Rabbit Anti-CTSD Recombinant Antibody (VS13-YC271) (CAT#: VS13-YC271)

• Immunogen
• Recombinant human Cathepsin D, aa 363-412.

• Host Species
• Rabbit

• Type
• Rabbit IgG

• Specificity
• Human and Mouse CTSD

• Species Reactivity
• Human, Mouse

• Applications
• WB, ICC, IF, IHC-P, IP

• Conjugate
• NONE

• Related Disease
• Ceroid Lipofuscinosis, Neuronal, and Neuronal Ceroid Lipofuscinosis

• Clonality
• Monoclonal

• Purification
• Protein A purified

• Format
• Liquid

• Concentration
• Please refer to the vial label for the specific concentration.

• Buffer
• TBS (pH 7.4) containing 40% Glycerol and 0.05% BSA.

• Preservative
• 0.05% Sodium azide

• Storage
• Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

• Shipping
• Shipping with ice pack.

• Application Notes
• Western blot (WB): 1/500-1/2000
  Immunocytochemistry (ICC): 1/100-1/500
  Immunohistochemistry-paraffin (IHC-P): 1/100-1/500

• Alternative Names
• Cathepsin D; Ceroid-Lipofuscinosis, Neuronal 10; EC 3.4.23.5; CPSD; Epididymis Secretory Sperm Binding Protein Li 130P; Cathepsin D (Lysosomal Aspartyl Protease);

• Gene ID
• 1509

• UniProt ID
• P07339

• Long Name
• Cathepsin D

• Cellular Localization
• Secreted; Lysosome; Melanosome

• Protein Refseq
• NP_001900.1

• Function
• Acid protease active in intracellular protein breakdown. Plays a role in APP processing following cleavage and activation by ADAM30 which leads to APP degradation. Involved in the pathogenesis of several diseases such as breast cancer and possibly Alzheimer disease.

Secondary Antibody

• 2ND-059CQ
• Goat Anti-Rabbit IgG (H&L) Antibody

• 2ND-061CQ
• Sheep Anti-Rabbit IgG (H&L) Antibody

Isotype Control

• MOB-208CQ
• Rabbit IgG Isotype Control Antibody

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