Human Anti-CD52 Recombinant Antibody Hexamer (VS-0924-YC121), CDC Enhanced
CAT#: VS-0924-YC121
This product is a human anti-CD52 antibody hexamer designed for enhanced complement-dependent cytotoxicity (CDC). The hexameric IgG1 specifically targets human CD52 and includes mutations that promote hexamer formation, optimizing C1q binding and enhancing CDC activity.
Gene Expression
RNA Expression
Figure 1 RNA cell line category: Group enriched (Daudi, REH, U-266/84, U-698)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000169442-CD52
❮
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Specifications
- Host Species
- Human
- Derivation
- Humanized
- Type
- Antibody hexamer
- Specificity
- Human CD52
- Species Reactivity
- Human
- Molecule Class
- ~ 900 kDa
- Applications
- ELISA, FC, CDC
- Conjugate
- None
- Related Disease
- Autoimmune diseases, cancer, graft rejection
Product Property
- Clonality
- Monoclonal
- Purification
- Protein A purified
- Purity
- >95% determined as SDS-PAGE and SEC-HPLC
- Aggregation
- <5%
- Buffer
- PBS, pH 7.4
- Preservative
- No preservatives
- Storage
- Store at 4°C short term (1-2 weeks). Store at -20°C long term (12 months). Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- CD52; Epididymis Secretory Sperm Binding Protein Li 171mP; CAMPATH-1 Antigen; CD52 Antigen (CAMPATH-1 Antigen); Cambridge Pathology 1 Antigen; Epididymal Secretory Protein E5; He5; HEL-S-171mP
- Gene ID
- 1043
- UniProt ID
- P31358
- Long Name
- CD52 Molecule
- Cellular Localization
- Cell membrane; Lipid-anchor, GPI-anchor
- Post Translation Modifications
- Glycosylation at Asn27 and Asn40
- Function
- May play a role in carrying and orienting carbohydrate, as well as having a more specific role.
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Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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