Human Anti-GPA33 Recombinant Antibody (clone huA33) (CAT#: FAMAB-1151CQ)
This product is a recombinant human antibody that recognizes GPA33. The antibody was purified by affinity chromatography. It can be used in Depletion, ELISA, IF, IHC.
Specific Inquiry
FC
Figure 1 In vitro activation of human PBMCs by huA33-BsAb.
Quantification of dividing cells based on CFSE dye dilution 96 hours after incubation with Colo205 cells and huA33 antibodies.
Wu, Z., Guo, H. F., Xu, H., & Cheung, N. K. V. (2018). Development of a tetravalent anti-GPA33/anti-CD3 bispecific antibody for colorectal cancers. Molecular cancer therapeutics, 17(10), 2164-2175.
Cyt
Figure 2 In vitro cytotoxicity induced by huA33-BsAb.
Cytotoxicity elicited by huA33-BsAb against different target tumor cell lines and control cells. ATCs were used as effector cells at an E:T of 10:1. Cells were incubated for 16 hours before reading.
Wu, Z., Guo, H. F., Xu, H., & Cheung, N. K. V. (2018). Development of a tetravalent anti-GPA33/anti-CD3 bispecific antibody for colorectal cancers. Molecular cancer therapeutics, 17(10), 2164-2175.
IHC
Figure 3 IHC images of CD3 staining.
Representative images (200× magnifications) of IHC staining of abdominal LS174T tumor sections collected 5 days after i.v. ATC were shown.
Wu, Z., Guo, H. F., Xu, H., & Cheung, N. K. V. (2018). Development of a tetravalent anti-GPA33/anti-CD3 bispecific antibody for colorectal cancers. Molecular cancer therapeutics, 17(10), 2164-2175.
Specifications
- Host Species
- Human
- Type
- Human IgG1
- Species Reactivity
- Human
- Clone
- huA33
- Applications
- FC, Cyt, IHC
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- This antibody has been reported for use in Cytotoxicity, Immunohistochemistry and Flow Cytometry.
Target
- Alternative Names
- Glycoprotein A33; Glycoprotein A33 (Transmembrane); Transmembrane Glycoprotein A33; Cell Surface A33 Antigen; A33
- Gene ID
- 10223
- UniProt ID
- Q99795
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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See other products for "Clone huA33"
See other products for "GPA33"
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2119z | Mouse Anti-GPA33 Recombinant Antibody (MOB-2119z) | IHC, WB | Mouse IgG1 |
| MOB-069LC | Rat Anti-GPA33 Recombinant Antibody (clone YC069) | ELISA, FC, WB | Rat IgG |
| HPAB-1717-FY | Human Anti-GPA33 Recombinant Antibody (clone 263A17) | ELISA | Human IgG |
| HPAB-1718-FY | Human Anti-GPA33 Recombinant Antibody (clone 125M10AA) | ELISA | Human IgG |
| HPAB-1719-FY | Human Anti-GPA33 Recombinant Antibody (clone 125M165DAAA) | ELISA | Human IgG |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2119z-F(E) | Recombinant Anti-Human GPA33 Antibody Fab Fragment | FC, WB, FuncS | Fab |
| HPAB-1717-FY-S(P) | Human Anti-GPA33 Recombinant Antibody (clone 263A17); Fab Fragment | ELISA | Human Fab |
| HPAB-0521-YJ-F(E) | Human Anti-GPA33 Recombinant Antibody; Fab Fragment (HPAB-0521-YJ-F(E)) | WB, IP, FC, ELISA, FuncS | Chimeric (Mouse/Human) Fab |
| HPAB-0522-YJ-F(E) | Human Anti-GPA33 Recombinant Antibody; Fab Fragment (HPAB-0522-YJ-F(E)) | WB, IP, FC, ELISA, FuncS | Humanized Fab |
| FAMAB-0161WJ-F(E) | Human Anti-GPA33 Recombinant Antibody (clone A2); Fab Fragment | ELISA, WB, FC, IF | Human Fab |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2119z-S(P) | Recombinant Anti-Human GPA33 Antibody scFv Fragment | WB, FC, FuncS | scFv |
| HPAB-1717-FY-F(E) | Human Anti-GPA33 Recombinant Antibody (clone 263A17); scFv Fragment | ELISA | Human scFv |
| HPAB-0521-YJ-S(P) | Human Anti-GPA33 Recombinant Antibody; scFv Fragment (HPAB-0521-YJ-S(P)) | WB, IP, FC, ELISA, FuncS | Human scFv |
| HPAB-0522-YJ-S(P) | Human Anti-GPA33 Recombinant Antibody; scFv Fragment (HPAB-0522-YJ-S(P)) | WB, IP, FC, ELISA, FuncS | Human scFv |
| FAMAB-0161WJ-S(P) | Human Anti-GPA33 Recombinant Antibody (clone A2); scFv Fragment | ELISA, WB, FC, IF | Human scFv |
Immunotoxin
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AGTO-G034F | Anti-GPA33 immunotoxin (scFv)-α-sar | Cytotoxicity assay, Function study |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1485 | Hi-Affi™ Rabbit Anti-GPA33 Recombinant Antibody (clone DS1485AB) | IHC-P, IP, WB | Rabbit IgG |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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