Rabbit Anti-ACVR2A Recombinant Antibody (VS13-YC21)
CAT#: VS13-YC21
The Rabbit Anti-ACVR2A Recombinant Antibody is specific for human, mouse and rat ACVR2A. ACVR2A encodes a receptor mediating activin functions, part of the TGF-beta superfamily, involved in processes like ligand-binding. It's linked to preeclampsia susceptibility, with multiple transcript variants due to alternative splicing. The anti-ACVR2A antibody can be used for Western blot (1/500-1/1000).
Gene Expression
Subcellular Location and Protein Expression
Figure 1 IF staining of cell line RH-30
Immunofluorescent staining of cell line RH-30 shows localization to cytosol.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/46997/1150_C7_5_blue_red_green.jpg
Subcellular Location and Protein Expression
Figure 2 IF staining of cell line RT4
Immunofluorescent staining of cell line RT4 shows localization to cytosol.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/46997/1421_G1_4_blue_red_green.jpg
Subcellular Location and Protein Expression
Figure 3 IHC staining of human rectum
Immunohistochemical staining of human rectum shows strong cytoplasmic and membranous positivity in glandular cells.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/46997/ihc_selected.jpg
Normal Tissue
Figure 4 Cerebral cortex
Endothelial cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous Neuronal cells
Staining:High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous nuclear
Neuropil
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/46997/106208_B_7_5.jpg
Normal Tissue
Figure 5 Colon
Endothelial cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/
membranous
Glandular cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Peripheral nerve/ganglion
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/46997/106208_A_9_3.jpg
Normal Tissue
Figure 6 Liver
Hepatocytes
Staining:High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/46997/106208_A_7_4.jpg
Normal Tissue
Figure 7 Kidney
Cells in glomeruli
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
Cells in tubules
Staining:High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/46997/106208_A_8_5.jpg
Normal Tissue
Figure 8 Testis
Cells in seminiferous ducts
Staining:High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
Leydig cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/46997/106208_A_4_6.jpg
Normal Tissue
Figure 9 Lymph node
Germinal center cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/46997/106208_A_9_8.jpg
❮
❯
Specifications
- Immunogen
- Recombinant human ACVR2A.
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human, Mouse and Rat ACVR2A
- Species Reactivity
- Human, Mouse, Rat
- Applications
- WB
- Conjugate
- NONE
Product Property
- Clonality
- Monoclonal
- Purification
- Affinity Chromatography purified
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- 10 mM PBS (pH 7.4) containing 150 mM NaCl, 50% Glycerol and 0.05% BSA.
- Preservative
- 0.02% Sodium azide
- Storage
- Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Shipping with ice pack.
Applications
- Application Notes
- Western blot (WB): 1/500-1/1000
Target
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Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Secondary Antibody
- CAT
- Product Name
Isotype Control
- CAT
- Product Name
See other products for "ACVR2A"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0361CL | Anti-Human ACVR2A Recombinant Antibody (APE2990) | ELISA, FuncS, Inhib | |
| TAB-0361CL-S(P) | Anti-Human ACVR2A Recombinant Antibody scFv Fragment (APE2990) | ELISA, FuncS, Inhib | |
| TAB-0362CL-S(P) | Anti-Human ACVR2A Recombinant Antibody scFv Fragment (APE2991) | ELISA, FuncS, Inhib | |
| TAB-0363CL-S(P) | Anti-Human ACVR2A Recombinant Antibody scFv Fragment (APE2665) | ELISA, FuncS, Inhib | |
| TAB-0364CL-S(P) | Anti-Human ACVR2A Recombinant Antibody scFv Fragment (APE2666) | ELISA, FuncS, Inhib |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0653CLV | Mouse Anti-ACVR2A Recombinant Antibody (TAB-0653CLV) | ELISA | Mouse IgG |
| TAB-0653CLV-F(E) | Mouse Anti-ACVR2A Recombinant Antibody; Fab Fragment (TAB-0653CLV-F(E)) | ELISA | Mouse Fab |
| TAB-0653CLV-S(P) | Mouse Anti-ACVR2A Recombinant Antibody; scFv Fragment (TAB-0653CLV-S(P)) | ELISA | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-0427MZ | Mouse Anti-ACVR2A Recombinant Antibody (clone 250/2) | IP, WB | Mouse IgG1 |
| HPAB-0134-FY | Mouse Anti-ACVR2A Recombinant Antibody (HPAB-0134-FY) | ELISA, Neut | Mouse IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-0063 | Hi-Affi™ Rabbit Anti-ACVR2A Recombinant Antibody (clone DS63AB) | WB | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0134-FY-S(P) | Mouse Anti-ACVR2A Recombinant Antibody; scFv Fragment (HPAB-0134-FY-S(P)) | ELISA | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0134-FY-F(E) | Mouse Anti-ACVR2A Recombinant Antibody; Fab Fragment (HPAB-0134-FY-F(E)) | ELISA | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC626 | Recombinant Anti-ACVR2A Vesicular Antibody, EV Displayed (VS-0425-YC626) | ELISA, FC, Neut, Cell-uptake |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY137 | Anti-ACVR2A Immunohistochemistry Kit | IHC | |
| VS-0525-XY138 | Anti-Human ACVR2A Immunohistochemistry Kit | IHC | |
| VS-0525-XY139 | Anti-Mouse ACVR2A Immunohistochemistry Kit | IHC |
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