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    Human Anti-α5β1 Recombinant Antibody (clone MOR04974) (CAT#: HPAB-0420-YJ)

    This product is a recombinant human antibody that recognizes human Integrin α5β1.

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    • Conjugation:

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    • Purity:

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    • Isotype Switching:

    • Fc Engineering:

    • Modalities:

    Custom Production

    We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.

    Sequences:
    Isotype :
    Purity :
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    Other Requirements:
    We require custom production
    • Published Data
    • Datasheet
    • MSDS
    • COA
    Block

    Figure 1 Anti α5β1-function blocking antibodies induce apoptosis in endothelial cells.

    Figure 1 Anti α5β1-function blocking antibodies induce apoptosis in endothelial cells.

    Inhib

    Figure 2 Inhibition of adhesion of HUVEC cells to fibronectin by α5β1 function blocking IgG antibodies.

    Figure 2 Inhibition of adhesion of HUVEC cells to fibronectin by α5β1 function blocking IgG antibodies.

    FuncS

    Figure 3 HUVEC Caspase assay of anti-α5β1 integrin IgGs.

    Figure 3 HUVEC Caspase assay of anti-α5β1 integrin IgGs.

    FC

    Figure 4 Binding specificity of the anti-α5β1 integrin IgG (example MOR04974) to HT29-wt and HT29α5.

    Figure 4 Binding specificity of the anti-α5β1 integrin IgG (example MOR04974) to HT29-wt and HT29α5.


    Specifications

    • Host Species
    • Human
    • Derivation
    • Phage display library
    • Type
    • Human IgG
    • Specificity
    • Human α5β1
    • Species Reactivity
    • Human
    • Clone
    • MOR04974
    • Applications
    • ELISA, IP, FC, IHC, Block
    • Related Disease
    • Tumor

    Product Property

    • Purity
    • >95% as determined by SDS-PAGE and HPLC analysis
    • Concentration
    • Please refer to the vial label for the specific concentration.
    • Buffer
    • PBS
    • Preservative
    • No preservatives
    • Storage
    • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

    Applications

    • Application Notes
    • This antibody has been reported for use in Enzyme-linked Immunosorbent Assay, Immunoprecipitation, Flow Cytometry, Immunohistochemistry, Blocking.

    Target

    • Alternative Names
    • ITGA5/ITGB1; α5β1; α5β1 Integrin

    Product Notes

    This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

    • Increased sensitivity
    • Confirmed specificity
    • High repeatability
    • Excellent batch-to-batch consistency
    • Sustainable supply
    • Animal-free production

    See more details about Hi-Affi™ recombinant antibody benefits.

    Downloads

    Download resources about recombinant antibody development and antibody engineering to boost your research.

    See other products for "Clone MOR04974"

    See other products for "α5β1"

    Select a product category from the dropdown menu below to view related products.
    Please select product type
    IgG Antibody Products Fab Antibody Products ScFv Antibody Products
    CAT Product Name Application Type
    MHH-1059 Recombinant Human Anti-α5β1 Antibody ELISA, IF, FuncS IgG
    HPAB-0023-YJ Human Anti-α5β1 Recombinant Antibody (HPAB-0023-YJ) FuncS Chimeric (mouse/human) IgG
    HPAB-0049-YJ Mouse Anti-α5β1 Recombinant Antibody (clone B9) ELISA, Neut, IHC, FC, Inhib Mouse IgG1, κ
    HPAB-0421-YJ Human Anti-α5β1 Recombinant Antibody (clone MOR04977) ELISA, IP, FC, IHC, Block Human IgG
    HPAB-2115-FY Human Anti-α5β1 Recombinant Antibody (clone 2H12) Inhib, ELISA Human IgG4

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