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    Human Anti-CD52 Recombinant Antibody Hexamer (VS-0924-YC121), CDC Enhanced

    CAT#: VS-0924-YC121

    This product is a human anti-CD52 antibody hexamer designed for enhanced complement-dependent cytotoxicity (CDC). The hexameric IgG1 specifically targets human CD52 and includes mutations that promote hexamer formation, optimizing C1q binding and enhancing CDC activity.

    Gene Expression
    ❮
    Figure 1 RNA cell line category: Group enriched (Daudi, REH, U-266/84, U-698)
    ❯

    Specifications

    • Host Species
    • Human
    • Derivation
    • Humanized
    • Type
    • Antibody hexamer
    • Specificity
    • Human CD52
    • Species Reactivity
    • Human
    • Molecule Class
    • ~ 900 kDa
    • Applications
    • ELISA, FC, CDC
    • Conjugate
    • None
    • Related Disease
    • Autoimmune diseases, cancer, graft rejection

    Product Property

    • Clonality
    • Monoclonal
    • Purification
    • Protein A purified
    • Purity
    • >95% determined as SDS-PAGE and SEC-HPLC
    • Aggregation
    • <5%
    • Buffer
    • PBS, pH 7.4
    • Preservative
    • No preservatives
    • Storage
    • Store at 4°C short term (1-2 weeks). Store at -20°C long term (12 months). Avoid repeated freeze/thaw cycles.

    Target

    • Alternative Names
    • CD52; Epididymis Secretory Sperm Binding Protein Li 171mP; CAMPATH-1 Antigen; CD52 Antigen (CAMPATH-1 Antigen); Cambridge Pathology 1 Antigen; Epididymal Secretory Protein E5; He5; HEL-S-171mP
    • Long Name
    • CD52 Molecule
    • Cellular Localization
    • Cell membrane; Lipid-anchor, GPI-anchor
    • Post Translation Modifications
    • Glycosylation at Asn27 and Asn40
    • Function
    • May play a role in carrying and orienting carbohydrate, as well as having a more specific role.
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    Datasheet

    Datasheet - VS-0924-YC121.pdf

    MSDS

    MSDS - VS-0924-YC121.pdf

    COA

    Certificate of Analysis Lookup

    To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.

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