Human Anti-BTLA Recombinant Antibody (clone Icatolimab)
CAT#: VS-0723-WK43
This product is a chimeric (mouse/human) IgG4 antibody that recognizes human BTLA, which is a receptor that relays inhibitory signals to suppress the immune response. Icatolimab is recommended for flow cytometry (1/100) and ELISA (1/5000-1/10000) assays.
Gene Expression
Normal Tissue
Figure 1 IHC staining of human spleen
Immunohistochemical staining of human spleen shows strong cytoplasmic positivity in a subset of cells in red pulp.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/47211/ihc_selected.jpg
Normal Tissue
Figure 2 Tonsil
High expression
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/62029/ihc_selected.jpg
Normal Tissue
Figure 3 Lymph node
Germinal center cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/62029/148776_A_8_8.jpg
RNA Expression
Figure 4 RNA cell line category: Cell line enhanced (U-698)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000186265-BTLA
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Specifications
- Immunogen
- Recombinant human BTLA protein
- Host Species
- Human
- Derivation
- Chimeric (mouse/human)
- Type
- Chimeric (mouse/human) IgG4
- Specificity
- Human BTLA
- Species Reactivity
- Human
- Clone
- Icatolimab
- Applications
- ELISA, FC
- Conjugate
- Unconjugated
Product Property
- Clonality
- Monoclonal
- Purification
- Protein A purified
- Purity
- >95%
- Format
- Lyophilized
- Buffer
- Lyophilized from sterile PBS (pH 7.4) with 5%-8% trehalose.
- Preservative
- No Preservative
- Storage
- Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
- Shipping
- Ice packs
Applications
- Application Notes
- ELISA: 1/5000-1/10000
Flow Cytometry: 1/100
Target
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Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Isotype Control
- CAT
- Product Name
Secondary Antibody
- CAT
- Product Name
See other products for "Clone icatolimab"
- CAT
- Product Name
See other products for "BTLA"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-1309CL | Human Anti-BTLA Recombinant Antibody (TAB-1309CL) | Inhib | Human IgG |
| TAB-1310CL | Human Anti-BTLA Recombinant Antibody (TAB-1310CL) | Block | Human IgG |
| TAB-1311CL | Human Anti-BTLA Recombinant Antibody (TAB-1311CL) | ELISA | Human IgG1 |
| TAB-1309CL-S(P) | Human Anti-BTLA Recombinant Antibody; scFv Fragment (TAB-1309CL-S(P)) | ELISA | Human scFv |
| TAB-1310CL-S(P) | Human Anti-BTLA Recombinant Antibody; scFv Fragment (TAB-1310CL-S(P)) | ELISA | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-074CQ | Mouse Anti-BTLA Recombinant Antibody (clone PJ196) | Block, FC | Mouse IgG1 |
| NEUT-075CQ | Hamster Anti-BTLA Recombinant Antibody (clone 6A6) | FC, IP, Block | Hamster IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-076CQ | Mouse Anti-BTLA Recombinant Antibody (clone 6F7) | FC, FuncS, Neut | Mouse IgG1, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-1605LY-S(P) | Human Anti-BTLA Recombinant Antibody; scFv Fragment (HPAB-1605LY-S(P)) | ELISA, FC | Humanized scfv |
| HPAB-M0448-YC-S(P) | Mouse Anti-BTLA Recombinant Antibody; scFv Fragment (HPAB-M0448-YC-S(P)) | FC | Mouse scFv |
| HPAB-0194-WJ-S(P) | Mouse Anti-BTLA Recombinant Antibody; scFv Fragment (HPAB-0194-WJ-S(P)) | ELISA, FC, WB, Neut | Mouse scFv |
| HPAB-0195-WJ-S(P) | Mouse Anti-BTLA Recombinant Antibody; scFv Fragment (HPAB-0195-WJ-S(P)) | ELISA, FC, WB, Neut | Mouse scFv |
| HPAB-0196-WJ-S(P) | Mouse Anti-BTLA Recombinant Antibody; scFv Fragment (HPAB-0196-WJ-S(P)) | ELISA, FC, WB, Neut | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-1605LY | Human Anti-BTLA Recombinant Antibody (HPAB-1605LY) | ELISA, FC | Humanized IgG |
| FN-025CQ | Rat Anti-BTLA Recombinant Antibody (FN-025CQ) | FC, ELISA, FuncS | Rat IgG1 |
| FN-035CQ | Mouse Anti-BTLA Recombinant Antibody (clone ANC6E9) | ELISA, FC, FuncS | Mouse IgG1, κ |
| FN-079CQ | Mouse Anti-BTLA Recombinant Antibody (clone 8F4) | FC | Mouse IgG1, κ |
| FAMAB-1593CQ | Mouse Anti-BTLA Recombinant Antibody (clone HMBT-6B2) | Block, FuncS, IB, IP, WB, FC | Mouse IgG2a |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-1605LY-F(E) | Human Anti-BTLA Recombinant Antibody; Fab Fragment (HPAB-1605LY-F(E)) | ELISA, FC | Humanized Fab |
| HPAB-M0448-YC-F(E) | Mouse Anti-BTLA Recombinant Antibody; Fab Fragment (HPAB-M0448-YC-F(E)) | FC | Mouse Fab |
| HPAB-0194-WJ-F(E) | Mouse Anti-BTLA Recombinant Antibody; Fab Fragment (HPAB-0194-WJ-F(E)) | ELISA, FC, WB, Neut | Mouse Fab |
| HPAB-0195-WJ-F(E) | Mouse Anti-BTLA Recombinant Antibody; Fab Fragment (HPAB-0195-WJ-F(E)) | ELISA, FC, WB, Neut | Mouse Fab |
| HPAB-0196-WJ-F(E) | Mouse Anti-BTLA Recombinant Antibody; Fab Fragment (HPAB-0196-WJ-F(E)) | ELISA, FC, WB, Neut | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0225-XY6 | CytoStream™ Mouse Anti-BTLA Recombinant Antibody (VS-0225-XY6) | FC | Mouse IgG1, kappa |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-FY62 | Human Anti-BTLA (clone icatolimab) scFv-Fc Chimera | ELISA, FC | Human IgG4, scFv-Fc |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC609 | Recombinant Anti-BTLA Vesicular Antibody, EV Displayed (VS-0425-YC609) | ELISA, FC, SPR, Neut, Cell-uptake |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY855 | Anti-BTLA Immunohistochemistry Kit | IHC |
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