Mouse Anti-EDAR Recombinant Antibody (clone EDAR8) (CAT#: FAMAB-0089JF)
Recombinant mouse monoclonal antibody specially binds to ectodysplasin A receptor. This anti-EDAR antibody (EDAR8) can be wildly used in XLHED or other EDAR-related applications in humans.
Specific Inquiry
WB
Figure 1 Western blot analysis of skin samples of five mice of different founder lines and one control mouse using antibodies against Edar.
The specific ca. 60-kDa Edar expression is marked by an arrow.
Pispa, J., Mustonen, T., Mikkola, M. L., Kangas, A. T., Koppinen, P., Lukinmaa, P. L., ... & Thesleff, I. (2004). Tooth patterning and enamel formation can be manipulated by misexpression of TNF receptor Edar. Developmental dynamics: an official publication of the American Association of Anatomists, 231(2), 432-440.
IHC
Figure 2 Expression levels of the keratin 14 –Edar transgene.
Keratin 14-Edar cDNA expression construct. K14, keratin 14 promoter.
Pispa, J., Mustonen, T., Mikkola, M. L., Kangas, A. T., Koppinen, P., Lukinmaa, P. L., ... & Thesleff, I. (2004). Tooth patterning and enamel formation can be manipulated by misexpression of TNF receptor Edar. Developmental dynamics: an official publication of the American Association of Anatomists, 231(2), 432-440.
ELISA
Figure 3 Parallelism was compared between the standard bovine NfH spiked into buffer (open circles, dotted line) and neat CSF (closed circles, solid line) by serial dilutions of four CSF samples.
Dots do represent the mean fluorescent intensity (MFI) ± SD of four CSF samples.
Koel-Simmelink, M. J., Vennegoor, A., Killestein, J., Blankenstein, M. A., Norgren, N., Korth, C., & Teunissen, C. E. (2014). The impact of pre-analytical variables on the stability of neurofilament proteins in CSF, determined by a novel validated SinglePlex Luminex assay and ELISA. Journal of Immunological Methods, 402(1-2), 43-49.
Specifications
- Immunogen
- mEDAR-Fc
- Host Species
- Mouse
- Type
- Mouse IgG1
- Specificity
- Human EDAR; mouse EDAR; dog EDAR; rat EDAR; mouse EDAR; chicken EDAR
- Species Reactivity
- Human, Mouse, Canine, Rat, Chicken
- Clone
- EDAR8
- Applications
- WB, ELISA, IHC
- Related Disease
- X-linked hypohidrotic ectodermal dysplasia
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- The EDAR antibody has been reported in applications of Western Blot, Enzyme-linked Immunosorbent Assay, Immunohistochemistry.
Target
- Alternative Names
- DL; ED3; ED5; ED1R; EDA3; HRM1; EDA1R; ECTD10A; ECTD10B; EDA-A1R
- Gene ID
- 10913
- UniProt ID
- Q9UNE0
- Function
- Agonist
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1090 | Hi-Affi™ Rabbit Anti-EDAR Recombinant Antibody (clone DS1090AB) | WB, FC | Rabbit IgG |
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0045-LS | Human Anti-EDAR Recombinant Antibody (HPAB-0045-LS) | ELISA, WB, FC | Human IgG1 |
| HPAB-0046-LS | Human Anti-EDAR Recombinant Antibody (HPAB-0046-LS) | ELISA, WB, FC | Human IgG2b |
| HPAB-0047-LS | Human Anti-EDAR Recombinant Antibody (HPAB-0047-LS) | ELISA, WB, FC | Human IgG2a |
| HPAB-0048-LS | Human Anti-EDAR Recombinant Antibody (HPAB-0048-LS) | ELISA, WB, FC | Human IgG1 |
| HPAB-J0065-YC | Human Anti-EDAR Recombinant Antibody (HPAB-J0065-YC) | ELISA, WB, FC, Agonist | Human IgG1 |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0045-LS-S(P) | Human Anti-EDAR Recombinant Antibody; scFv Fragment (HPAB-0045-LS-S(P)) | ELISA, WB, FC | Human scFv |
| HPAB-0046-LS-S(P) | Human Anti-EDAR Recombinant Antibody; scFv Fragment (HPAB-0046-LS-S(P)) | ELISA, WB, FC | Human scFv |
| HPAB-0047-LS-S(P) | Human Anti-EDAR Recombinant Antibody; scFv Fragment (HPAB-0047-LS-S(P)) | ELISA, WB, FC | Human scFv |
| HPAB-0048-LS-S(P) | Human Anti-EDAR Recombinant Antibody; scFv Fragment (HPAB-0048-LS-S(P)) | ELISA, WB, FC | Human scFv |
| FAMAB-0089JF-F(E) | Mouse Anti-EDAR Recombinant Antibody (clone EDAR8); Fab Fragment | WB, FACS, ELISA, FuncS | Mouse Fab |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-J0065-YC-S(P) | Human Anti-EDAR Recombinant Antibody; scFv Fragment (HPAB-J0065-YC-S(P)) | ELISA, WB, FC, Agonist | Human scFv |
| HPAB-J0066-YC-S(P) | Human Anti-EDAR Recombinant Antibody; scFv Fragment (HPAB-J0066-YC-S(P)) | ELISA, WB, FC, Agonist, FuncS | Human scFv |
| HPAB-J0067-YC-S(P) | Human Anti-EDAR Recombinant Antibody; scFv Fragment (HPAB-J0067-YC-S(P)) | ELISA, Agonist | Human scFv |
| HPAB-J0068-YC-S(P) | Human Anti-EDAR Recombinant Antibody; scFv Fragment (HPAB-J0068-YC-S(P)) | ELISA, Agonist | Human scFv |
| FAMAB-0090JF-S(P) | Mouse Anti-EDAR Recombinant Antibody (clone EDAR9); scFv Fragment | WB, FACS, ELISA, FuncS | Mouse scFv |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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