Human Anti-BTLA Recombinant Antibody (clone Icatolimab) (CAT#: VS-0723-WK43)
This product is a chimeric (mouse/human) IgG4 antibody that recognizes human BTLA, which is a receptor that relays inhibitory signals to suppress the immune response. Icatolimab is recommended for flow cytometry (1/100) and ELISA (1/5000-1/10000) assays.
Specific Inquiry
Normal Tissue
RNA Expression
Figure 1 IHC staining of human spleen
(Immunohistochemical staining of human spleen shows strong cytoplasmic positivity in a subset of cells in red pulp.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/47211/ihc_selected.jpg
(Immunohistochemical staining of human spleen shows strong cytoplasmic positivity in a subset of cells in red pulp.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/47211/ihc_selected.jpg
Figure 2 Tonsil
(High expression)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/62029/ihc_selected.jpg
(High expression)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/62029/ihc_selected.jpg
Figure 3 Lymph node
(Germinal center cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/62029/148776_A_8_8.jpg
(Germinal center cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/62029/148776_A_8_8.jpg
Figure 4 RNA cell line category: Cell line enhanced (U-698)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000186265-BTLA
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000186265-BTLA
Specifications
- Immunogen
- Recombinant human BTLA protein
- Host Species
- Human
- Derivation
- Chimeric (mouse/human)
- Type
- Chimeric (mouse/human) IgG4
- Specificity
- Human BTLA
- Species Reactivity
- Human
- Clone
- Icatolimab
- Applications
- ELISA, FC
- Conjugate
- Unconjugated
Product Property
- Clonality
- Monoclonal
- Purification
- Protein A purified
- Purity
- >95%
- Format
- Lyophilized
- Buffer
- Lyophilized from sterile PBS (pH 7.4) with 5%-8% trehalose.
- Preservative
- No Preservative
- Storage
- Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
- Shipping
- Ice packs
Applications
- Application Notes
- ELISA: 1/5000-1/10000
Flow Cytometry: 1/100
Target
Recommended Products
Isotype Control
Secondary Antibody
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "BTLA"
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Please select product type
Human Antibody
Blocking Antibody
Neutralizing Antibody
scFv Fragment Antibody
Fab Fragment Antibody
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-1309CL | Human Anti-BTLA Recombinant Antibody (TAB-1309CL) | Inhib | Human IgG |
| TAB-1310CL | Human Anti-BTLA Recombinant Antibody (TAB-1310CL) | Block | Human IgG |
| TAB-1309CL-S(P) | Human Anti-BTLA Recombinant Antibody; scFv Fragment (TAB-1309CL-S(P)) | ELISA | Human scFv |
| TAB-1310CL-S(P) | Human Anti-BTLA Recombinant Antibody; scFv Fragment (TAB-1310CL-S(P)) | ELISA | Human scFv |
| TAB-1311CL-S(P) | Human Anti-BTLA Recombinant Antibody; scFv Fragment (TAB-1311CL-S(P)) | ELISA | Human scFv |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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