Mouse Anti-CEA Recombinant Antibody (clone CEA 79) (CAT#: FAMAB-0053CQ)

Recombinant Mouse Antibody clone CEA 79, which is specific to CEA. The monoclonal anti-carcinoembryonic antigen (CEA) antibody cross-reactive with nonspecific cross-reacting antigen-95 (NCA-95).


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IB

Figure 1 Immunoblot analysis of CEA 79 scFv displayed on the phage surface.

Figure 1 Immunoblot analysis of CEA 79 scFv displayed on the phage surface.

The scFv on the surface of the phage recognized both CEA (arrow) and NCA-95 (arrowhead).

Chung, J. H., Choi, S. J., Kim, H. J., Kim, I. J., Choi, I. H., Do Lee, S., ... & Chung, H. K. (1997). Cloning and Characterization of cDNAs Encoding V H and V L of a Monoclonal Anti-CEA Antibody (CEA 79) Cross-reactive with NCA-95 and Generation of a Single-Chain Fv Molecule (scFv). Molecules & Cells (Springer Science & Business Media BV), 7(6).

Figure 2 Anterior abdominal image of a patient with car cinoma in the descending colon. I-131 labeled anti-CEA antibody is shown to be accumulated in the tumor.

Figure 2 Anterior abdominal image of a patient with car cinoma in the descending colon. I-131 labeled anti-CEA antibody is shown to be accumulated in the tumor.

The scan of a patient with cancer of the descending colon. Dense uptake of 1-131 labeled CEA-79 was seen in the tumor mass. There was also some uptake, into the bone marrow and liver.

Chung, J. K., Choi, C. W., Lee, M. C., Chung, H. K., Kim, N. K., Choi, K. W., & Koh, C. S. (1993). Radioimmunoscintigraphy of advanced gastrointestinal carcinomas employing I-131 labeled CEA-79 monoclonal antibody. Annals of nuclear medicine, 7(2), 65-70.


Specifications

  • Host Species
  • Mouse
  • Derivation
  • scFv phage display library
  • Type
  • Mouse IgG2a, κ
  • Specificity
  • Human CEA
  • Species Reactivity
  • Human
  • Clone
  • CEA 79
  • Applications
  • ELISA, WB, IP
  • Related Disease
  • Cancers

Product Property

  • Purity
  • >95% as determined by SDS-PAGE and HPLC analysis
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Applications

  • Application Notes
  • This antibody has been tested for use in Immunoblotting.

Target

  • Alternative Names
  • CEA; Carcinoembryonic Antigen; carcinoma embryonic Antigen

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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