Rabbit Anti-CNN1 Recombinant Antibody (VS3-CJ1026)
CAT#: VS3-CJ1026
This product is a rabbit antibody that recognizes human, mouse, rat, Dog, and Porcine CNN1.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to actin filaments.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/14263/120_G8_1_selected.jpg
Normal Tissue
Figure 2 High expression in smooth muscle
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/14263/ihc_selected.jpg
Normal Tissue
Figure 3 Low expression in skeletal muscle
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/14263/32474_B_1_6_val_selected.jpg
Normal Tissue
Figure 4 Smooth muscle
Smooth muscle cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/14263/32474_B_5_7.jpg
RNA Expression
Figure 5 RNA cell line category: Cell line enhanced (BJ, BJ hTERT+, BJ hTERT+ SV40 Large T+, BJ hTERT+ SV40 Large T+ RasG12V, HBF TERT88, K-562, SuSa, U-2 OS)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000130176-CNN1
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Specifications
- Immunogen
- Recombinant protein
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human, Mouse, Rat, Dog, Porcine CNN1
- Species Reactivity
- Human, Mouse, Rat, Dog, Porcine
- Applications
- WB, ICC, IF, IHC
- Conjugate
- Unconjugated
Product Property
- Purification
- Protein A affinity purified
- Purity
- >95% as determined by SDS-PAGE
- Format
- Liquid
- Buffer
- 40% Glycerol, 1% BSA, TBS, pH7.4.
- Preservative
- 0.05% Sodium Azide
- Storage
- Store at 4°C for short term. Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- This antibody has been tested for use in Western Blot, Immunocytochemistry, Immunofluorescence, Immunohistochemistry.
Target
- Alternative Names
- SMCC; Sm-Calp; HEL-S-14
- Gene ID
- 1264
- UniProt ID
- P51911
- Sequence Similarities
- Belongs to the calponin family.
- Cellular Localization
- Cytoskeleton, Focal adhesion
- Protein Refseq
- NP_001290.2; NP_001295270.1
- Function
- Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity (By similarity).
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Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
Isotype Control
- CAT
- Product Name
Secondary Antibody
- CAT
- Product Name
See other products for "CNN1"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-0738 | Hi-Affi™ Rabbit Anti-CNN1 Recombinant Antibody (clone DS738AB) | ELISA | Rabbit IgG |
| MOR-0078-FY | Rabbit Anti-CNN1 Recombinant Antibody (clone AFY0049) | ICC, IHC-P, WB | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-0218-CN | Rabbit Anti-CNN1 Recombinant Antibody (clone CBACN-080) | WB, IF, IHC | Rabbit IgG |
| ZG-0062J | Mouse Anti-CNN1 Recombinant Antibody (ZG-0062J) | IHC-P, IF | Mouse IgG |
| VS3-CJ1025 | Mouse Anti-CNN1 Recombinant Antibody (clone ABT-CALP) | IHC-P | Mouse IgG |
| VS3-XY509 | Mouse Anti-CNN1 Recombinant Antibody (clone 1H5B5) | ELISA, WB, IHC | Mouse IgG1 |
| VS3-XY510 | Mouse Anti-CNN1 Recombinant Antibody (clone 2E1) | ELISA, WB, IHC | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY1552 | Anti-CNN1 Immunohistochemistry Kit | IHC | |
| VS-0525-XY1553 | Anti-Mouse CNN1 Immunohistochemistry Kit | IHC | |
| VS-0525-XY1554 | Anti-Rat CNN1 Immunohistochemistry Kit | IHC |
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