Anti-Human CD52 Recombinant Antibody (CF1D12) (CAT#: TAB-312LC)
This product is a recombinant mouse antibody that recognizes CD52. It exhibits a dose-dependent effect in enhancing T cell responses to antigens in PBMCs. The antibody enhances T cell responses to antigens in people at risk for type 1 diabetes.
Specific Inquiry
FuncS
Figure 1 CF1D12 enhances responses of T cells in PBMCs to antigens.
IFN-γ spots per ELISpot plate well for PBMCs pre-incubated with either an isotype control antibody or CF1D12 for 1 h at 37°C and subsequently exposed to no antigen, TT or GAD65 in the presence (black bars) or absence (white bars, labelled 'Antibody pre-bound only') of additional antibody.
FuncS
Figure 2 CF1D12 exhibits a dose-dependent effect in enhancing responses of T cells in PBMCs to antigens.
IFN-γ spots per ELISpot plate well for PBMCs pre-incubated with CF1D12 for 1 h at 37°C and subsequently exposed to TT in the presence (black bars) or absence (white bars, labelled 'Antibody pre-bound') of additional CF 1 D 12 antibody.
FuncS
Figure 3 CF1D12 enhances T cell response to antigens in people at risk for type 1 diabetes.
IFN-γ spots per ELISpot plate well for PBMCs incubated with isotype control antibody or CF 1 D 12 in the presence of no antigen, TT or GAD65.
Specifications
- Host Species
- Mouse
- Specificity
- Human
- Clone
- CF1D12
- Applications
- FuncS
- Related Disease
- Autoimmune disease
Applications
- Application Notes
- This antibody has been reported for use in Functional Assay.
Target
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| PFBC-021 | Rat Anti-CD52 Recombinant Antibody (clone CAMPATH-1G); Fab Fragment | WB, IHC, IF, FuncS | Rat IgG2b |
| FAMAB-0045-YC-F(E) | Rat Anti-CD52 Recombinant Antibody (clone YTH 34.5HL); Fab Fragment | ELISA | Rat Fab |
| HPAB-0748-FY-S(P) | Mouse Anti-CD52 Recombinant Antibody (clone HI52); Fab Fragment | Inhib | Mouse Fab |
| HPAB-1835-FY-S(P) | Human Anti-CD52 Recombinant Antibody (clone 4D9); Fab Fragment | ELISA | Human Fab |
| HPAB-1836-FY-S(P) | Human Anti-CD52 Recombinant Antibody (clone 5E3); Fab Fragment | ELISA | Human Fab |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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