AbPlus™ Anti-DSG2 Magnetic Beads (10D2) (CAT#: VS-0424-XY80)

• Applications
• Immunoprecipitation, Protein Purification

• Matrix
• Magrose bead (> 50 μmol/mL gel)

• Bead Ligand
• Anti-DSG2 specific antibody (10D2)

• Target
• DSG2

• Immunogen
• A fusion protein of human DSG2 (aa 37-164) with a proprietary tag

• Target Species
• Human, Predicted to work with: Mouse

• Antibody Clone
• 10D2

• Bead Capacity
• 20-30 mg/mL binding antibody

• Bead size
• 10-37 μm

• Stability
• pH 2-14

• Format
• 20% Suspension

• Buffer
• PBS, pH 7.4, with 1% BSA

• Preservative
• 0.03% Proclin 300

• Storage
• Stored at 4°C, and is stable for up to 2 years. Do not centrifuge, dry or freeze the magnetic beads.

• Application Notes
• The beads are in suspension and will settle upon storage. Prior to use, mix the vial gently (do not vortex) to ensure delivery of proper bead volume.

• Introduction
• DSG2 encodes a member of the desmoglein family and cadherin cell adhesion molecule superfamily of proteins. Desmogleins are calcium-binding transmembrane glycoprotein components of desmosomes, cell-cell junctions between epithelial, myocardial, and other cell types. The encoded preproprotein is proteolytically processed to generate the mature glycoprotein. This gene is present in a gene cluster with other desmoglein gene family members on chromosome 18. Mutations in this gene have been associated with arrhythmogenic right ventricular dysplasia, familial, 10.

• Alternative Names
• HDGC; CDHF5; desmoglein-2; Desmoglein 2; cadherin family member 5

• Gene ID
• 1829

• UniProt ID
• Q14126

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