Recombinant Human Anti-F11R Antibody (Hz6F4-2) (CAT#: HPAB-0137-FY)

Recombinant monoclonal antibody to F11R. This product is a recombinant humanized antibody that recognizes human F11R.


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ELISA

Figure 1 Illustrates the antibody binding to JAM-A ECD by ELISA.

Figure 1 Illustrates the antibody binding to JAM-A ECD by ELISA.

Binding activity of chimeric and humanized antibodies (A: heavy chain; B: light chain) to the JAM-A extracellular domain (ECD) was measured by ELISA where an anti-human Ckappa conjugate was used to detect the purified antibodies. Dose-dependent binding activities onto plastic-coated JAM-A ECD were measured at 450 nm

ELISA

Figure 2 Illustrates the competition binding of biotinylated murine 6F4 to JAM-A ECD by ELISA.

Figure 2 Illustrates the competition binding of biotinylated murine 6F4 to JAM-A ECD by ELISA.

Competition binding of biotinylated murine 6F4 Mab to the JAM-A extracellular domain (ECD) by chimeric and humanized (A: heavy chain; B: light chain) antibodies was measured by ELISA. Dose-dependent displacement of biotinylated 6F4 was monitored onto plastic-coated JAM-A ECD.

IF

Figure 3 Illustrate the Down regulation of JAM-A by the Mab Hz6F4-2 using immunofluorescence staining.

Figure 3 Illustrate the Down regulation of JAM-A by the Mab Hz6F4-2 using immunofluorescence staining.

WB

Figure 4 Illustrate the Down regulation of JAM-A by the Mab Hz6F4-2 using A: western-blot, B: densitometry analysis.

Figure 4 Illustrate the Down regulation of JAM-A by the Mab Hz6F4-2 using A: western-blot, B: densitometry analysis.

WB

Figure 5 Illustrates the effect of the Mab Hz6F4-2 on adhesion molecule expression by western blot.

Figure 5 Illustrates the effect of the Mab Hz6F4-2 on adhesion molecule expression by western blot.


Specifications

  • Host Species
  • Human
  • Derivation
  • Humanized
  • Type
  • Human IgG4, κ
  • Specificity
  • Human F11R
  • Species Reactivity
  • Human
  • Clone
  • Hz6F4-2
  • Applications
  • In vivo activity, ELISA, IF, WB
  • Related Disease
  • Cancer

Product Property

  • Purity
  • >95% as determined by analysis by SDS-PAGE
  • Storage
  • Store at -20°C for long-term storage. Avoid freeze/thaw cycles.

Applications

  • Application Notes
  • The F11R antibody has been reported in applications of In vivo activity, ELISA, IF, WB.

Target

  • Alternative Names
  • JAM; KAT; JAM1; JAMA; JCAM; CD321; PAM-1

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "Clone Hz6F4-2"

See other products for "F11R"

Single-domain Antibody

CAT Product Name Application Type
NAB-914-VHH Recombinant Anti-Human F11R VHH Single Domain Antibody ICC, FC, WB, FUNC Llama VHH

Rabbit Monoclonal Antibody

CAT Product Name Application Type
MOR-1223 Hi-Affi™ Rabbit Anti-F11R Recombinant Antibody (clone DS1223AB) WB, IHC-P Rabbit IgG

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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