Human Anti-CEA Recombinant Antibody (clone Ch F11-39)

CAT#: FAMAB-0064YC

Carcinoembryonic antigen (CEA), a highly glycosylated glycoprotein with a molecular weight of 180,000, is one of the most useful human tumor markers. Provided is a chimeric (human/mouse) monoclonal antibody against carcinoembryonic antigen (CEA), designated chF11-39. The antibody is able to discriminate CEA in tumor tissues from the CEA-related normal antigens.

Specifications

  • Host Species
  • Human
  • Derivation
  • Chimeric (mouse/human)
  • Type
  • Chimeric (mouse/human) IgG1, κ
  • Specificity
  • Human CEA
  • Species Reactivity
  • Human
  • Clone
  • Ch F11-39
  • Applications
  • IP, FuncS
  • Related Disease
  • Tumor

Product Property

  • Purity
  • >95% as determined by SDS-PAGE and HPLC analysis
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

  • Alternative Names
  • CEA; Carcinoembryonic antigen
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Breast cancer biomarkers at key points during disease progression
Great Tumor Specificity
The ability of the Ch F11-39 clone to discriminate between CEA in tumor tissues and normal CEA-related antigens is remarkable. We used this chimeric mouse/human antibody in functional studies, and the differentiation it provided was superior to other antibodies we have tested. It is a vital tool for our tumor marker research.
Breast cancer biomarkers at key points during disease progression
High Purity Functional Antibody
We required a high-purity antibody for immunoprecipitation, and this product delivered with greater than 95% purity as determined by SDS-PAGE. The chimeric IgG1 format worked well in our setup. The antibody effectively targets the highly glycosylated glycoprotein CEA, providing robust signals in our assays without cross-reactivity issues.

Q&As

  1. Can this antibody distinguish between tumor and normal CEA?

    A: Yes, this antibody (clone Ch F11-39) is capable of discriminating CEA in tumor tissues from CEA-related normal antigens. It is a chimeric (mouse/human) monoclonal antibody designed to target Carcinoembryonic antigen (CEA) with high specificity, making it suitable for research involving tumor markers.

  2. What is the purity level of this recombinant antibody?

    A: We ensure high quality for our products; this Anti-CEA Recombinant Antibody has a purity of greater than 95% as determined by both SDS-PAGE and HPLC analysis. It is a Chimeric IgG1, kappa antibody that has been validated for Immunoprecipitation (IP) and Functional Studies (FuncS).

View the frequently asked questions answered by Creative Biolabs Support.

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Downloadable Resources

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Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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