Human Anti-GDF15 Recombinant Antibody (clone Ponsegromab) (CAT#: VS-0723-WK30)
This product is a humanized IgG1 antibody that recognizes human GDF15, which is expressed in a broad range of cell types, acts as a pleiotropic cytokine and is involved in the stress response program of cells after cellular injury. Ponsegromab is recommended for flow cytometry at a dilution of 1:100.
Specific Inquiry
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line U-251 MG
(Immunofluorescent staining of human cell line Hep G2 shows localization to the Golgi apparatus.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/11191/1404_F3_1_selected.jpg
(Immunofluorescent staining of human cell line Hep G2 shows localization to the Golgi apparatus.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/11191/1404_F3_1_selected.jpg
Figure 2 Placenta
(Cytotrophoblasts
Staining: Medium
Intensity: Moderate
Quantity:>75%
Syncytiotrophoblasts - cell body
Staining: High
Intensity: Strong
Quantity:>75%
Syncytiotrophoblasts - microvilli
Staining: High
Intensity: Strong)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/11191/27866_A_1_7.jpg
(Cytotrophoblasts
Staining: Medium
Intensity: Moderate
Quantity:>75%
Syncytiotrophoblasts - cell body
Staining: High
Intensity: Strong
Quantity:>75%
Syncytiotrophoblasts - microvilli
Staining: High
Intensity: Strong)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/11191/27866_A_1_7.jpg
Figure 3 RNA cell line category: Cell line enhanced (BEWO, Hep G2, HHSteC, TIME)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000130513-GDF15
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000130513-GDF15
Specifications
- Immunogen
- Recombinant human GDF15 protein
- Host Species
- Human
- Derivation
- Humanized
- Type
- Human IgG1
- Specificity
- Human GDF15
- Species Reactivity
- Human
- Clone
- Ponsegromab
- Applications
- FC
- Conjugate
- Unconjugated
Product Property
- Clonality
- Monoclonal
- Purification
- Protein A purified
- Purity
- >95%
- Format
- Lyophilized
- Buffer
- Lyophilized from sterile PBS (pH 7.4) with 5%-8% trehalose.
- Preservative
- No Preservative
- Storage
- Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
- Shipping
- Ice packs
Applications
- Application Notes
- Flow Cytometry: 1/100
Target
- Alternative Names
- GDF-15; MIC-1; MIC1; NAG-1; PDF; PLAB; PTGFB
- Gene ID
- 9518
- UniProt ID
- Q99988
- Long Name
- Growth Differentiation Factor 15
Recommended Products
Isotype Control
Secondary Antibody
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "GDF15"
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-391 | Recombinant Anti-human GDF15 Antibody | ELISA, WB, IF, FuncS | IgG |
| HPAB-M0527-YC | Human Anti-GDF15 Recombinant Antibody (HPAB-M0527-YC) | ELISA, Block | Human IgG |
| HPAB-M0528-YC | Human Anti-GDF15 Recombinant Antibody (HPAB-M0528-YC) | ELISA, Block | Human IgG |
| ZG-0684J | Rabbit Anti-GDF15 Recombinant Antibody (clone 8E5) | ELISA, IHC | Rabbit IgG |
| VS-0723-WK97 | Human Anti-GDF15 Recombinant Antibody (VS-0723-WK97) | FC | Chimeric (rabbit/human) IgG1 |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHH-391-S(P) | Recombinant Human Anti-human GDF15 Antibody scFv Fragment | ELISA, IP, FuncS | scFv |
| HPAB-M0522-YC-S(P) | Human Anti-GDF15 Recombinant Antibody; scFv Fragment (HPAB-M0522-YC-S(P)) | ELISA, Block | Human scFv |
| HPAB-M0523-YC-S(P) | Human Anti-GDF15 Recombinant Antibody; scFv Fragment (HPAB-M0523-YC-S(P)) | ELISA, Block | Human scFv |
| HPAB-M0524-YC-S(P) | Human Anti-GDF15 Recombinant Antibody; scFv Fragment (HPAB-M0524-YC-S(P)) | ELISA, Block | Human scFv |
| HPAB-M0525-YC-S(P) | Human Anti-GDF15 Recombinant Antibody; scFv Fragment (HPAB-M0525-YC-S(P)) | ELISA, Block | Human scFv |
Humanized Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0781CL | Anti-Human GDF15 Recombinant Antibody | ELISA, WB | Humanized antibody |
| TAB-0781CL-S(P) | Anti-Human GDF15 Recombinant Antibody scFv Fragment | ELISA, WB | Humanized antibody |
| TAB-0781CL-F(E) | Anti-Human GDF15 Recombinant Antibody Fab Fragment | ELISA, WB | Humanized antibody |
Mouse Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0782CL | Anti-Human GDF15 Recombinant Antibody (A10.3) | ELISA, IHC, WB | |
| TAB-0783CL | Anti-Human GDF15 Recombinant Antibody (B2.2) | ELISA, FC | |
| TAB-0785CL | Mouse Anti-GDF15 Recombinant Antibody (TAB-0785CL) | ELISA, FC, WB | Mouse IgG |
| TAB-0786CL | Mouse Anti-GDF15 Recombinant Antibody (TAB-0786CL) | ELISA, FC, WB | Mouse IgG |
| TAB-0787CL | Mouse Anti-GDF15 Recombinant Antibody (TAB-0787CL) | ELISA, FC, WB | Mouse IgG |
Human Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0784CL | Human Anti-GDF15 Recombinant Antibody (TAB-0784CL) | ELISA, FC | Human IgG |
| TAB-0784CL-S(P) | Human Anti-GDF15 Recombinant Antibody; scFv Fragment (TAB-0784CL-S(P)) | ELISA, FC | Human scFv |
| TAB-0784CL-F(E) | Human Anti-GDF15 Recombinant Antibody; Fab Fragment (TAB-0784CL-F(E)) | ELISA, FC | Human Fab |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1421 | Hi-Affi™ Rabbit Anti-GDF15 Recombinant Antibody (clone DS1421AB) | WB | Rabbit IgG |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0334-CN-F(E) | Mouse Anti-GDF15 Recombinant Antibody; Fab Fragment (HPAB-0334-CN-F(E)) | ELISA, WB | Mouse Fab |
| HPAB-0335-CN-F(E) | Mouse Anti-GDF15 Recombinant Antibody; Fab Fragment (HPAB-0335-CN-F(E)) | ELISA, WB | Mouse Fab |
| HPAB-0336-CN-F(E) | Mouse Anti-GDF15 Recombinant Antibody; Fab Fragment (HPAB-0336-CN-F(E)) | ELISA, WB | Mouse Fab |
| HPAB-0337-CN-F(E) | Human Anti-GDF15 Recombinant Antibody; Fab Fragment (HPAB-0337-CN-F(E)) | ELISA, WB | Human Fab |
| HPAB-0142-YJ-F(E) | Human Anti-GDF15 Recombinant Antibody; Fab Fragment (HPAB-0142-YJ-F(E)) | Inhib, FuncS | Human Fab |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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