Rabbit Anti-CLDN4 Recombinant Antibody (clone R06-4F2) (CAT#: VS3-XY3319)

This antibody is a recombinant rabbit antibody targeting the CLDN4 (Claudin 4), which plays a critical role in the paracellular reabsorption of filtered chloride in the kidney collecting ducts. It specifically reacts with human CLDN4. It has been reported for use in Western Blot, Immunohistochemistry-Paraffin and Immunoprecipitation. The recommended dilutions of Western Blot, Immunohistochemistry-Paraffin and Immunoprecipitation is 1/500-1/1000, 1/50-1/100 and 1/20, respectively.

Specific Inquiry
  • Size:
  • Conjugation:
  • Endotoxin:
  • Purity:
  • Formats:
  • Isotype Switching:
  • Fc Engineering:
  • Modalities:
  • Gene Expression
  • Datasheet
  • MSDS
  • COA
Subcellular Location
Normal Tissue
RNA Expression

Specifications

  • Host Species
  • Rabbit
  • Type
  • Rabbit IgG
  • Specificity
  • Human CLDN4
  • Species Reactivity
  • Human
  • Clone
  • R06-4F2
  • Applications
  • WB, IHC-P, IP
  • Related Disease
  • Ovarian Cystadenoma; Williams-Beuren Syndrome

Product Property

  • Clonality
  • Monoclonal
  • Aggregation
  • < 5%
  • Format
  • Liquid
  • Buffer
  • PBS (pH 7.4), 150 mM NaCl and 50% glycerol
  • Preservative
  • 0.02% sodium azide
  • Storage
  • Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Shipping
  • Ice packs

Applications

  • Application Notes
  • WB: 1/500-1/1000
    IHC: 1/50-1/100
    IP: 1/20

Target

  • Alternative Names
  • CPER; CPE-R; CPETR; CPETR1; WBSCR8; hCPE-R
  • Long Name
  • Claudin 4
  • Cellular Localization
  • Cell junction, Cell membrane
  • Post Translation Modifications
  • Phosphorylated.
    Phosphorylation by EPHA2 is stimulated by EFNA1 and alters interaction with TJP1.
    (O14493-CLD4_HUMAN)
    Modification sites at PhosphoSitePlus (O14493)
    Modification sites at neXtProt (NX_O14493)
  • Function
  • Channel-forming tight junction protein that mediates paracellular chloride transport in the kidney. Plays a critical role in the paracellular reabsorption of filtered chloride in the kidney collecting ducts. Claudins play a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.

Recommended Products

Recommended Dilution Buffer

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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