Human Anti-Env Antibody (clone PGT121), mRNA
CAT#: PABZ-203-mRNA
This mRNA encodes a Human antibody against Env. It contains two mRNAs that encode for the heavy and light chains of the antibody.
Specifications
- Immunogen
- HIV-1 gp160; envelope glycoprotein
- Host Species
- Human
- Specificity
- HIV1 Env
- Species Reactivity
- Human immunodeficiency virus 1
- Clone
- PGT121
Product Property
- Purity
- >95%
- Storage
- Store at -20°C.
Target
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Potent Neutralization
The PGT121 mRNA is amazing in its ability to neutralize HIV-1; I've utilized it in my studies. In our in vitro experiments, we saw a notable decrease in viral replication.
Highly Specific Binding
PGT121 is a dependable option for in-depth research because it continuously demonstrated good specificity and binding affinity to HIV-1 Env proteins in our ELISA experiments.
Great for Research
This product has greatly improved our knowledge of interactions between the HIV-1 envelope. In terms of efficacy and specificity, the PGT121 clone is among the best.
Q&As
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What is the primary application of the Human Anti-Env Antibody (clone PGT121), mRNA?
A: The primary application is for the detection and neutralization of HIV-1 envelope proteins in vitro. This antibody can be used in various assays to study HIV-1 infection and immune responses.
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What controls should be used in experiments with PGT121 mRNA?
A: Recommended controls include cells transfected with an irrelevant or empty mRNA construct and non-transfected cells to validate specificity and transfection efficiency.
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How long does antibody expression last after transfection?
A: Antibody expression typically peaks 24-72 hours post-transfection and may decline afterward, depending on cell viability and mRNA stability.
View the frequently asked questions answered by Creative Biolabs Support.
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Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
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| CAT | Product Name | Application | Type |
|---|---|---|---|
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| PABL-193 | Recombinant Human Anti-HIV-1 gp41-M-MAT Antibody | Neut, FuncS | IgG |
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| PNBL-020 | Recombinant Anti-HIV ENV VHH Single Domain Antibody (PNBL-020) | ELISA, SPR, Neut, FuncS | Llama VHH |
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| PFBZ-205 | Recombinant Human Anti-HIV-1 gp120 Antibody Fab Fragment (PGT121) | Neut, ELISA | Fab |
| PSBL-435 | Recombinant Human Anti-DENV Env Antibody scFv Fragment (EDE1 A11) | Neut | scFv |
| PSBL-436 | Human Anti-Env Recombinant Antibody; scFv Fragment (PSBL-436) | Neut | Human scFv |
| PSBL-437 | Human Anti-Env Recombinant Antibody; scFv Fragment (PSBL-437) | Neut | Human scFv |
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| PFBL-435 | Recombinant Human Anti-DENV Env Antibody Fab Fragment (EDE1 A11) | Neut | Fab |
| PFBL-436 | Human Anti-Env Recombinant Antibody; Fab Fragment (PFBL-436) | Neut | Human Fab |
| PFBL-437 | Human Anti-Env Recombinant Antibody; Fab Fragment (PFBL-437) | Neut | Human Fab |
| PFBL-438 | Human Anti-Env Recombinant Antibody; Fab Fragment (PFBL-438) | Neut | Human Fab |
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| CAT | Product Name | Application | Type |
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| MHC-CN0617 | PE-H-2Dd/HIV Env (IPGRAFYA) MHC Tetramer | FCM, IHC | |
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| MHC-CN0619 | FITC-H-2Dd/HIV Env (IPGRAFYA) MHC Tetramer | FCM, IHC | |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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