Human Anti-CD52 Recombinant Antibody Hexamer (VS-0924-YC121), CDC Enhanced (CAT#: VS-0924-YC121)
This product is a human anti-CD52 antibody hexamer designed for enhanced complement-dependent cytotoxicity (CDC). The hexameric IgG1 specifically targets human CD52 and includes mutations that promote hexamer formation, optimizing C1q binding and enhancing CDC activity.
Specific Inquiry
RNA Expression
Figure 1 RNA cell line category: Group enriched (Daudi, REH, U-266/84, U-698)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000169442-CD52
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000169442-CD52
Figure 1 RNA cell line category: Group enriched (Daudi, REH, U-266/84, U-698)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000169442-CD52
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000169442-CD52
Specifications
- Host Species
- Human
- Derivation
- Humanized
- Type
- Antibody hexamer
- Specificity
- Human CD52
- Species Reactivity
- Human
- Molecule Class
- ~ 900 kDa
- Applications
- ELISA, FC, CDC
- Conjugate
- None
- Related Disease
- Autoimmune diseases, cancer, graft rejection
Product Property
- Clonality
- Monoclonal
- Purification
- Protein A purified
- Purity
- >95% determined as SDS-PAGE and SEC-HPLC
- Aggregation
- <5%
- Buffer
- PBS, pH 7.4
- Preservative
- No preservatives
- Storage
- Store at 4°C short term (1-2 weeks). Store at -20°C long term (12 months). Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- CD52; Epididymis Secretory Sperm Binding Protein Li 171mP; CAMPATH-1 Antigen; CD52 Antigen (CAMPATH-1 Antigen); Cambridge Pathology 1 Antigen; Epididymal Secretory Protein E5; He5; HEL-S-171mP
- Gene ID
- 1043
- UniProt ID
- P31358
- Long Name
- CD52 Molecule
- Cellular Localization
- Cell membrane; Lipid-anchor, GPI-anchor
- Post Translation Modifications
- Glycosylation at Asn27 and Asn40
- Function
- May play a role in carrying and orienting carbohydrate, as well as having a more specific role.
Downloads
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Extracellular Vesicle (EV) Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PFBC-021 | Rat Anti-CD52 Recombinant Antibody (clone CAMPATH-1G); Fab Fragment | WB, IHC, IF, FuncS | Rat IgG2b |
| FAMAB-0045-YC-F(E) | Rat Anti-CD52 Recombinant Antibody (clone YTH 34.5HL); Fab Fragment | ELISA | Rat Fab |
| HPAB-0748-FY-S(P) | Mouse Anti-CD52 Recombinant Antibody (clone HI52); Fab Fragment | Inhib | Mouse Fab |
| HPAB-0398-YJ-F(E) | Human Anti-CD52 Recombinant Antibody; Fab Fragment (HPAB-0398-YJ-F(E)) | ELISA, Inhib, Immunocontraception | Human Fab |
| HPAB-0387-FY-F(E) | Human Anti-CD52 Recombinant Antibody; Fab Fragment (HPAB-0387-FY-F(E)) | WB | Humanized Fab |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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