Human Anti-DNA Recombinant Antibody (clone 71F12) (CAT#: PABC-515)
This product is a recombinant Human antibody that can recognize DNA. The antibody is capable to bind to both single-stranded (ss) and dsDNA at high affinity.
Specific Inquiry
ELISA
Figure 1 Reversion assay in ELISA.
The reactivity of patient-derived mutated (black: SHM [+]) or reverted (red: SHM [-]) antibodies in ELISA for the respective self-antigens are shown.
Sakakibara, S., Arimori, T., Yamashita, K., Jinzai, H., Motooka, D., Nakamura, S., ... & Narazaki, M. (2017). Clonal evolution and antigen recognition of anti-nuclear antibodies in acute systemic lupus erythematosus. Scientific reports, 7(1), 16428.
IF
Figure 2 Reversion assay in IFA.
Sakakibara, S., Arimori, T., Yamashita, K., Jinzai, H., Motooka, D., Nakamura, S., ... & Narazaki, M. (2017). Clonal evolution and antigen recognition of anti-nuclear antibodies in acute systemic lupus erythematosus. Scientific reports, 7(1), 16428.
Specifications
- Host Species
- Human
- Type
- Human IgG2, λ
- Clone
- 71F12
- Applications
- ELISA, IF
- Related Disease
- Systemic lupus erythematosus (SLE)
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- This antibody has been tested for use in Enzyme-linked Immunosorbent Assay and Immunofluorescence. It's recommended that the optimal antibody concentration, dilution, incubition time, etc. be carefully titrated in specific assays.
Target
- Alternative Names
- DNA; deoxyribonucleic acid
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
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Mouse Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABX-048 | Recombinant Mouse Anti-DNA Antibody | WB, ELISA, FuncS | IgG |
| PABX-048-F (E) | Recombinant Mouse Anti-DNA Antibody Fab Fragment | WB, ELISA, FuncS | Fab |
Humanized Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABX-048-S (P) | Recombinant Mouse Anti-DNA Antibody scFv Fragment | WB, ELISA, FuncS | scFv |
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| FAMAB-0075CQ | Mouse Anti-DNA Recombinant Antibody (clone 16-13) | ELISA | Mouse IgG2a |
| FAMAB-0076CQ | Mouse Anti-DNA Recombinant Antibody (clone 1A11) | ELISA | Mouse IgG2b |
| FAMAB-0077CQ | Mouse Anti-DNA Recombinant Antibody (clone 1E81) | ELISA | Mouse IgG2a |
| FAMAB-0078CQ | Mouse Anti-DNA Recombinant Antibody (clone 2F2) | ELISA | Mouse IgG2b |
| FAMAB-0079CQ | Mouse Anti-DNA Recombinant Antibody (clone 3E12) | ELISA | Mouse IgG1 |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| FAMAB-0075CQ-F(E) | Mouse Anti-DNA Recombinant Antibody (clone 16-13); Fab Fragment | ELISA | Mouse Fab |
| FAMAB-0076CQ-F(E) | Mouse Anti-DNA Recombinant Antibody (clone 1A11); Fab Fragment | ELISA | Mouse Fab |
| FAMAB-0077CQ-F(E) | Mouse Anti-DNA Recombinant Antibody (clone 1E81); Fab Fragment | ELISA | Mouse Fab |
| FAMAB-0078CQ-F(E) | Mouse Anti-DNA Recombinant Antibody (clone 2F2); Fab Fragment | ELISA | Mouse Fab |
| FAMAB-0079CQ-F(E) | Mouse Anti-DNA Recombinant Antibody (clone 3E12); Fab Fragment | ELISA | Mouse Fab |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0271-YJ-S(P) | Mouse Anti-DNA Recombinant Antibody; scFv Fragment (HPAB-0271-YJ-S(P)) | FuncS | Mouse scFv |
| FAMAB-0034WJ-S(P) | Human Anti-DNA Recombinant Antibody (clone T33-4); scFv Fragment | WB | Human scFv |
| FAMAB-0035WJ-S(P) | Human Anti-DNA Recombinant Antibody (clone T33-16); scFv Fragment | WB | Human scFv |
| FAMAB-0036WJ-S(P) | Human Anti-DNA Recombinant Antibody (clone T33-17); scFv Fragment | WB | Human scFv |
| FAMAB-0046WJ-S(P) | Human Anti-DNA Recombinant Antibody (clone O-81); scFv Fragment | WB | Human scFv |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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