AbPlus™ Anti-DSG2 Magnetic Beads (VS-0724-YC1365) (CAT#: VS-0724-YC1365)
The AbPlus Anti-DSG2 Magnetic Beads (VS-0724-YC1365) is an innovative affinity resin which is bound with anti-DSG2 specific antibody. The beads were designed for small-scale affinity purification and immunoprecipitation (IP) of DSG2 protein under native and denaturing conditions.
Specific Inquiry
Subcellular Location
Normal Tissue
RNA Expression

Figure 1 IF staining of human cell line A-431
(Immunofluorescent staining of human cell line A-431 shows localization to cell junctions & vesicles.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4896/1685_D1_1_selected.jpg
(Immunofluorescent staining of human cell line A-431 shows localization to cell junctions & vesicles.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4896/1685_D1_1_selected.jpg

Figure 2 IF staining of human cell line A-431
(Immunofluorescent staining of human cell line A-431 shows localization to cell junctions.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/25122/672_G5_4_selected.jpg
(Immunofluorescent staining of human cell line A-431 shows localization to cell junctions.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/25122/672_G5_4_selected.jpg

Figure 3 Rectum
(High expression in rectum)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4896/15170_A_6_3_val_selected.jpg
(High expression in rectum)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4896/15170_A_6_3_val_selected.jpg

Figure 4 Small intestine
(High expression in small intestine)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/25122/55672_A_6_2_val_selected.jpg
(High expression in small intestine)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/25122/55672_A_6_2_val_selected.jpg

Figure 5 Kidney
(Bowman's capsule Staining: High Intensity: Strong Quantity:>75% Collecting ducts Staining: High Intensity: Strong Quantity: 75%-25% Distal tubules Staining: High Intensity: Strong Quantity:>75%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/25122/55672_A_8_5.jpg
(Bowman's capsule Staining: High Intensity: Strong Quantity:>75% Collecting ducts Staining: High Intensity: Strong Quantity: 75%-25% Distal tubules Staining: High Intensity: Strong Quantity:>75%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/25122/55672_A_8_5.jpg

Figure 6 Parathyroid gland
(Glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/25122/55672_A_1_8.jpg
(Glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/25122/55672_A_1_8.jpg

Figure 7 RNA cell line category: Cell line enhanced (CAPAN-2, HaCaT, HBEC3-KT, hTERT-HME1, OE19)
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000046604-DSG2
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000046604-DSG2
Specifications
- Applications
- Immunoprecipitation, Protein Purification
- Matrix
- Magnetic bead
- Bead Ligand
- Anti-DSG2 specific antibody
- Target
- DSG2
- Immunogen
- Recombinant human Desmoglein-2/DSG2 fragment derived from E. coli.
- Target Species
- Human
- Bead Capacity
- 40 mg/mL
- Bead size
- 25 μm
- Format
- Suspension
- Concentration
- 2 mg/mL
- Buffer
- PBS, pH 7.4
- Preservative
- 0.1% Sodium azide
- Storage
- Stored at 4°C, and is stable for up to 2 years. Do not centrifuge, dry or freeze the magnetic beads.
Applications
- Application Notes
- The beads are in suspension and will settle upon storage. Prior to use, mix the vial gently (do not vortex) to ensure delivery of proper bead volume.
Target
- Introduction
- This gene encodes a member of the desmoglein family and cadherin cell adhesion molecule superfamily of proteins. Desmogleins are calcium-binding transmembrane glycoprotein components of desmosomes, cell-cell junctions between epithelial, myocardial, and other cell types. The encoded preproprotein is proteolytically processed to generate the mature glycoprotein. This gene is present in a gene cluster with other desmoglein gene family members on chromosome 18. Mutations in this gene have been associated with arrhythmogenic right ventricular dysplasia, familial, 10. [provided by RefSeq, Jan 2016]
- Alternative Names
- Desmoglein 2; Cadherin Family Member 5; CDHF5; HDGC; Desmoglein-2;
- Gene ID
- 1829
- UniProt ID
- Q14126
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
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Extracellular Vesicle (EV) Antibody Products
CAT | Product Name | Application | Type |
---|---|---|---|
MOB-2195MZ | Recombinant Mouse Anti-Human DSG2 Antibody (clone 4H243) | ICC/IF, IHC-P, IP, WB | Mouse antibody |
HPAB-0405-FY | Human Anti-DSG2 Recombinant Antibody (HPAB-0405-FY) | FC, IP | Human IgG |
MOB-054YJL | Mouse Anti-DSG2 Recombinant Antibody (clone CBD009) | ICC, IF, WB | Mouse IgG1 |
VS1-YJ45 | Mouse Anti-DSG2 Recombinant Antibody (clone 10D2) | IB, IF, IP | Mouse IgG1 |
VS1-YJ46 | Mouse Anti-DSG2 Recombinant Antibody (clone 7H9) | WB | Mouse IgG1 |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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