Mouse Anti-CD52 Recombinant Antibody Hexamer (VS-0924-YC122), CDC Enhanced (CAT#: VS-0924-YC122)
The product is a hexameric anti-CD52 mouse antibody with enhanced complement-dependent cytotoxicity (CDC) activity. This IgG1 antibody targets human CD52 and has been engineered with hexamerization-enhancing mutations that promote hexamer formation, thereby facilitating optimal C1q binding and boosting CDC efficacy.
Specific Inquiry
RNA Expression
Figure 1 RNA cell line category: Group enriched (Daudi, REH, U-266/84, U-698)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000169442-CD52
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000169442-CD52
Figure 1 RNA cell line category: Group enriched (Daudi, REH, U-266/84, U-698)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000169442-CD52
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000169442-CD52
Specifications
- Host Species
- Mouse
- Type
- Antibody hexamer
- Specificity
- Human CD52
- Species Reactivity
- Human
- Molecule Class
- ~ 900 kDa
- Applications
- Inhib, CDC
- Conjugate
- None
Product Property
- Clonality
- Monoclonal
- Purification
- Protein G purified
- Purity
- >95% determined as SDS-PAGE and SEC-HPLC
- Aggregation
- <5%
- Buffer
- PBS, pH 7.4
- Preservative
- No preservatives
- Storage
- Store at 4°C short term (1-2 weeks). Store at -20°C long term (12 months). Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- CD52 Molecule; Human Epididymis-Specific Protein 5; CD52 Antigen (CAMPATH-1 Antigen); Epididymal Secretory Protein E5; Cambridge Pathology 1 Antigen; CDW52; He5;
- Gene ID
- 1043
- UniProt ID
- P31358
- Long Name
- CD52 Molecule
- Cellular Localization
- Cell membrane; Lipid-anchor, GPI-anchor
- Post Translation Modifications
- Glycosylation at Asn27 and Asn40
- Function
- May play a role in carrying and orienting carbohydrate, as well as having a more specific role.
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Extracellular Vesicle (EV) Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1223z | Mouse Anti-CD52 Recombinant Antibody (clone 20C9) | WB, ELISA, FC, IHC, FuncS | Mouse IgG1, κ |
| HPAB-0748-FY | Mouse Anti-CD52 Recombinant Antibody (clone HI52) | Inhib | Mouse IgG |
| HPAB-0398-YJ | Human Anti-CD52 Recombinant Antibody (HPAB-0398-YJ) | ELISA, Inhib, Immunocontraception | Human IgG1 |
| HPAB-1835-FY | Human Anti-CD52 Recombinant Antibody (clone 4D9) | ELISA | Human IgG |
| HPAB-1836-FY | Human Anti-CD52 Recombinant Antibody (clone 5E3) | ELISA | Human IgG |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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