Rat Anti-Havcr1 Agonistic Antibody (VS-0724-XY29) (CAT#: VS-0724-XY29)
This product is a rat agonistic antibody binding to Havcr1 (Hepatitis A virus cellular receptor 1), which acts upstream of or within positive regulation of mast cell activation. This antibody was raised by immunising female Lewis strain rats subcutaneously with mouse TIM-1-Ig in complete Freund's adjuvant (CFA), followed by multiple 'boosting' with mouse TIM-1-Ig in PBS. This antibody specifically reacts with mouse Havcr1. It has been detected by Immunohistochemistry, Flow cytometry, Immunofluorescence and Agonistic assays.
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Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line A549
(Immunofluorescent staining of human cell line A549 shows localization to vesicles.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/7173/if_selected.jpg
(Immunofluorescent staining of human cell line A549 shows localization to vesicles.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/7173/if_selected.jpg
Figure 2 Colon
(Glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/75697/159393_A_7_3.jpg
(Glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/75697/159393_A_7_3.jpg
Figure 3 Rectum
(Glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/75697/159393_A_4_3.jpg
(Glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/75697/159393_A_4_3.jpg
Figure 4 Liver
(Cholangiocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/75697/159393_A_9_4.jpg
(Cholangiocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/75697/159393_A_9_4.jpg
Figure 5 Kidney
(Cells in tubules Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/75697/159393_A_7_5.jpg
(Cells in tubules Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/75697/159393_A_7_5.jpg
Figure 6 Testis
(Cells in seminiferous ducts Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Leydig cells Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/75697/159393_A_5_6.jpg
(Cells in seminiferous ducts Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Leydig cells Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/75697/159393_A_5_6.jpg
Figure 7 RNA cell line category: Group enriched (A549, CACO-2, RPTEC TERT1)
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000113249-HAVCR1
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000113249-HAVCR1
Specifications
- Immunogen
- This antibody was raised by immunising female Lewis strain rats (Harlan Sprague-Dawley) subcutaneously with mouse TIM-1-Ig in complete Freund's adjuvant (CFA), followed by multiple 'boosting' with mouse TIM-1-Ig in PBS.
- Host Species
- Rat
- Type
- Rat IgG2a, kappa
- Specificity
- Havcr1
- Species Reactivity
- Mouse
- Applications
- IHC, FC, IF, Agonistic assays
Product Property
- Purification
- Protein G purified
- Purity
- >95%, determined by SDS-PAGE
- Format
- Liquid
- Buffer
- PBS
- Preservative
- 0.02 % Proclin 300
- Storage
- Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
Target
Recommended Products
Isotype Control
Recommended Dilution Buffer
Secondary Antibody
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
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ScFv Antibody Products
Agonistic Antibody Products
Extracellular Vesicle (EV) Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0625CL-S(P) | Rat Anti-HAVCR1 Recombinant Antibody; scFv Fragment (TAB-0625CL-S(P)) | ELISA, WB, FC | Rat scFv |
| TAB-0626CL-S(P) | Rat Anti-HAVCR1 Recombinant Antibody; scFv Fragment (TAB-0626CL-S(P)) | ELISA, WB, FC | Rat scFv |
| TAB-0625CL-F(E) | Rat Anti-HAVCR1 Recombinant Antibody; Fab Fragment (TAB-0625CL-F(E)) | ELISA, WB, FC | Rat Fab |
| TAB-0626CL-F(E) | Rat Anti-HAVCR1 Recombinant Antibody; Fab Fragment (TAB-0626CL-F(E)) | ELISA, WB, FC | Rat Fab |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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