Rabbit Anti-CTSD Recombinant Antibody (VS13-YC271) (CAT#: VS13-YC271)
The Rabbit Anti-CTSD Recombinant Antibody is specific for human and mouse CTSD. CTSD, cathepsin D, affects metabolic and immune pathways, associated with neuronal and metabolic disorders through protease interactions. The anti-CTSD antibody can be used for Western blot (1/500-1/2000), Immunocytochemistry (1/100-1/500), Immunohistochemistry-paraffin (1/100-1/500).
Specific Inquiry
Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
We require custom production
Normal Tissue
RNA Expression
Figure 1 Cerebral cortex
(Endothelial cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Neuronal cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/109/2425_B_8_5.jpg
(Endothelial cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Neuronal cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/109/2425_B_8_5.jpg
Figure 2 Lung
(Macrophages
Staining: High
Intensity: Strong
Quantity:>75%)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/109/2425_A_2_4.jpg
(Macrophages
Staining: High
Intensity: Strong
Quantity:>75%)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/109/2425_A_2_4.jpg
Figure 3 Colon
(Endocrine cells
Staining: Medium
Intensity: Moderate
Enterocytes
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Mucosal lymphoid cells
Staining: High
Intensity: Strong
Quantity: 75%-25%
Peripheral nerve/ganglion
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/109/2425_A_8_3.jpg
(Endocrine cells
Staining: Medium
Intensity: Moderate
Enterocytes
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Mucosal lymphoid cells
Staining: High
Intensity: Strong
Quantity: 75%-25%
Peripheral nerve/ganglion
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/109/2425_A_8_3.jpg
Figure 4 Liver
(Hepatocytes
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/109/2425_A_9_4.jpg
(Hepatocytes
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/109/2425_A_9_4.jpg
Figure 5 Kidney
(Cells in glomeruli
Staining: High
Intensity: Strong
Quantity: 75%-25%
Collecting ducts
Staining: High
Intensity: Strong
Quantity:>75%
Distal tubules
Staining: High
Intensity: Strong
Quantity:>75%)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/109/2425_A_8_5.jpg
(Cells in glomeruli
Staining: High
Intensity: Strong
Quantity: 75%-25%
Collecting ducts
Staining: High
Intensity: Strong
Quantity:>75%
Distal tubules
Staining: High
Intensity: Strong
Quantity:>75%)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/109/2425_A_8_5.jpg
Figure 6 Testis
(Leydig cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Sertoli cells
Staining: Medium
Intensity: Strong
Quantity: <25%)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/109/2425_A_6_6.jpg
(Leydig cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Sertoli cells
Staining: Medium
Intensity: Strong
Quantity: <25%)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/109/2425_A_6_6.jpg
Figure 7 RNA cell line category: Cell line enhanced (CAPAN-2, hTERT-RPE1, SK-BR-3)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000117984-CTSD
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000117984-CTSD
Figure 7 RNA cell line category: Cell line enhanced (CAPAN-2, hTERT-RPE1, SK-BR-3)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000117984-CTSD
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000117984-CTSD
Specifications
- Immunogen
- Recombinant human Cathepsin D, aa 363-412.
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human and Mouse CTSD
- Species Reactivity
- Human, Mouse
- Applications
- WB, ICC, IF, IHC-P, IP
- Conjugate
- NONE
- Related Disease
- Ceroid Lipofuscinosis, Neuronal, and Neuronal Ceroid Lipofuscinosis
Product Property
- Clonality
- Monoclonal
- Purification
- Protein A purified
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- TBS (pH 7.4) containing 40% Glycerol and 0.05% BSA.
- Preservative
- 0.05% Sodium azide
- Storage
- Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Shipping with ice pack.
Applications
- Application Notes
- Western blot (WB): 1/500-1/2000
Immunocytochemistry (ICC): 1/100-1/500
Immunohistochemistry-paraffin (IHC-P): 1/100-1/500
Target
- Alternative Names
- Cathepsin D; Ceroid-Lipofuscinosis, Neuronal 10; EC 3.4.23.5; CPSD; Epididymis Secretory Sperm Binding Protein Li 130P; Cathepsin D (Lysosomal Aspartyl Protease);
- Gene ID
- 1509
- UniProt ID
- P07339
- Long Name
- Cathepsin D
- Cellular Localization
- Secreted; Lysosome; Melanosome
- Protein Refseq
- NP_001900.1
- Function
- Acid protease active in intracellular protein breakdown. Plays a role in APP processing following cleavage and activation by ADAM30 which leads to APP degradation. Involved in the pathogenesis of several diseases such as breast cancer and possibly Alzheimer disease.
Recommended Products
Secondary Antibody
Isotype Control
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
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Antibody Magnetic Beads
| CAT | Product Name | Application | Type |
|---|---|---|---|
| DrMAB-1052 | Mouse Anti-CTSD Recombinant Antibody (clone YC031); Fab Fragment | ELISA | Mouse Fab |
| HPAB-0399-CN-F(E) | Human Anti-CTSD Recombinant Antibody; Fab Fragment (HPAB-0399-CN-F(E)) | ELISA, IF, IP, Neut | Human Fab |
| HPAB-0400-CN-F(E) | Human Anti-CTSD Recombinant Antibody; Fab Fragment (HPAB-0400-CN-F(E)) | ELISA, IF, IP, Neut | Human Fab |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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