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Rabbit Anti-FMR1 Recombinant Antibody (clone JM91-41) (CAT#: MRO-0596-CN)

This antibody is a rabbit monoclonal antibody that is capable of binding to FMR1.


See more Engineered Antibody products for FMR1
Specific Inquiry
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  • Purity:
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  • Gene Expression
  • Datasheet
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  • COA
Subcellular Location and Protein Expression
Figure 1 IF staining of human cell line U-251 MG
Figure 1 IF staining of human cell line U-251 MG
(Immunofluorescent staining of human cell line U-251 MG shows localization to cytosol.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/50118/if_selected.jpg
Figure 2 IF staining of human cell line A-431
Figure 2 IF staining of human cell line A-431
(Immunofluorescent staining of human cell line A-431 shows localization to cytosol.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/12444/if_selected.jpg
Figure 3 IHC staining of human testis
Figure 3 IHC staining of human testis
(Immunohistochemical staining of human testis shows strong cytoplasmic and nuclear positivity in cells in seminiferous ducts.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/56084/135535_A_6_6_selected.jpg
Normal Tissue
Figure 4 Cerebral cortex
Figure 4 Cerebral cortex
(Glial cells
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
Neuronal cells
Staining:High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/50118/135515_B_8_5.jpg
Figure 5 Thyroid gland
Figure 5 Thyroid gland
(Glandular cells
Staining:High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/50118/135515_B_1_5.jpg
Figure 6 Colon
Figure 6 Colon
(Endothelial cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Glandular cells
Staining:High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
Peripheral nerve/ganglion
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/50118/135515_A_9_3.jpg
Figure 7 Kidney
Figure 7 Kidney
(Cells in glomeruli
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
Cells in tubules
Staining:High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/50118/135515_A_8_5.jpg
Figure 8 Testis
Figure 8 Testis
(Cells in seminiferous ducts
Staining:Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous
Leydig cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/50118/135515_A_6_6.jpg
RNA Expression
Figure 9 RNA cell line category: Low cell line specificity
Figure 9 RNA cell line category: Low cell line specificity
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000102081-FMR1

Specifications

  • Immunogen
  • Human FMRP aa 1-100
  • Host Species
  • Rabbit
  • Type
  • Rabbit IgG
  • Specificity
  • Human FMR1
  • Species Reactivity
  • Human, Mouse, Rat
  • Clone
  • JM91-41
  • Applications
  • WB, IF, IHC
  • Conjugate
  • Unconjugated

Product Property

  • Purification
  • Purified with Protein A affinity chromatography
  • Purity
  • >95% as determined by SDS-PAGE
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Buffer
  • TBS, pH 7.4, 1% BSA, 40% Glycerol
  • Preservative
  • 0.05% Sodium azide
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

  • Alternative Names
  • Fragile X Mental Retardation 1; Fragile X Mental Retardation Protein 1; FMRP; Synaptic Functional Regulator FMR1; Premature Ovarian Failure 1; Protein FMR-1; FRAXA; POF1; POF;

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "FMR1"

Recombinant Antibody

CAT Product Name Application Type
MOB-2078MZ Recombinant Mouse Anti-Fruit fly Drosophila melanogaster FMR1 Antibody (clone 7B26) ELISA, ICC/IF, IP, WB Mouse antibody
ZG-0354J Mouse Anti-FMR1 Recombinant Antibody (ZG-0354J) WB, IHC, IF, ELISA Mouse IgG
VS3-XY716 Mouse Anti-FMR1 Recombinant Antibody (clone 4G9) ELISA, WB, IHC, ICC Mouse IgG1

Chicken IgY Antibody

CAT Product Name Application Type
BRD-0676MZ Chicken Anti-FMRP Polyclonal IgY WB Chicken antibody

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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