target: gp100 (mutant)
- Specificity: Human
- Peptide: IMDQVPFSV
- Conjugate: APC
APC-A*02:01/Human PMEL (YLEPAPVTA) MHC Tetramer (MHC-LC933)
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- Class: Class I
- Target: gp100
- Specificity: Human
- Peptide: YLEPAPVTA
- Conjugate: APC
APC-A*02:01/Human PMEL (YLAPGPVTA) MHC Tetramer (MHC-LC930)
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- Class: Class I
- Target: gp100
- Specificity: Human
- Peptide: YLAPGPVTA
- Conjugate: APC
PE-DRB*01:01/Human PMEL (WNRQLYPEWTEAQRLD) MHC Tetramer (MHC-LC1802)
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- Class: Class II
- Target: gp100
- Specificity: Human
- Peptide: WNRQLYPEWTEAQRLD
- Conjugate: PE
A*02:01/Human gp100 (KTWGQYWQV) MHC Tetramer (MHC-LC014)
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- Class: Class I
- Target: gp100
- Specificity: Human
- Peptide: KTWGQYWQV
- Conjugate: BV421
A*02:01/Human gp100 (Wild) (ITDQVPFSV) MHC Tetramer (MHC-LC003)
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- Class: Class I
- Target: gp100 (Wild)
- Specificity: Human
- Peptide: ITDQVPFSV
- Conjugate: BV421
A*02:01/Human gp100 (mutant) (IMDQVPFSV) MHC Tetramer (MHC-LC002)
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- Class: Class I
- Target: gp100 (mutant)
- Specificity: Human
- Peptide: IMDQVPFSV
- Conjugate: BV421
A*02:01/Human gp100 (mutant) (IMDQVPFSV) MHC Tetramer (MHC-LC100)
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- Class: Class I
- Target: gp100 (mutant)
- Specificity: Human
- Peptide: IMDQVPFSV
- Conjugate: PE
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