Human Anti-DNA Recombinant Antibody (clone 71F12) (CAT#: PABC-515)
This product is a recombinant Human antibody that can recognize DNA. The antibody is capable to bind to both single-stranded (ss) and dsDNA at high affinity.
Specific Inquiry
Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
We require custom production
ELISA
Figure 1 Reversion assay in ELISA.
The reactivity of patient-derived mutated (black: SHM [+]) or reverted (red: SHM [-]) antibodies in ELISA for the respective self-antigens are shown.
Sakakibara, S., Arimori, T., Yamashita, K., Jinzai, H., Motooka, D., Nakamura, S., ... & Narazaki, M. (2017). Clonal evolution and antigen recognition of anti-nuclear antibodies in acute systemic lupus erythematosus. Scientific reports, 7(1), 16428.
IF
Figure 2 Reversion assay in IFA.
Sakakibara, S., Arimori, T., Yamashita, K., Jinzai, H., Motooka, D., Nakamura, S., ... & Narazaki, M. (2017). Clonal evolution and antigen recognition of anti-nuclear antibodies in acute systemic lupus erythematosus. Scientific reports, 7(1), 16428.
Specifications
- Host Species
- Human
- Type
- Human IgG2, λ
- Clone
- 71F12
- Applications
- ELISA, IF
- Related Disease
- Systemic lupus erythematosus (SLE)
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- This antibody has been tested for use in Enzyme-linked Immunosorbent Assay and Immunofluorescence. It's recommended that the optimal antibody concentration, dilution, incubition time, etc. be carefully titrated in specific assays.
Target
- Alternative Names
- DNA; deoxyribonucleic acid
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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ScFv-Fc Chimera Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABX-048 | Recombinant Mouse Anti-DNA Antibody | WB, ELISA, FuncS | IgG |
| PABX-048-F (E) | Recombinant Mouse Anti-DNA Antibody Fab Fragment | WB, ELISA, FuncS | Fab |
Customer Reviews and Q&As
Customer Review
Q&As
Complete Procedures Available
The offered protocols ensured that the product was successfully implemented in my tests because they were clear and easy to follow. It streamlined and expedited my work.
Simple Data Visualization
This tool produces a comprehensible and easily interpreted data visualization. It provides high-quality results that are easy to analyze.
Simple to Manage
This antibody was easy to work with and straightforward. It is a dependable reagent because the performance was consistently high and the directions were clear.
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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