Rabbit Anti-CCR8 Recombinant Antibody (clone R07-8E8)
CAT#: VS3-XY3291
This is a recombinant rabbit antibody that specifically recognizes human CCR8 (C-C motif chemokine receptor 8), which regulates monocyte chemotaxis and thymic cell line apoptosis. It also has cross-reactivity against mouse or rat CCR8. It has been reported for use in Western Blot, Immunocytochemistry or Immunofluorescence. The recommended dilutions of Western Blot and Immunofluorescence is 1/500-1/1000 and 1/50-1/200, respectively.
Gene Expression
Normal Tissue
Figure 1 Low expression in fallopian tube
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/42383/162877_A_7_7_val_selected.jpg
Normal Tissue
Figure 2 Colon
Glandular cells Staining: Not detected Intensity: Weak Quantity: <25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/42383/162877_A_7_3.jpg
Normal Tissue
Figure 3 Kidney
Cells in tubules Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous nuclear
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/42383/162877_A_9_5.jpg
Normal Tissue
Figure 4 Testis
Cells in seminiferous ducts Staining: Not detected Intensity: Weak Quantity: <25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/42383/162877_A_6_6.jpg
RNA Expression
Figure 5 RNA cell line category: Cell line enriched (HDLM-2)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000179934-CCR8
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Specifications
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human, Mouse and Rat CCR8
- Species Reactivity
- Human, Mouse, Rat
- Clone
- R07-8E8
- Applications
- WB, ICC, IF
- Related Disease
- Molluscum Contagiosum; Kaposi Sarcoma
Product Property
- Clonality
- Monoclonal
- Aggregation
- < 5%
- Format
- Liquid
- Buffer
- PBS (pH 7.4), 150 mM NaCl and 50% glycerol
- Preservative
- 0.02% sodium azide
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
- Shipping
- Ice packs
Applications
- Application Notes
- WB: 1/500-1/1000
IF: 1/50-1/200
Target
- Alternative Names
- CY6; TER1; CCR-8; CKRL1; CDw198; CMKBR8; GPRCY6; CMKBRL2; CC-CKR-8
- Gene ID
- 1237
- UniProt ID
- P51685
- Long Name
- C-C motif chemokine receptor 8
- Cellular Localization
- Cell membrane
- Post Translation Modifications
- Modification sites at PhosphoSitePlus (P51685)
Modification sites at neXtProt (NX_P51685)
- Protein Refseq
- NP_005192.1
- Function
- Receptor for the chemokine CCL1/SCYA1/I-309. May regulate monocyte chemotaxis and thymic cell line apoptosis. Alternative coreceptor with CD4 for HIV-1 infection.
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
Isotype Control
- CAT
- Product Name
Recommended Dilution Buffer
- CAT
- Product Name
Secondary Antibody
- CAT
- Product Name
See other products for "CCR8"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-3049z | Mouse Anti-CCR8 Recombinant Antibody (MOB-3049z) | FC | Mouse IgG1, κ |
| VS4-WK73 | Human Anti-CCR8 Recombinant Antibody (clone 6B12) | FC | Human IgG1 |
| VS4-WK74 | Human Anti-CCR8 Recombinant Antibody (clone 2C10) | FC | Human IgG1 |
| VS4-WK75 | Human Anti-CCR8 Recombinant Antibody (clone 10A9) | FC | Human IgG1, Lambda |
| VS-0723-WK224 | Rabbit Anti-CCR8 Recombinant Antibody (VS-0723-WK224) | ELISA, FC | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-3049z-F(E) | Recombinant Anti-Human CCR8 Antibody Fab Fragment | RIA, IF, FuncS | Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-3049z-S(P) | Recombinant Anti-Human CCR8 Antibody scFv Fragment | ELISA, IP, FuncS | scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-274CQ | Rat Anti-CCR8 Recombinant Antibody (clone CBL712) | Neut | Rat IgG2b |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-0524 | Hi-Affi™ Rabbit Anti-CCR8 Recombinant Antibody (clone DS524AB) | WB, ICC | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC46 | Recombinant Anti-CCR8 Vesicular Antibody, EV Displayed (VS-0425-YC46) | ELISA, FC, Cell-uptake |
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