Mouse Anti-ALPP Recombinant Antibody (clone H17E2); scFv Fragment (CAT#: HPAB-0014-YJ-S(P))
This product is a recombinant mouse scFv that recognizes human placental alkaline phosphatase (PLAP). Mab H17E2 is used to evaluate placental-like alkaline phosphatase (PLAP) as a serum marker of testicular germ cell tumours and functions in the treatment or diagnosis of cancer.
Specific Inquiry
Subcellular Location and Protein Expression
Normal Tissue
Figure 1 IF staining of human cell line HeLa
(Immunofluorescent staining of human cell line HeLa shows localization to plasma membrane.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/38764/1046_F10_4_selected.jpg
(Immunofluorescent staining of human cell line HeLa shows localization to plasma membrane.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/38764/1046_F10_4_selected.jpg
Figure 2 IHC staining of human placenta
(Immunohistochemical staining of human placenta shows strong membranous and cytoplasmic positivity in trophoblastic cells.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/38765/98876_A_1_7_selected.jpg
(Immunohistochemical staining of human placenta shows strong membranous and cytoplasmic positivity in trophoblastic cells.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/38765/98876_A_1_7_selected.jpg
Figure 3 Placenta
(Trophoblastic cells
Staining:High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/38764/98884_A_1_7.jpg
(Trophoblastic cells
Staining:High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/38764/98884_A_1_7.jpg
Specifications
- Host Species
- Mouse
- Type
- Mouse scFv
- Specificity
- Human ALPP
- Species Reactivity
- Human
- Clone
- H17E2
- Applications
- IHC, ELISA
- Related Disease
- Cancer
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- Alkaline Phosphatase, Placental; Alkaline Phosphatase Regan Isozyme; Placental Alkaline Phosphatase 1; EC 3.1.3.1; PLAP-1; PLAP; Alkaline Phosphatase, Placental (Regan Isozyme); H17E2; H17EZ
- Gene ID
- 250
- UniProt ID
- P05187
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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Single Domain Antibody Products
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Fab Antibody Products
ScFv Antibody Products
IgG Antibody Products
Antibody Magnetic Beads
ScFv-Fc Chimera Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NAB-146-sdAb | Recombinant Anti-Human ALPP VHH Single Domain Antibody | FUNC, FA, IP, ChiP | Llama VHH |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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