CytoStream™ Rabbit Anti-DSG2 Recombinant Antibody (VS13-YC325)
CAT#: VS13-YC325
The CytoStream™ Rabbit Anti-DSG2 Recombinant Antibody is specific for human, mouse and rat DSG2. DSG2 encodes a desmosomal cadherin involved in cell adhesion, linked to cardiac dysplasia syndromes through junction integrity in cell types like epithelial and myocardial cells. The anti-DSG2 antibody was developed and selected by our CytoStream™ platform and the mAb is recommended for use in flow cytometry staining (1/50-1/100).
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line A-431
Immunofluorescent staining of human cell line A-431 shows localization to cell junctions & vesicles.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/4896/1685_D1_1_selected.jpg
Subcellular Location
Figure 2 IF staining of human cell line A-431
Immunofluorescent staining of human cell line A-431 shows localization to cell junctions.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/25122/672_G5_4_selected.jpg
Normal Tissue
Figure 3 Rectum
High expression in rectum
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/4896/15170_A_6_3_val_selected.jpg
Normal Tissue
Figure 4 Small intestine
High expression in small intestine
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/25122/55672_A_6_2_val_selected.jpg
Normal Tissue
Figure 5 Kidney
Bowman's capsule Staining: High Intensity: Strong Quantity:>75% Collecting ducts Staining: High Intensity: Strong Quantity: 75%-25% Distal tubules Staining: High Intensity: Strong Quantity:>75%
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/25122/55672_A_8_5.jpg
Normal Tissue
Figure 6 Parathyroid gland
Glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/25122/55672_A_1_8.jpg
RNA Expression
Figure 7 RNA cell line category: Cell line enhanced (CAPAN-2, HaCaT, HBEC3-KT, hTERT-HME1, OE19)
Cell lines ordered by descending RNA expression order
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000046604-DSG2
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Specifications
- Immunogen
- Recombinant human Desmoglein 2.
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human, Mouse and Rat DSG2
- Species Reactivity
- Human, Mouse, Rat
- Applications
- WB, IHC-P, ICC, IF, FC
- Conjugate
- NONE
Product Property
- Clonality
- Monoclonal
- Purification
- Affinity Chromatography purified
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS (pH 7.4) containing 150 mM NaCl and 50% Glycerol.
- Preservative
- 0.02% Sodium azide
- Storage
- Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Shipping with ice pack.
Applications
- Application Notes
- Western blot (WB): 1/500-1/1000
Immunohistochemistry (IHC): 1/50-1/100
Immunofluorescence (IF): 1/50-1/200
Flow cytometry (FC): 1/50-1/100
Target
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
Secondary Antibody
- CAT
- Product Name
Isotype Control
- CAT
- Product Name
See other products for "DSG2"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2195MZ | Recombinant Mouse Anti-Human DSG2 Antibody (clone 4H243) | ICC, IF, IHC-P, IP, WB | Mouse antibody |
| HPAB-N0063-YC | Mouse Anti-DSG2 Recombinant Antibody (HPAB-N0063-YC) | FC, WB | Mouse IgG |
| HPAB-N0064-YC | Mouse Anti-DSG2 Recombinant Antibody (HPAB-N0064-YC) | FC, WB | Mouse IgG |
| HPAB-0405-FY | Human Anti-DSG2 Recombinant Antibody (HPAB-0405-FY) | FC, IP | Human IgG |
| MOB-054YJL | Mouse Anti-DSG2 Recombinant Antibody (clone CBD009) | ICC, IF, WB | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1054 | Hi-Affi™ Rabbit Anti-DSG2 Recombinant Antibody (clone DS1054AB) | WB, IP, FC | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-N0063-YC-S(P) | Mouse Anti-DSG2 Recombinant Antibody; scFv Fragment (HPAB-N0063-YC-S(P)) | FC, WB | Mouse scFv |
| HPAB-N0064-YC-S(P) | Mouse Anti-DSG2 Recombinant Antibody; scFv Fragment (HPAB-N0064-YC-S(P)) | FC, WB | Mouse scFv |
| HPAB-0405-FY-S(P) | Human Anti-DSG2 Recombinant Antibody; scFv Fragment (HPAB-0405-FY-S(P)) | FC, IP | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-N0063-YC-F(E) | Mouse Anti-DSG2 Recombinant Antibody; Fab Fragment (HPAB-N0063-YC-F(E)) | FC, WB | Mouse Fab |
| HPAB-N0064-YC-F(E) | Mouse Anti-DSG2 Recombinant Antibody; Fab Fragment (HPAB-N0064-YC-F(E)) | FC, WB | Mouse Fab |
| HPAB-0405-FY-F(E) | Human Anti-DSG2 Recombinant Antibody; Fab Fragment (HPAB-0405-FY-F(E)) | FC, IP | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0424-XY80 | AbPlus™ Anti-DSG2 Magnetic Beads (10D2) | IP, Protein Purification | |
| VS-0724-YC1365 | AbPlus™ Anti-DSG2 Magnetic Beads (VS-0724-YC1365) | IP, Protein Purification |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0225-XY101 | CytoStream™ Mouse Anti-DSG2 Recombinant Antibody (clone 6D8) | FC | Mouse IgG1, kappa |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY699 | Anti-DSG2 Immunohistochemistry Kit | IHC | |
| VS-0525-XY2094 | Anti-Human DSG2 Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-FY21 | Human Anti-DSG2 scFv-Fc Chimera (VS-0425-FY21) | FC, IP | Human IgG1, scFv-Fc |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC466 | Recombinant Anti-DSG2 Vesicular Antibody, EV Displayed (VS-0425-YC466) | ELISA, FC, Cell-uptake |
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