Mouse Anti-FCGR3A Recombinant Antibody (clone 3G8); Fab Fragment (CAT#: DrMAB-979)
Recombinant Mouse Antibody binds selectively to Mouse FCGR3A.
Specific Inquiry
ELISA
Figure 2 Shows results from an ELISA for binding of sCD16A by CD16A binding proteins.
FC
Figure 3 Shows results of a cell based competition assay.
The aglycosylated humanized antibodies shown compete with aglycosylated chimeric antibody for binding to CHO-K1 cells expressing the extracellular domain of CD16A.
Inhib
Figure 4 Shows inhibition of binding of sCD16A to immune complexes.
Hu3G8-1.1 is an antibody with the heavy chain Hu3G8VH-1, and the light chain Hu3G8VL-1.
Inhib
Figure 5 Shows ITP protection in mice injected i.v. with mAb 3G8 (0.5 μg/g) or human IVIG (1 mg/g) one hour before ch6A6 i.p. injection.
ADCC
Figure 6 Shows inhibition of ch4D5 mediated antibody-dependent cell-mediated cytotoxicity (ADCC) by humanized 3G8 antibodies.
ADCC
Figure 7 Show inhibition of ch4-4-20 mediated ADCC by humanized 3G8 antibodies.
Specifications
- Immunogen
- Human polymorphonuclear leukocytes
- Host Species
- Mouse
- Type
- Mouse Fab
- Specificity
- Human FCGR3A
- Species Reactivity
- Human, Monkey
- Clone
- 3G8
- Applications
- FC, ELISA, Inhib, ADCC
Product Property
- Purification
- Purified with Protein A affinity chromatography
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- 1 mg/mL (lot specific)
- Buffer
- 50 mM Sodium Phosphate, 100 mM Potassium Chloride, 150mM NaCl, pH 7.5
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- The FCGR3A antibody has been reported in applications of Flow Cytometry, Enzyme-linked Immunosorbent Assay, Inhibition, Antibody-dependent Cell-mediated Cytotoxicity.
Target
- Alternative Names
- FCGR3A; Fc fragment of IgG, low affinity IIIa, receptor (CD16a); Fc fragment of IgG, low affinity IIIa, receptor for (CD16), FCG3, FCGR3; low affinity immunoglobulin gamma Fc region receptor III-A; CD16; CD16a; FcgammaRIIIA; CD16a antigen; fc-gamma RIII;
- Gene ID
- 2214
- UniProt ID
- M9MML0
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "Clone 3G8"
See other products for "FCGR3A"
Select a product category from the dropdown menu below to view related products.
Please select product type
Fab Antibody Products
Single Domain Antibody Products
Humanized Antibody Products
Chimeric Antibody Products
Mouse Antibody Products
Blocking Antibody Products
Neutralizing Antibody Products
Rabbit Monoclonal Antibody Products
IgG Antibody Products
ScFv Antibody Products
Antibody Magnetic Beads
Non-Human Primate (NHP) Antibody Products
ScFv-Fc Chimera Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| DrMAB-978 | Recombinant Mouse Anti-Human FCGR3A Antibody F(ab')2 Fragment, clone 3G8 | FC | F(ab')2 |
| HPAB-M0271-YC-F(E) | Human Anti-FCGR3A Recombinant Antibody (clone M/YC-27); Fab Fragment | ELISA | Human Fab |
| HPAB-N0090-YC-F(E) | Human Anti-FCGR3A Recombinant Antibody; Fab Fragment (HPAB-N0090-YC-F(E)) | FuncS | Human Fab |
| HPAB-0787-FY-S(P) | Human Anti-FCGR3A Recombinant Antibody (clone A2); Fab Fragment | Cyt | Human Fab |
| HPAB-0788-FY-S(P) | Human Anti-FCGR3A Recombinant Antibody (clone B2); Fab Fragment | Cyt | Human Fab |
Customer Reviews and Q&As
There are currently no Customer reviews or questions for DrMAB-979. Click the button above to contact us or submit your feedback about this product.
Popular products with customers
Application: IF, IP, Neut, FuncS, ELISA, FC, ICC
Application: WB, ELISA, IP, FC, FuncS, Neut, IF
Application: WB, Neut, ELISA, IF, IP, FuncS, FC
Application: Neut, ELISA, FuncS
Application: WB, Neut, FuncS
-1.png)
Application: WB, ELISA
Application: WB, IHC, ELISA, FC
Application: WB, ELISA, IF, FuncS, Apop, BA
Application: Neut, FC, IHC-Fr, IP, BA
For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
