CytoStream™ Rabbit Anti-GYS1 Recombinant Antibody (VS13-YC491) (CAT#: VS13-YC491)
The CytoStream™ Rabbit Anti-GYS1 Recombinant Antibody is specific for human and mouse GYS1. GYS1 encodes a glycogen synthase catalyzing glucose addition, associated with muscle storage disease through regulatory pathways affecting glycogen metabolism dynamics. The anti-GYS1 antibody was developed and selected by our CytoStream™ platform and the mAb is recommended for use in flow cytometry staining (1/50-1/100).
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Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
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Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line U-2 OS
(Immunofluorescent staining of human cell line U-2 OS shows localization to cytosol & microtubules.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/41598/if_selected.jpg
(Immunofluorescent staining of human cell line U-2 OS shows localization to cytosol & microtubules.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/41598/if_selected.jpg
Figure 2 IHC staining of human skeletal muscle
(Immunohistochemical staining of human skeletal muscle shows strong cytoplasmic positivity in myocytes.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/41598/91527_B_1_6_selected.jpg
(Immunohistochemical staining of human skeletal muscle shows strong cytoplasmic positivity in myocytes.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/41598/91527_B_1_6_selected.jpg
Figure 3 Skeletal muscle.
(High expression in skeletal muscle)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/7793/ihc_selected.jpg
(High expression in skeletal muscle)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/7793/ihc_selected.jpg
Figure 4 Heart muscle
(Cardiomyocytes Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/7793/18859_B_4_6.jpg
(Cardiomyocytes Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/7793/18859_B_4_6.jpg
Figure 5 Lymph node
(Germinal center cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/7793/18859_A_8_8.jpg
(Germinal center cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/7793/18859_A_8_8.jpg
Figure 6 Colon
(Endothelial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Glandular cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/7793/18859_A_7_3.jpg
(Endothelial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Glandular cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/7793/18859_A_7_3.jpg
Figure 7 Kidney
(Cells in glomeruli Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Cells in tubules Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/7793/18859_A_9_5.jpg
(Cells in glomeruli Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Cells in tubules Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/7793/18859_A_9_5.jpg
Figure 8 Testis
(Leydig cells Staining: High Intensity: Strong Quantity:>75% Sertoli cells Staining: Medium Intensity: Moderate Quantity: 75%-25%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/7793/18859_A_6_6.jpg
(Leydig cells Staining: High Intensity: Strong Quantity:>75% Sertoli cells Staining: Medium Intensity: Moderate Quantity: 75%-25%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/7793/18859_A_6_6.jpg
Figure 9 RNA cell line category: Low cell line specificity
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000104812-GYS1
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000104812-GYS1
Specifications
- Immunogen
- Recombinant human glycogen synthase, aa 638-737.
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human and Mouse GYS1
- Species Reactivity
- Human, Mouse
- Applications
- WB, ICC, IF, IHC-P, FC, IP
- Conjugate
- NONE
- Related Disease
- Muscle glycogen storage disease
Product Property
- Clonality
- Monoclonal
- Purification
- Protein A purified
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- TBS (pH 7.4) containing 40% Glycerol and 0.05% BSA.
- Preservative
- 0.05% Sodium azide
- Storage
- Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Shipping with ice pack.
Applications
- Application Notes
- Western blot (WB): 1/1000
Immunocytochemistry (ICC): 1/50-1/200
Immunofluorescence (IF): 1/50-1/200
Immunohistochemistry-paraffin (IHC-P): 1/50-1/200
Flow cytometry (FC): 1/50-1/100
Target
- Alternative Names
- Glycogen Synthase 1; Glycogen Synthase 1 (Muscle); EC 2.4.1.11; GYS; Glycogen [Starch] Synthase, Muscle; GSY;
- Gene ID
- 2997
- UniProt ID
- P13807
- Long Name
- Glycogen Synthase 1
- Sequence Similarities
- Belongs to the glycosyltransferase 3 family.
- Cellular Localization
- Cytosol; Inclusion body; Cell membrane
- Protein Refseq
- NP_001155059.1; NP_002094.2
- Function
- Transfers the glycosyl residue from UDP-Glc to the non-reducing end of alpha-1, 4-glucan.
Recommended Products
Secondary Antibody
Isotype Control
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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IHC Kit and Antibody Products: Precision Tools for Immunohistochemistry
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-0771MZ | Recombinant Mouse Anti-Human GYS1 Antibody (clone 4B8) | ELISA, ICC/IF, WB | Mouse antibody |
| MRO-0680-CN | Rabbit Anti-GYS1 Recombinant Antibody (clone CBACN-248) | WB, IF, IHC, IP, FC | Rabbit IgG |
| ZG-0700J | Rabbit Anti-GYS1 Recombinant Antibody (clone 1D1) | ELISA, WB, IF | Rabbit IgG |
| VS3-QX491 | Mouse Anti-GYS1 Recombinant Antibody (clone 2H1-C11-B9) | WB, IHC, ICC, FC, ELISA | Mouse IgG1 |
| VS3-CJ641 | Rabbit Anti-GYS1 (phospho S641) Recombinant Antibody (VS3-CJ641) | WB, ICC, IHC, IP | Rabbit IgG |
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