Mouse Anti-FCGR3A Recombinant Antibody (clone 3G8); Fab Fragment
CAT#: DrMAB-979
Recombinant Mouse Antibody binds selectively to Mouse FCGR3A.
Published Data
Gene Expression
ELISA
Figure 2 Shows results from an ELISA for binding of sCD16A by CD16A binding proteins.
FC
Figure 3 Shows results of a cell based competition assay.
The aglycosylated humanized antibodies shown compete with aglycosylated chimeric antibody for binding to CHO-K1 cells expressing the extracellular domain of CD16A.
Inhib
Figure 4 Shows inhibition of binding of sCD16A to immune complexes.
Hu3G8-1.1 is an antibody with the heavy chain Hu3G8VH-1, and the light chain Hu3G8VL-1.
Inhib
Figure 5 Shows ITP protection in mice injected i.v. with mAb 3G8 (0.5 μg/g) or human IVIG (1 mg/g) one hour before ch6A6 i.p. injection.
ADCC
Figure 6 Shows inhibition of ch4D5 mediated antibody-dependent cell-mediated cytotoxicity (ADCC) by humanized 3G8 antibodies.
ADCC
Figure 7 Show inhibition of ch4-4-20 mediated ADCC by humanized 3G8 antibodies.
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Normal Tissue
Figure 1 Cerebral cortex
Neuropil
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/32435/70986_B_7_5.jpg
Normal Tissue
Figure 2 Lung
Macrophages
Staining: High
Intensity: Strong
Quantity:>75%
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/32435/70986_A_1_4.jpg
Normal Tissue
Figure 3 Lymph node
Non-germinal center cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/32435/70986_A_9_8.jpg
RNA Expression
Figure 4 RNA cell line category: Not detected
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000203747-FCGR3A
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Specifications
- Immunogen
- Human polymorphonuclear leukocytes
- Host Species
- Mouse
- Type
- Mouse Fab
- Specificity
- Human FCGR3A
- Species Reactivity
- Human, Monkey
- Clone
- 3G8
- Applications
- FC, ELISA, Inhib, ADCC
Product Property
- Purification
- Purified with Protein A affinity chromatography
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- 1 mg/mL (lot specific)
- Buffer
- 50 mM Sodium Phosphate, 100 mM Potassium Chloride, 150mM NaCl, pH 7.5
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- The FCGR3A antibody has been reported in applications of Flow Cytometry, Enzyme-linked Immunosorbent Assay, Inhibition, Antibody-dependent Cell-mediated Cytotoxicity.
Target
- Alternative Names
- FCGR3A; Fc fragment of IgG, low affinity IIIa, receptor (CD16a); Fc fragment of IgG, low affinity IIIa, receptor for (CD16), FCG3, FCGR3; low affinity immunoglobulin gamma Fc region receptor III-A; CD16; CD16a; FcgammaRIIIA; CD16a antigen; fc-gamma RIII;
- Gene ID
- 2214
- UniProt ID
- M9MML0
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "Clone 3G8"
- CAT
- Product Name
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Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| DrMAB-978 | Recombinant Mouse Anti-Human FCGR3A Antibody F(ab')2 Fragment, clone 3G8 | FC | F(ab')2 |
| HPAB-M0271-YC-F(E) | Human Anti-FCGR3A Recombinant Antibody (clone M/YC-27); Fab Fragment | ELISA | Human Fab |
| HPAB-N0090-YC-F(E) | Human Anti-FCGR3A Recombinant Antibody; Fab Fragment (HPAB-N0090-YC-F(E)) | FuncS | Human Fab |
| HPAB-0787-FY-S(P) | Human Anti-FCGR3A Recombinant Antibody (clone A2); Fab Fragment | Cyt | Human Fab |
| HPAB-0788-FY-S(P) | Human Anti-FCGR3A Recombinant Antibody (clone B2); Fab Fragment | Cyt | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NABG-063 | Recombinant Anti-Human FCGR3A VHH Single Domain Antibody | WB, ELISA, IHC, FuncS | Llama VHH |
| HPAB-1025WJ | Recombinant Camelid Anti-FCGR3A Single Domain Antibody | ELISA | Camelid VHH |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-040WM | Anti-Human FCGR3A Recombinant Antibody (hu3G8) | ELISA | Humanized Antibody |
| TAB-040WM-S(P) | Anti-Human FCGR3A Recombinant Antibody scFv Fragment (hu3G8) | ELISA | Humanized Antibody |
| TAB-040WM-F(E) | Anti-Human FCGR3A Recombinant Antibody Fab Fragment (hu3G8) | ELISA | Humanized Antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-041WM | Anti-Human FCGR3A Recombinant Antibody (ch3G8) | ELISA | Chimeric Antibody (human/mouse) |
| TAB-041WM-S(P) | Anti-Human FCGR3A Recombinant Antibody scFv Fragment (ch3G8) | ELISA | Chimeric Antibody (human/mouse) |
| TAB-041WM-F(E) | Anti-Human FCGR3A Recombinant Antibody Fab Fragment (ch3G8) | ELISA | Chimeric Antibody (human/mouse) |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-0275MC | Recombinant Mouse Anti-Human FCGR3A Antibody. | FC, IP, IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-0384CT | Recombinant Mouse anti-Human FCGR3A Monoclonal antibody (NFN-265) | FC, IP, WB | |
| HPAB-M0271-YC | Human Anti-FCGR3A Recombinant Antibody (clone M/YC-27) | ELISA | Human IgG1 |
| HPAB-N0090-YC | Human Anti-FCGR3A Recombinant Antibody (HPAB-N0090-YC) | FuncS | Human IgG |
| HPAB-0787-FY | Human Anti-FCGR3A Recombinant Antibody (clone A2) | Cyt | Human IgG1 |
| VS-0723-WK206 | Human Anti-FCGR3A Recombinant Antibody (VS-0723-WK206) | ELISA, FC | Chimeric (rabbit/human) IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-797CQ | Mouse Anti-FCGR3A Recombinant Antibody (clone 3G8) | FC, IHC-Fr, ICC, IP, Stim, Costim, Block | Mouse IgG1, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-798CQ | Mouse Anti-FCGR3A Recombinant Antibody (clone B73.1) | FC, FuncS, Neut | Mouse IgG1, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1275 | Hi-Affi™ Rabbit Anti-FCGR3A Recombinant Antibody (clone DS1275AB) | WB, ICC | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-M0271-YC-S(P) | Human Anti-FCGR3A Recombinant Antibody (clone M/YC-27); scFv Fragment | ELISA | Human scFv |
| HPAB-N0090-YC-S(P) | Human Anti-FCGR3A Recombinant Antibody; scFv Fragment (HPAB-N0090-YC-S(P)) | FuncS | Human scFv |
| HPAB-0787-FY-F(E) | Human Anti-FCGR3A Recombinant Antibody (clone A2); scFv Fragment | Cyt | Human scFv |
| HPAB-0788-FY-F(E) | Human Anti-FCGR3A Recombinant Antibody (clone B2); scFv Fragment | Cyt | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0724-YC1558 | AbPlus™ Anti-Fcgr3a Magnetic Beads (VS-0724-YC1558) | IP, Protein Purification |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-1024-XY80 | Mouse Anti-NHP FCGR3A Recombinant Antibody (clone 3G8) | FC | Mouse IgG1, kappa |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-FY213 | Human Anti-FCGR3A (clone hu3G8) scFv-Fc Chimera | ELISA | Human IgG1, scFv-Fc |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS13-YC388 | CytoStream™ Rabbit Anti-FCGR3A Polyclonal Antibody (VS13-YC388) | WB, ELISA, IHC-P, IHC-Fr, FC, IF | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC21 | Recombinant Anti-FCGR3A Vesicular Antibody, EV Displayed (VS-0425-YC21) | ELISA, FC, Cell-uptake |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY2483 | Anti-Mouse FCGR3A Immunohistochemistry Kit | IHC | |
| VS-0525-XY2485 | Anti-Rat FCGR3A Immunohistochemistry Kit | IHC |
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