Recombinant Human Anti-fHbp Antibody (chJAR 1) (CAT#: FAMAB-0136CQ)
Recombinant Human Antibody clone chJAR 1, which is specific to N. meningitidis fHbp. JAR 1 inhibited binding of fH to fHbp and had human complement-mediated bactericidal activity. It inhibited fH binding, had human complement-mediated bactericidal activity.
Specific Inquiry
ELISA
Figure 1 Inhibition of binding of a fixed concentration (1 µg/ml) of anti-fHbp mAbs to recombinant fHbp as measured by ELISA.
Red triangles: inhibition of binding of mAb502 (IgG2a) by JAR 1 (IgG3). Green circles: Inhibition of binding of JAR 1 by mAb502. Error bars represent ranges in independent assays.
FC
Figure 2 Binding of JAR 1 to yeast clones displaying randomly mutated fHbp on their surface.
A representative clone is positive for binding to JAR 1 (red solid line) and a control anti-fHbp mAb, JAR 5 (blue dashed line).
Specifications
- Host Species
- Human
- Derivation
- Chimeric (mouse/human)
- Type
- Chimeric (mouse/human) IgG1
- Specificity
- N. meningitidis fHbp
- Species Reactivity
- N. meningitidis
- Clone
- chJAR 1
- Applications
- Used for immunoassay techniques such as: Enzyme-Linked Immunosorbent Assay; Flow Cytometry; Inhib
- Related Disease
- Meningococcal disease
Product Property
- Purity
- >95% as determined by analysis by SDS-PAGE
- Storage
- Store at -20°C for long-term storage. Avoid freeze/thaw cycles.
Target
- Alternative Names
- fhbP; Factor H-binding protein
- UniProt ID
- C6KHT4
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Mouse Antibody Products
Blocking Antibody Products
IgG Antibody Products
Fab Antibody Products
ScFv Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-070WM | Anti-N. meningitidis fHbp Recombinant Antibody (502) | ELISA, FC, Inhib | |
| TAB-070WM-S(P) | Anti-N. meningitidis fHbp Recombinant Antibody scFv Fragment (502) | WB, FC | |
| TAB-070WM-F(E) | Anti-N. meningitidis fHbp Recombinant Antibody Fab Fragment (502) | WB, FC |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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