Rabbit Anti-CCR8 Recombinant Antibody (clone R07-8E8) (CAT#: VS3-XY3291)
This is a recombinant rabbit antibody that specifically recognizes human CCR8 (C-C motif chemokine receptor 8), which regulates monocyte chemotaxis and thymic cell line apoptosis. It also has cross-reactivity against mouse or rat CCR8. It has been reported for use in Western Blot, Immunocytochemistry or Immunofluorescence. The recommended dilutions of Western Blot and Immunofluorescence is 1/500-1/1000 and 1/50-1/200, respectively.
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Normal Tissue
RNA Expression
Figure 1 Low expression in fallopian tube
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/42383/162877_A_7_7_val_selected.jpg
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/42383/162877_A_7_7_val_selected.jpg
Figure 2 Colon
(Glandular cells Staining: Not detected Intensity: Weak Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/42383/162877_A_7_3.jpg
(Glandular cells Staining: Not detected Intensity: Weak Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/42383/162877_A_7_3.jpg
Figure 3 Kidney
(Cells in tubules Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous nuclear)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/42383/162877_A_9_5.jpg
(Cells in tubules Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous nuclear)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/42383/162877_A_9_5.jpg
Figure 4 Testis
(Cells in seminiferous ducts Staining: Not detected Intensity: Weak Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/42383/162877_A_6_6.jpg
(Cells in seminiferous ducts Staining: Not detected Intensity: Weak Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/42383/162877_A_6_6.jpg
Figure 5 RNA cell line category: Cell line enriched (HDLM-2)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000179934-CCR8
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000179934-CCR8
Specifications
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human, Mouse and Rat CCR8
- Species Reactivity
- Human, Mouse, Rat
- Clone
- R07-8E8
- Applications
- WB, ICC, IF
- Related Disease
- Molluscum Contagiosum; Kaposi Sarcoma
Product Property
- Clonality
- Monoclonal
- Aggregation
- < 5%
- Format
- Liquid
- Buffer
- PBS (pH 7.4), 150 mM NaCl and 50% glycerol
- Preservative
- 0.02% sodium azide
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
- Shipping
- Ice packs
Applications
- Application Notes
- WB: 1/500-1/1000
IF: 1/50-1/200
Target
- Alternative Names
- CY6; TER1; CCR-8; CKRL1; CDw198; CMKBR8; GPRCY6; CMKBRL2; CC-CKR-8
- Gene ID
- 1237
- UniProt ID
- P51685
- Long Name
- C-C motif chemokine receptor 8
- Cellular Localization
- Cell membrane
- Post Translation Modifications
- Modification sites at PhosphoSitePlus (P51685)
Modification sites at neXtProt (NX_P51685)
- Protein Refseq
- NP_005192.1
- Function
- Receptor for the chemokine CCL1/SCYA1/I-309. May regulate monocyte chemotaxis and thymic cell line apoptosis. Alternative coreceptor with CD4 for HIV-1 infection.
Recommended Products
Isotype Control
Recommended Dilution Buffer
Secondary Antibody
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-3049z-F(E) | Recombinant Anti-Human CCR8 Antibody Fab Fragment | RIA, IF, FuncS | Fab |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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