Mouse Anti-FCGR3A Recombinant Antibody (VS-1225-XY79)
CAT#: VS-1225-XY79
This engineered immunoglobulin targets FCGR3A, with a specific Fab and stable Fc. It has tailored affinity for research, applicable in ELISA, WB, and IHC for FCGR3A detection in biological samples.
Specifications
- Host Animal
- Mouse
- Applications
- WB, FC, IP
- Specificity
- FCGR3A
- Target
- FCGR3A
- Species Reactivity
- Human
- Type
- Mouse IgG1
- Purity
- >95%, determined by SDS-PAGE
- Purification
- Protein A purified
- Format
- Liquid
- Buffer
- PBS, pH 7.4
- Preservative
- No preservative
- Storage
- Store at 4°C within one or two weeks. Store at -20°C for long term. Avoid repeated freeze/thaw cycles. Refer to the COA file for specifics.
Target
- Introduction
- This gene encodes a receptor for the Fc portion of immunoglobulin G, and it is involved in the removal of antigen-antibody complexes from the circulation, as well as other responses, including antibody dependent cellular mediated cytotoxicity and antibody dependent enhancement of virus infections. This gene (FCGR3A) is highly similar to another nearby gene (FCGR3B) located on chromosome 1. The receptor encoded by this gene is expressed on natural killer (NK) cells as an integral membrane glycoprotein anchored through a transmembrane peptide, whereas FCGR3B is expressed on polymorphonuclear neutrophils (PMN) where the receptor is anchored through a phosphatidylinositol (PI) linkage. Mutations in this gene are associated with immunodeficiency 20, and have been linked to susceptibility to recurrent viral infections, susceptibility to systemic lupus erythematosus, and alloimmune neonatal neutropenia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
- Alternative Names
- CD16, FCG3, CD16A, FCGR3, IGFR3, IMD20, FCR-10, FCRIII, CD16-II, FCGRIII, FCRIIIA, FcGRIIIA
- Gene ID
- 2214
- UniProt ID
- P08637
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Downloadable Resources
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Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Recommended Dilution Buffer
- CAT
- Product Name
Secondary Antibody
- CAT
- Product Name
Isotype Control
- CAT
- Product Name
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| CAT | Product Name | Application | Type |
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| CAT | Product Name | Application | Type |
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| CAT | Product Name | Application | Type |
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| CAT | Product Name | Application | Type |
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| CAT | Product Name | Application | Type |
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| CAT | Product Name | Application | Type |
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| CAT | Product Name | Application | Type |
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| HPAB-0787-FY-F(E) | Human Anti-FCGR3A Recombinant Antibody (clone A2); scFv Fragment | Cyt | Human scFv |
| CAT | Product Name | Application | Type |
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| CAT | Product Name | Application | Type |
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