Human Anti-DSG2 scFv-Fc Chimera (VS-0425-FY21) (CAT#: VS-0425-FY21)
This anti-DSG2 scFv-Fc antibody is designed to specifically target desmoglein 2 (Dsg2), a crucial transmembrane glycoprotein found within desmosomal junctions. Given the unique expression of Dsg2 on undifferentiated human pluripotent stem cells, this antibody serves as a valuable tool for their precise detection and isolation.
Specific Inquiry
Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
We require custom production
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line A-431
(Immunofluorescent staining of human cell line A-431 shows localization to cell junctions & vesicles.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4896/1685_D1_1_selected.jpg
(Immunofluorescent staining of human cell line A-431 shows localization to cell junctions & vesicles.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4896/1685_D1_1_selected.jpg
Figure 2 IF staining of human cell line A-431
(Immunofluorescent staining of human cell line A-431 shows localization to cell junctions.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/25122/672_G5_4_selected.jpg
(Immunofluorescent staining of human cell line A-431 shows localization to cell junctions.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/25122/672_G5_4_selected.jpg
Figure 3 Rectum
(High expression in rectum)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4896/15170_A_6_3_val_selected.jpg
(High expression in rectum)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4896/15170_A_6_3_val_selected.jpg
Figure 4 Small intestine
(High expression in small intestine)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/25122/55672_A_6_2_val_selected.jpg
(High expression in small intestine)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/25122/55672_A_6_2_val_selected.jpg
Figure 5 Kidney
(Bowman's capsule Staining: High Intensity: Strong Quantity:>75% Collecting ducts Staining: High Intensity: Strong Quantity: 75%-25% Distal tubules Staining: High Intensity: Strong Quantity:>75%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/25122/55672_A_8_5.jpg
(Bowman's capsule Staining: High Intensity: Strong Quantity:>75% Collecting ducts Staining: High Intensity: Strong Quantity: 75%-25% Distal tubules Staining: High Intensity: Strong Quantity:>75%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/25122/55672_A_8_5.jpg
Figure 6 Parathyroid gland
(Glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/25122/55672_A_1_8.jpg
(Glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/25122/55672_A_1_8.jpg
Figure 7 RNA cell line category: Cell line enhanced (CAPAN-2, HaCaT, HBEC3-KT, hTERT-HME1, OE19)
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000046604-DSG2
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000046604-DSG2
Specifications
- Immunogen
- The immunogen is the H9 cell line.
- Host Species
- Human
- Type
- Human IgG1, scFv-Fc
- Specificity
- Human DSG2
- Species Reactivity
- Human
- Applications
- Flow Cytometry, Immunoprecipitation
- Related Disease
- Autoimmune disease
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Ice packs
Applications
- Application Notes
- The optimal dilution concentration is determined by the experiment.
Target
- Alternative Names
- Desmoglein 2; Cadherin Family Member 5; CDHF5; HDGC; Desmoglein-2
- Gene ID
- 1829
- UniProt ID
- Q14126
- Long Name
- Desmoglein 2
- Cellular Localization
- Cell membrane, Cell junction, desmosome
- Post Translation Modifications
- Palmitoylated by ZDHHC5 at the plasma membrane.
Glycosylation at Asn112, Asn182, Asn309, Asn462, Asn514, and Asn789
Ubiquitination at Lys706, Lys746, and Lys832
Modification sites at PhosphoSitePlus
Glycosylation from GlyConnect DSG2_HUMAN (1172)
Glycosylation from GlyGen 12 sites, 40 N-linked glycans (5 sites), 2 O-linked glycans (3 sites)
- Protein Refseq
- XP_047293271.1; XP_054174212.1; NP_001934.2
- Function
- Component of intercellular desmosome junctions.
Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "DSG2"
Select a product category from the dropdown menu below to view related products.
Please select product type
IgG Antibody Products
Rabbit Monoclonal Antibody Products
ScFv Antibody Products
Fab Antibody Products
Antibody Magnetic Beads
Flow Cytometry (FC) related Reagents and Kits: Empowering Cell Function Research
IHC Kit and Antibody Products: Precision Tools for Immunohistochemistry
Extracellular Vesicle (EV) Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-3317z | Mouse Anti-DSG2 Recombinant Antibody (clone 19F5) | WB, IP, IF | Mouse IgG1, κ |
| MRO-0474-CN | Rabbit Anti-DSG2 Recombinant Antibody (clone JB96-37) | WB, IHC, FC | Rabbit IgG |
| HPAB-N0063-YC | Mouse Anti-DSG2 Recombinant Antibody (HPAB-N0063-YC) | FC, WB | Mouse IgG |
| HPAB-N0064-YC | Mouse Anti-DSG2 Recombinant Antibody (HPAB-N0064-YC) | FC, WB | Mouse IgG |
| VS1-YJ45 | Mouse Anti-DSG2 Recombinant Antibody (clone 10D2) | IB, IF, IP | Mouse IgG1 |
Customer Reviews and Q&As
There are currently no Customer reviews or questions for VS-0425-FY21. Click the button above to contact us or submit your feedback about this product.
Popular products with customers
Application: WB, ELISA, FC, IP, FuncS, IF, Neut
Application: ELISA, IP, FC, FuncS, Neut, IF, IHC
Application: FuncS, IF, Neut, ELISA, FC, IP, IHC
Application: WB, FC, IP, ELISA, Neut, FuncS, IF
Application: FuncS, IF, Neut, ELISA, FC, IP, WB
Application: Neut, ELISA, IF, IP, FuncS, FC, ICC
Application: ELISA, FC, IP, FuncS, IF, Neut, ICC
Application: ELISA, WB, BLI, SPR
Application: ELISA, Block, WB, FC, IP
Application: ELISA, Neut, FuncS
For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
